Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot
Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot
... inhibition by interaction with SAFB1 /2 FEBS Journal 27 6 (20 09) 5 21 2 – 522 7 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 522 7 The enzymatic activity of SR protein kinases 1 and 1a is negatively affected ... (µg) 12 34 5 6 12 3456 12 345 6 12 34 12 34 12 3 4 56 66- 45- 35- 25 - 11 6- 66- 45- 35- 25 - 12 2 Fig. 2. Effect o...
Ngày tải lên: 30/03/2014, 01:20
Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx
... Governments through TSR-088-97, and CZE 00/33, by the Ministry of Education, Youth and Sports of the Czech Republic (LN 00A1 41) , by grants no. 20 4/ 01/ 025 4, 20 4/ 01/ 10 01, 20 6/03/D0 82, 309/ 02 /14 79 and MSMT 11 310 0003 ... 0.07 11 .28 ± 0. 72 I390–S6 01 21 2 3.50 ± 0.07 0.57 ± 0.08 5 .22 ± 1. 08 L354–P588 23 5 2. 95 ± 0.05 0.88 ± 0.03 11 .36 ± 0.48 L35...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: The antibiotic activity of cationic linear amphipathic peptides: lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes doc
... 6 .25 6 .25 6 .25 LK15(W14)(3.6) 1. 56 3 . 12 6 .25 6 .25 6 .25 6 .25 DnsLK15(3.6) 3 . 12 6 .25 12 .5 12 .5 12 .5 12 .5 DnsLK19(3.6) 50 50 R R R R DnsLK 22( 3.6) 25 50 10 0 25 25 25 LK16(W15)(3.0) 0.78 12 .5 12 .5 ... 6 .25 6 .25 6 .25 Scr-LK15(W14) 3 . 12 12 .5 R 10 0 10 0 10 0 DnsLK9 (2. 0) 6 .25 6 .25 R 50 10 0 50 DnsLK 11( 2. 0) 12 .5 25 R R R R DnsLK15(W14) (2. 0)...
Ngày tải lên: 23/03/2014, 17:21
Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx
... Glu 1 12 -Arg2 71 IIB-IVB CO 117 -Arg276 CO 120 -Arg277 – IIA-IIB Asp39-Arg 118 Asp96-Arg1 21 Asp 92- Arg 117 IVB-IVC Arg276-Asp280 Arg277 2 81 Arg276-Asp280 25 60 A. Hofmann et al. (Eur. J. Biochem. 27 0) Ó FEBS 20 03 Membrane ... III and IV. This figure was prepared with GRASP [36]. Table 2. Conservation of salt bridges. Anx(Gh1) Anx24(Ca 32) AnxA5 IE-IIA Arg80-Glu99 – – IIB-I...
Ngày tải lên: 17/03/2014, 03:20
Báo cáo Y học: Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues pptx
... (DN2) pGEX-rum1-DN13 pGEX-rum1-DN16 pGEX-rum1-DN 41 pGEX-rum1-DN74 pGEX-rum1-DC 52 pGEX-rum1-DC 81 pGEX-rum1-DC1 02 pGEX-rum1-DC130 pGEX-rum1-5A pGEX-rum1 -13 A pGEX-rum1 -16 A pGEX-rum1 -19 A pGEX-rum1-58A pGEX-rum1 -13 A16A pGEX-rum1 -13 A19A pGEX-rum1 -16 A19A pGEX-rum1 -13 A16A19A pGEX-rum1 -13 E19E pESP-rum1-WT (DN2) pESP-rum1 -13 E19E 3 5 12 K. Matsuoka et al. (Eur. J. Biochem. 26...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo khoa học: Long-term extracellular signal-related kinase activation following cadmium intoxication is negatively regulated by a protein kinase C-dependent pathway affecting cadmium transport ppt
... h in the presence of 2 l M CdCl 2 (Cd), pretreatment with 10 0 ngÆmL )1 PMA for 8 h followed by 2 lM CdCl 2 for 24 h (PMA then Cd), or treatment with 10 0 ngÆmL )1 PMA and 2 lM CdCl 2 for 24 h ... HEK293 cells were cultivated in DMEM and 10 % fetal bovine serum (Ø), in the presence of: 2. 5 l M GF 10 920 3X (GFX); 2 lM CdCl 2 (Cd), 2 lM CdCl 2...
Ngày tải lên: 23/03/2014, 06:20
Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx
... 23 .3 D266N 0.300 24 .0 Y269A 0 .26 5 29 .9 Q272R 0 .26 5 29 .9 D266N/Y269A 0.360 21 . 9 A271T/Q272R 0 .26 5 21 . 9 Y269A/A271T/Q272R 0.300 23 .8 D266N/Y269A/A271T/Q272R 0 .27 0 20 .0 Wild-type Sendai 0.330 14 8 N263D ... subtilisins. Enzyme Specific activity (katÆkg )1 ) a Casein Suc-Ala-Ala- Pro-Phe-MCA Wild-type ALP I 0 .29 0 26 .2 D 117 H 0 .23 7 21 . 2 V177T 0 .28 2 21 . 1...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: The specificity of alcohol dehydrogenase with cis-retinoids Activity with 11-cis-retinol and localization in retina docx
... ND k cat (min )1 )80±5 k cat/ K m (m M )1 Æmin )1 ) 10 000 ± 2 610 9-cis-retinal K m (l M ) 11 ± 2 4 .1 ± 0.9 21 ± 5 a 13 ± 2 15 ± 2 k cat (min )1 ) 1. 8 ± 0 .2 2.7 ± 0 .1 190 ± 25 a 17 ± 1 190 ± 5 k cat/ K m (m M )1 Æmin )1 ) 16 5 ± ... 660 ± 14 5 8980 ± 23 50 a 13 10 ± 21 5 12 800 ± 17 40 11 -cis-retinal K m (l M ) 15 ±3 16 ±4 21 3 26 ±7 28 ±3...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo khoa học: The transmembrane domain of subunitbof theEscherichia coli F1FOATP synthase is sufficient for H + -translocating activity together with subunitsaandc doc
... 20 04 doi :10 .11 11/ j .14 32 -10 33 .20 04.0 423 5.x b dimer seems to be a prerequisite at least for a proper assembly of the F 1 F O complex. A few years ago, the monomeric structure of a synthetic peptide ... 0.8 F O 14 .6 ac 4.7 b 2. 4 b 1) 34 (13 .3·) 0 .2 ac + b 11 .2 ac + b 1) 34 (3.3·) 5.4 ac + b 1) 34 (6.7·) 4.6 ac + b 1) 34 (13 .3·) 3.4 Ó FEBS 20 04 Function...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity pot
... Y380 Y6 62 W595 – – Pos2 L4 01 Y666 F476 E2 32 W 3 12 Pos3 W377 W659 – L1 41 – Pos4 I374 V656 V580 F139 a L178 Residues stabilizing the binding of the substrate in the specificity pocket Stb1 – R 125 R643 ... – Y256 Stb2 N470 N 710 R643 A270 I340 Oxyanion hole Oxa1 Y349 Y6 31 N555 W 114 Y147 Oxa2 Y 21 0 Y547 Y473 – – Residues responsible for the exopeptidase activity Exo1 F3...
Ngày tải lên: 23/03/2014, 13:20