Báo cáo khoa học: Organelle and translocatable forms of glyoxysomal malate dehydrogenase The effect of the N-terminal presequence pot

... through the organelle membrane [10–12]. If so, the relative stability of the two forms of the enzyme comes into question. Here the stability of the translocatable and the mature forms of the MDHs ... structure of the precursor and mature forms of the novel glyoxysomal MDH as well as the steady state parameters, the quaternary structure and...

Ngày tải lên: 30/03/2014, 15:20

... discourse. The difference in number of occurrences per I000 words between the Wizard -of- OZ con- dition and the Informal Spoken condition is much less than the same difference between the Wizard -of- OZ ... record of tAc li~ting of the names of the features). At least 50,C/o of the ,:set-adviser utterances had one or more prepositional phrases ks can be...

Ngày tải lên: 08/03/2014, 18:20

... isoforms can be found in seeds and leaves of the soapwort Saponaria of cinalis and some have been expressed in Escherichia coli and characterized biochemically [18,19]. The catalytic subunits of ... 4985 of intoxication. Neither the human leukemic cell line HSB-2 nor the Burkitt lymphoma Ramo cells showed any potentiation of cytotoxicity by addition of the KDEL sequ...

Ngày tải lên: 23/03/2014, 15:21

... approach, and there have been a number of clinical and experi- mental studies. The success of a gene therapy protocol depends on the selection of the candidate disease, tar- get cell, promoter region and ... instability and production of the target protein [43,44]. The results presented in this work agree with previous reports showing that the inclusion of a syn-...

Ngày tải lên: 29/03/2014, 21:20

... of the 3D structure of the receptor ECDs and for the characterization of the specificities of antibodies in sera from patients with MG. We expressed the N-terminal ECDs of the b (amino acids 1–221; ... subunit and the c ⁄ e subunits and the other between the second a subunit and the d subunit [4]. The c ⁄ e and d subunits play a major role in shaping...

Ngày tải lên: 30/03/2014, 10:20

... developments on the theoretical side layed the foundation of the field, such as metabolic control analysis [4,5] and biochemical systems theory [6]. In the 1980s, the development of extreme currents and elementary ... in describing and interpreting the effects of ethanol stress. In particular, the ratio between the kinetic constants associated with ethanol productio...

Ngày tải lên: 14/02/2014, 14:20

... C (1989) The limits of the DNase I-sensitive domain of the human apolipoprotein B gene coincide with the locations of chromosomal anchorage loops and define the 5¢ and 3¢ boundaries of the gene. ... Since then there has been an explo- sion of papers on the multitude of chromatin modifica- tions and the factors that can either create or recognize them. We now ha...

Ngày tải lên: 14/02/2014, 18:20

... grants from the Scientific Fund of the Ministry of Education, Science and Culture of Japan (G.T.); the Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical ... regulation of signal cascades and the physiological and pathological roles of miRNAs. Hence, further investigations aiming to elucidate the mechanisms...

Ngày tải lên: 14/02/2014, 19:20

... ATP-dependent manner [20]. Next, one strand (the passenger strand) of the miRNA is removed from the RLC, whereas the other strand (the guide strand) remains in the complex to form a mature RNA-induced ... both the BTG4 gene and the miR-34b ⁄ c polycis- toron [28]. Thus, miR-34b ⁄ c expression may be regulated by both the promoter of the host gene and the promoter i...

Ngày tải lên: 14/02/2014, 19:20

... part of the host defenses against infection and injury, but also contributes to the initiation and progression of atherosclerosis [103,104]. The response-to-injury hypothesis proposed that endothelial ... summarize the current understanding of miRNA function in the heart and outline details of what is known about their puta- tive targets. In addition, we review several...

Ngày tải lên: 14/02/2014, 19:20