Báo cáo khoa học: NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon ¨ Methanosarcina mazei Go1 pot
... studied the binding properties of NrpRII to the general transcription factors – TATA-binding protein (TBP) and the archaeal homolog of the eukaryotic general transcription factor TFIIB (TFB). MBP– NrpRII, ... Consequently, potential formation of a complex between NrpRI and NrpRII, as well as between NrpRII and general transcription factors, were invest...
Ngày tải lên: 29/03/2014, 21:20
... containing CRH or oxytocin [46] in the hypothalamus. The administra- tion of RFRP increases Fos expression in the hypotha- lamic paraventricular nucleus and in hypothalamic oxytocin neurons, and ... neuroendocrine and behavioral responses. Food intake also activates the brainstem and hypothalamus, resulting in the termination of meals and the induction of energy...
Ngày tải lên: 29/03/2014, 21:20
... R.&Yamamoto,Y.(2003)Dynamicinteraction between the D1 protein, CP43 and OEC33 at the lumenal side of photosystem II in spinach chloroplasts: evidence from light- induced cross-linking of the proteins in the donor-side ... investigated whether the PsbL and/ or PsbJ proteins offer a direct docking site for PsbP and PsbQ or whether PsbL and PsbJ only modulate the str...
Ngày tải lên: 30/03/2014, 13:20
Báo cáo khoa học: Co-operation of domain-binding and calcium-binding sites in the activation of gelsolin pptx
... repeated domains; six in the case of gelsolin itself, adseverin and villin, and three in capG, fragmin and severin (for a review, see [2]). The binding of calcium to gelsolin and to actin bound gelsolin ... for the various Calcium- binding sites so that IG1 is the type I binding site within G2 and IIG6 is the type II binding site within G6. Type I binding sites are coo...
Ngày tải lên: 31/03/2014, 01:20
Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf
... shifts the ratio between the strength (indica- ted by the thickness of the curved arrows) of the cis and trans interactions in favor of the latter. An increase in the trans inter- action results in ... domains, similarly to the situation found in the chicken beta-globin cluster. In this minireview we survey mechanisms and factors that may be involved in m...
Ngày tải lên: 20/02/2014, 01:20
Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of transcription factors ppt
... tissue. These compounds bind to two different intracellular proteins, namely FK506- binding protein (FKBP) and cyclophilin, and the drug–protein complex then binds to the interface of the calcineurin ... chronic in ammation of the joints. Both genetic and environmental factors are involved in the pathogenesis leading to joint destruction and ultimately dis- ability. In...
Ngày tải lên: 18/02/2014, 18:20
Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt
... residues in the flanking helices and loop are conserved compared with EF-hand III in CaM and the STIM1 EF-hand, such as position 8 in the loop, )8, )5, )1 in the E helix and +4, +5 in the F helix, which ... proposed Ca 2+ - coordinating ligands in italic) was inserted into the host pro- tein CD2 domain 1 between residues S52 and G53 with three Gly at the N-t...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Molecular dynamics structures of peptide nucleic acidÆDNA hybrid in the wild-type and mutated alleles of Ki-ras proto-oncogene ppt
... to interrupted stacking, fluctuating nature of the hydro- gen bond and water organization in the vicinity of the mismatch might be the contributing factors for the increase in free energy and diminished stability ... mismatch brings about signifi- cant reduction in adjacent base stacking in PD wt compared to PD mut . On the other hand, stacking at the AC(6–7) step i...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae pot
... PtdIns(5)P, PtdIns(3,4)P 2 and PtdIns(3,5)P 2 with the strongest binding to PtdIns(5)P (Fig. 1). The ORD domain showed a very similar lipid binding pattern as the full- length protein. While the ... structures. At 10 min, punctate staining diminished and vacuolar staining in- creased, and finally punctate staining was almost lost with predominant vacuolar staining at 30 min. Co...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: "Transparent combination of rule-based and data-driven approaches in a speech understanding architecture" pot
... transcribed and an- notated the data using a simple Java-based tool, randomly selecting 75% of it for use in training and keeping the rest for testing. During the course of the project, we routinely ... stored, and the inverse substitution is then applied on the output semantic atoms. 3.2 Writing and maintaining hand-coded rules ALTERF includes a pair of simple tools in...
Ngày tải lên: 08/03/2014, 21:20