gene regulation and metabolism post-genomic computational approaches - julio collado-vides
gene regulation and metabolism post-genomic computational approaches - julio collado-vides
... questions of gene reg-
ulation and metabolism without explicit mention of the connection
between networks and the phenotype. One of the challenges, compu-
tationally, in understanding gene regulation ... transcriptome analyses combined with computational motif searches.
Chapter 5, by Julio Collado-Vides and colleagues, is devoted to com-
putational studies of gene regul...
gene regulation and metabolism
... questions of gene reg-
ulation and metabolism without explicit mention of the connection
between networks and the phenotype. One of the challenges, compu-
tationally, in understanding gene regulation ... transcriptome analyses combined with computational motif searches.
Chapter 5, by Julio Collado-Vides and colleagues, is devoted to com-
putational studies of gene regul...
The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... proliferation and metastasis (Hanahan and Weinberg
2000). Genes modified in cancer are classified as oncogenes and tumor sup-
pressor genes that have been activated by gain-of-function mutations and
inactivated ... than to pRb. C-terminal of
thepocketdomaininpRb,aregionknownastheC-domaincanbindthe
proto-oncogene products C-ABL and MDM2, thereby inhibiting C-ABL ty-
rosine kinase activ...
Tài liệu Báo cáo khoa học: Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics docx
... of RhoA, Cdc42 and Rac1, the most
A
B
CTGF
ToxB
- - - - + + + - - -
ToxB
- - - - + + + - - -
Y-27632
- - - - - - - + + +
Y-27632
- - - - - - + + +
GAPDH
CTGF mRNA Levels (%)
c s an ser s ... of
inhibitors.
A
Serum - + + +
S1P - + + +
GTP-RhoA
0 5 10 15 min
0 5 10 15 min
GTP-Cdc42
GTP-Cdc42
GTP...
Báo cáo khoa học: Improvement of a monopartite ecdysone receptor gene switch and demonstration of its utility in regulation of transgene expression in plants pdf
... of ligand for the activa-
tion of genes, and it does not support higher induc-
tion values as compared to the two-hybrid gene
switch [14]. All previous studies utilizing the mono-
partite gene ... USA)
combined with an on-column DNase digestion (RNase-Free
DNase set; Qiagen Inc.) to ensure DNA-free RNA prepara-
tions. First-strand cDNA was synthesized using the Strata-
Script First Stra...
Báo cáo khoa học: Characterization of the Drosophila Methoprene -tolerant gene product Juvenile hormone binding and ligand-dependent gene regulation potx
... FEBS
Characterization of the Drosophila Methoprene -tolerant
gene product
Juvenile hormone binding and ligand-dependent gene regulation
Ken Miura, Masahito Oda, Sumiko Makita and Yasuo Chinzei
Department of Medical ... S2 cells
the yeast GAL4-DNA binding domain fused to MET exerted JH- or JHA-
dependent activation of a reporter gene. Activation of the reporter gene
was highly JH-...
Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... tight and subtle
homeostatic control, involving gene- expression and metabolic
regulation of both topoisomerase I and DNA gyrase
Jacky L. Snoep
1,2
, Coen C. van der Weijden
1
, Heidi W. Andersen
2,3
, ... plasmid pHA2.
PHA5
The 1549-bp PCR f ragment described above w as digested
with EcoRV and SspI and a 572-bp fragment containing the
N-terminal part of the topA gene was isola...
Báo cáo khoa học: Functional interplay between viral and cellular SR proteins in control of post-transcriptional gene regulation pptx
... cycle, including positive-strand and
minus-strand DNA synthesis, pre-genomic RNA pack-
aging, and virion formation and release [17,18]. This
core protein is a phosphoprotein, and its function may
be ... [9].
Herpes simplex virus (HSV )-1 ICP27
The HSV-1 immediate-early protein ICP27 plays mul-
tiple roles in post-transcriptional regulation, and is
M C. Lai et al. Viral and cell...
Báo cáo khoa học: Gene regulation by tetracyclines Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes Christian Berens and Wolfgang Hillen pptx
... for the
4C- [120] and 6C-tet operators [114] have been constructed
with rtTA and also regulate tc-dependent expression units
efficiently. This now leaves us with different tTA- and rtTA-
operator ... K., Møller, A., Lund-
berg, C., Bjo
¨
rlund, A. & Johansen, T.E. (2002) Evaluation of
Tet-on system to avoid transgene down -regulation in ex vivo gene
transfer to the CNS. Gene The...
Báo cáo khoa học: Collective behavior in gene regulation: Metabolic clocks and cross-talking doc
... transcrip-
tion of target gene( s) and ⁄ or affects the functioning of
target cells and is fundamental for cellular cross-talk
and synchronization. Multicellular organisms are com-
posed of tissues and ... Lakin-Thomas PL (2000) Circadian rhythms: new func-
tions for old clock genes. Trends Genet 16, 135–142.
7 Schibler U & Naef F (2005) Cellular oscillators: rhyth-
mic gene ex...