Báo cáo khoa học: Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence doc

... v 16 ðA10Þ Tracing 13 C in the pentose phosphate pathway R. J. Kleijn et al. 4982 FEBS Journal 272 (2005) 4970–4982 ª 2005 FEBS Revisiting the 13 C-label distribution of the non-oxidative branch of the pentose phosphate ... kinetic mechanism of the enzymes transketolase (EC 2.2.1.1) and transaldolase (EC 2.2.1.2). Based upon the ping-pong mechanism,...

Ngày tải lên: 23/03/2014, 15:21

... subset was made of only 11 targets and included 24, 7, 2 and 1 GOF, GOP, GOC and BIND annotations, respectively. Because of the sparseness of the data, the analysis was limited to GOF functional assignments ... to the assessor. After the experiment was concluded, we revisited the data collected and reassessed the results, taking into account the methods used. We...

Ngày tải lên: 30/03/2014, 10:20

... define the core of the protein’s N state [21]. For the T domain, these were the center of TH5 and TH8, and the N-terminal half of TH9. All a-helices (TH1, 3, 4, 5’, 6, 7 and the remaining parts of TH5 ... in the N state and the evolution of the overall structure of the protein in the MG state. This degree of resolution is unprecedented for the T do...

Ngày tải lên: 16/02/2014, 09:20

... specificity of the interaction. The lack of effect of the diphosphate nucleotide indicates that, following inorganic phosphate release, the ADP-bound ABCG2 R482G isoform adopts a conformation capable of ... evidence for an interaction between the two domains is the ability of numerous substrates and modulators of ABCG2 (and the R482G isoform) to stimulate the...

Ngày tải lên: 18/02/2014, 18:20

... RT-PCR to study the tissue-specific use of each promoter. We show the translation initiation site of isoform 2 and different intracellular distribution of isoforms 1 and 2, and discuss the regulatory ... secreted from cells. Hence, the pro- moter use of the KLK11 gene appears to link to the splicing pathway of KLK11 mRNAs and to regulate the trafficking of...

Ngày tải lên: 19/02/2014, 06:20

... each other). The value (the sign) of a cycle is the product of the values (the signs) of its steps. The sign o f the magnitude of a Ôminus combined autoinfluence path of order pÕ equal those of the ... The absolute magnitude of a combined autoinfluence path is the product of all the rates divided by the product of all the concentrations of its species...

Ngày tải lên: 19/02/2014, 16:20

... the scale of the Bard’s genera- tivity, and the quality of its insights. 5 Empirical Evaluation The vastness of the web, captured in the large- scale sample that is the Google ngrams, means the Jigsaw ... instances of the patterns “as ADJ and * as” and “as * and ADJ as” from Google, noting the combinations that are found and their frequencies. These frequ...

Ngày tải lên: 20/02/2014, 05:20

... improving the understanding of the recognition results. On the other hand, there were four level-down cases. Three of these cases were caused by the misdetection of errors in the SSC procedure. The ... arbitrary candidates, when one of their Error-Parts includes the other, and their frequencies are the same value, the candidate whose Error-Part includes the...

Ngày tải lên: 20/02/2014, 18:20

... between the cytoplasmic surfaces of myoblast and myotube NPCs and a correlation between the copy number of Nup358 and the NPC structure. Furthermore, small interfering RNA- mediated depletion of Nup358 ... attention. The general architecture of the NPC is evolutionarily con- served in all eukaryotes and consists of filaments on the cytoplasmic surface and spoke...

Ngày tải lên: 06/03/2014, 01:20

... from the parser to map parser constituents to the 5Ws. First the Who, When, Where and Why were ex- tracted, and then the remaining pieces of the sen- tence were returned as the What. The goal ... developed for the monolingual 5W task and not modified to handle MT. They used hand-crafted rules on the output of the latent annotation parser to extract the 5Ws....

Ngày tải lên: 08/03/2014, 00:20