Báo cáo khoa học: Transcription factors Sp1 and C⁄EBP regulate NRAMP1 gene expression ppt
Báo cáo khoa học: Transcription factors Sp1 and C⁄EBP regulate NRAMP1 gene expression ppt
... Sp1 and C ⁄ EBP regulate NRAMP1 transcription
FEBS Journal 275 (2008) 5074–5089 ª 2008 The Authors Journal compilation ª 2008 FEBS 5089
Transcription factors Sp1 and C
⁄
EBP regulate NRAMP1
gene ... that C ⁄ EBP and Sp1
factors regulate NRAMP1 expression during myeloid
differentiation.
Discussion
This study identified cis-acting sequences in the
NRAMP1 pro...
Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... acid synthase by pharma-
cologic or genetic means leads to an increased malonyl-CoA level and sup-
pression of food intake and adiposity. Conversely, the ectopic expression
of malonyl-CoA decarboxylase ... hypothalamus is sufficient to pro-
mote feeding and adiposity. Based on these and other findings, metabolic
intermediates in fatty acid biogenesis, including malonyl-CoA and long-...
Tài liệu Báo cáo khoa học: Binding of N- and C-terminal anti-prion protein antibodies generates distinct phenotypes of cellular prion proteins (PrPC) obtained from human, sheep, cattle and mouse doc
... regulation and
expression, as full-length and truncated isoforms of di-,
mono- and nonglycosylated proteins are only detect-
able with antibodies recognizing the C-terminal region
and produce altered expression ... SAF34 and P4
strongly stained the di-glycosylated band, and mAbs
6H4, SAF60, SAF70 and SAF84 showed the highest
staining with the overlapping bands of nonglycosyla...
Tài liệu Báo cáo khoa học: "Subgrammars, Rule Classes and Control in the Rosetta Translation System" ppt
...
derivation trees.
M-GENERATOR(d) = ~,.f
{ t I 3b•
B:d=b
andt=b }
U { t ] 3tl, ,t., dl d.,Ri:
d = R,<dl, ,d.> and
t~ • M-GENERATOR(dl) and
t. • M-GENERATOR(d.) and
t • F,'(tl ...
ce
=
[ce, l and
((D~ = D and u = t and A = false) or
(D2, u, true) • CF_,-PARSER(GI, ce,, D, t) and
A = true) }
U { (D~, u, A) I B
ce,:
ce = {ce,} and
((D~ = D and u =...
Báo cáo khoa học: D-strand perturbation and amyloid propensity in beta-2 microglobulin ppt
... D-strand into two halves. Middle: cartoon representation of the D53P mutant with a shorter D-strand and an extended
and protruding CD loop. Right: monomeric wild-type b2m displays a regular D-strand. ... MHC I (MHC) and the secondary structures of fibrillar b2m (AMY) predicted by Debelouchina et al. [19]. b-strands C, D and E
are labeled as ssC, ssD, and ssE, respectively. The CD an...
Báo cáo khoa học: "Using Large Monolingual and Bilingual Corpora to Improve Coordination Disambiguation" ppt
... Pattern
dairy and meat English: production of dairy and meat h of w
1
and w
2
production English: dairy production and meat production w
1
h and w
2
h
(ellipsis) English: meat and dairy production w
2
and ... meat
asbestos and English: polyvinyl chloride and asbestos w
2
h and w
1
polyvinyl English: asbestos , and polyvinyl chloride w
1
, and w
2
h
chloride English: as...
Báo cáo khoa học: "Correlation between ROUGE and Human Evaluation of Extractive Meeting Summaries" pptx
... between
ROUGE and human evaluation of extractive meeting
summaries and focus on two issues specific to the meet-
ing domain: disfluencies and multiple speakers. Both
human and system generated summaries ... Infor-
mative Coverage (IC): S2 and S9; Informative Relevance
(IRV): S3 and S8; and Informative Redundancy (IRD):
S4 and S7.
4 Results
4.1 Correlation between Human Evaluatio...
Báo cáo khoa học: Flavogenomics – a genomic and structural view of flavin-dependent proteins ppt
... cofactors are generally employed by enzymes
to enable a wide and diverse range of biochemical
transformations necessary for all aspects of life. Some
of these cofactors, such as vitamin B
12
and ... FMN
and FAD is based on their redox-active isoalloxazine
ring system, which is capable of one-electron and two-
electron transfer reactions and, most importantly, of
dioxygen activation [...
Báo cáo khoa học: Transcription of mammalian cytochrome c oxidase subunit IV-2 is controlled by a novel conserved oxygen responsive element pptx
... mut
and P
Sp1 proximal mut
(Table 1) were used for
site-directed mutagenesis with the GeneEditor site-directed
mutagenesis kit (Promega), according to the supplier’s pro-
tocol.
Transfection and ... Hercules,
CA, USA). The oligonucleotide primers P
ORE
,P
ORE mut
,
P
Sp1
,P
Sp1 mut
,P
Sp1 19bp
,P
Sp1 19bp mut
and Punspecific com-
petitor, and the 15 primer mixes containing mu...
Báo cáo khoa học: Transcription factor specificity protein 1 (SP1) and activating protein 2a (AP-2a) regulate expression of human KCTD10 gene by binding to proximal region of promoter pot
... 46.9%,
whereas overexpression of Sp1 increased the promoter
activity by 58.3%. The expression of endogenous
KCTD10 was downregulated 1.9-fold by Sp1 silenc-
ing, and upregulated 12.0-fold by Sp1 overexpression.
Western ... bound
the Sp1 or AP-2a sites, and worked in the basal
state to regulate KCTD10 transcription, respectively.
Roles of Sp1 and AP-2a in the regulation of...
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