Báo cáo khoa học: "What is the Minimal Set of Fragments that

Báo cáo khoa học: "What is the Minimal Set of Fragments that Achieves Maximal Parse Accuracy?" potx

... there may be several distinct derivations that generate the same parse tree. The probability of a parse tree T is thus the sum of the probabilities of its distinct derivations. Let t id be the ... the chart. 4 What is the Minimal Subtree Set that Achieves Maximal Parse Accuracy? 4.1 The base line For our base line parse accuracy, we used the no...

Ngày tải lên : 23/03/2014, 19:20

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Báo cáo khoa học: Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa potx

... information about the molecular mechanism of these pathologies. The study of GPCRs is also of outstand- ing pharmacological interest, as this family of recep- tors is involved in a wide variety of physiological ... The G51A, G51V and G89D mutants were studied in the context of the folding and packing of the TM domain together with other adRP mutations in the...

Ngày tải lên : 22/03/2014, 16:20

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Báo cáo khoa học: "WHEN IS THE NEXT ALPAC REPORT DUE" ppt

... tations. Traditionally, the start of intensive work on machine translation is taken as being a memorand~n of Warren Weaver, then Director of the Natural Sciences Division of the Rockefeller Foundation, ... themselves had begun to see that the enpi- rical approach was unsatisfactory. The European projects begun in the early 1960's at Grenoble and Milan refl...

Ngày tải lên : 24/03/2014, 01:21

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Báo cáo khoa học: What determines the degree of compactness of a calcium-binding protein? pdf

... based on the charges of the two EF-hand domains, and the other comprising a novel procedure that is based on linker average hydrophilicity. The linker consists of the residues that connect the domains. The ... PtICL9 (< 1% of the protein length). However, the length of the linker in the set of proteins considered in the present study is approxima...

Ngày tải lên : 30/03/2014, 02:20

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Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc

... is composed of residues 25–540. The overall structure of the model of IPU and the mutated residues in this study are shown in Fig. 3. To elucidate the mechanism of the substrate recognition of IPU, ... al. suggested that Glu179 is the general acid catalyst of pK a 5.9, and that the adjacent Glu180 is negatively charged, raising the p K a of the genera...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: "Methods for the Qualitative Evaluation of Lexical Association Measures" doc

... -best list (the precision) is computed. Another measure of goodness is the proportion of TPs in the base data that are also contained in the -best list (the re- call). While precision measures the ... We distinguish between two classes: (1) Characteristics of the set of candidate data employed for collocation identiﬁcation: (i) the syntactic homogeneity of th...

Ngày tải lên : 20/02/2014, 18:20

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Báo cáo khóa học: Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using ﬂuorescence spectroscopy pptx

... noticed that the dynamics of W242 in the protein is almost as large as that of W242 in the isolated peptide sequence P196–267 [16]. This strongly suggests that this part of the protein is highly ... information mainly on the dynamics of this region of the protein. This residue is probably widely accessible to the solvent in AC as shown by the maximum wave...

Ngày tải lên : 07/03/2014, 15:20

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Báo cáo khoa học: Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4 docx

... site of Six1 and Six4, suggesting that the DNA-binding speciﬁcity of Six1 is distinct from that of Six4. This underlies the differential regulation of common target genes by Six1 and Six4. Fur- thermore, ... binding sites of Six1 that exceed in number those of Six4 in the promoter region. Although the expression proﬁle of Slc12a2 has not been precisely analysed i...

Ngày tải lên : 07/03/2014, 17:20

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Báo cáo khoa học: Bacitracin inhibits the reductive activity of protein disulﬁde isomerase by disulﬁde bond formation with free cysteines in the substrate-binding domain pptx

... diminish the immunoblot signals for bacitracin at the site of PDI (Fig. 4C). These data support the view of a robust covalent PDI–bacitracin interaction. We hypothesized that the thiazoline ring of ... ring of bacitracin A (937.33). Negative ion mode CID-TOF ⁄ TOF MS analysis of the same precursor yielded the corresponding signature peaks (m ⁄ z 1404.88, 1438.82 and 14...

Ngày tải lên : 14/03/2014, 23:20

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Báo cáo khoa học: Intrabodies against the EVH1 domain of Wiskott–Aldrich syndrome protein inhibit T cell receptor signaling in transgenic mice T cells potx

... antigen. Therefore, large-scale libraries and extensive screening are required for the selection of the antigen-speciﬁc antibody fragments. On the other hand, the antibody fragments isolated ... further the function of the WASP- EVH1 domain in the TCR signaling pathway, we developed transgenic (Tg) mice that express intrabodies that speciﬁcally bind to the WASP-EVH1...

Ngày tải lên : 16/03/2014, 14:20

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