Báo cáo khoa học: Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR pptx
Báo cáo khoa học: Identification, structure and differential expression of novel pleurocidins clustered on the genome of the winter flounder, Pseudopleuronectes americanus (Walbaum) ppt
... (1997) The role of CCAAT/enhancer-binding protein a and a protein that binds to the activator -protein- 1 site in the regulation of liver- specific expression of the winter flounder antifreeze protein ... degeneration of the sequences upstream of the pseudogenes made it impossible to predict the locations of the first introns and exons of Y1, Y2andY3. An align...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo khoa học: Identification, characterization and activation mechanism of a tyrosine kinase of Bacillus anthracis docx
... measurement of the equilibrium binding constant K a , the enthalpy of complex forma- tion (DH) and the complex stoichiometry of a protein protein interaction without the need for modification of the proteins ... where the presence of McsA enhances the autophosphorylation of McsB several-fold. We studied the binding pattern and the thermodynamic aspects of thi...
Ngày tải lên: 23/03/2014, 06:20
Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... to be protein domains impor- tant in the functioning of these transcription factors. The gene organiza- tions of zebrafish t-bet and foxp3 were identical to those of the human genes, with the second ... whether these cytokines are produced by CD4 + CD25 + Foxp3 + T reg or whether they induce the production of these cytokines from another population of cells [20]. To dat...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Identification, sequencing, and localization of a new carbonic anhydrase transcript from the hydrothermal vent tubeworm Riftia pachyptila docx
... of the CA D. melanogaster sequences and, on the other hand, the other D. melanogaster sequences more closely related to the CAVI vertebrate isoforms (CAa, CAb and D. melano- gaster-3) or to the ... trophosome-specific proteins. We demonstrated the existence of carbonic anhydrase transcripts, a protein endowed with an essential role in generating the influx of CO 2 required...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Identification of differentially expressed genes of the Pacific oyster Crassostrea gigas exposed to prolonged thermal stress docx
... folding of cytoskeletal proteins that are actively synthesized and ⁄ or renatured under these conditions. The upregu- lation of all of these chaperones confirms the severity of the thermal stress under ... constitutive isoforms of HSP70 are synthesized in the gills and mantle of C. gigas [26]. The expression level of the constitutive forms increases after thermal stre...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers ppt
... to quantify the amount of recovered protein owing to the presence of a high molar excess of BSA remaining in the buffer. Therefore, a fixed aliquot of the protein was incubated with the indicated ... con- firmed the nature of this protein (data not shown). Moreover, the spectrum reported in the figure showed the occurrence of a series of signals that were no...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx
... showing the presence of the tetraphosphorylated isoform, revealed a more extensive post-translational modification of the amni- otic fluid protein. Because the process can be the con- sequence of a ... by the amniotic fluid pro- tease and suggest that not only the degree, but also the position of the phosphate groups influence the process. As for the other IGFBPs,...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase pdf
... previously [18]. To assess the role of the S ⁄ Ts in the regulation of GIRK1 via PKA in a manner that is unbiased by the eventual contributions of the other subunits in a het- erooligomer, the corresponding ... in the present study). We conclude that the failure of these seven mutations to abolish protein phosphorylation was a result of other protein kinases mask...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Identification of multiple isoforms of the cAMP-dependent protein kinase catalytic subunit in the bivalve mollusc Mytilus galloprovincialis potx
... investigate the possible existence of different isoforms of the PKA C-subunit in the sea mussel M. galloprovincialis. Results Separation of different isoforms of the C-subunit In order to demonstrate the ... not scattered over the whole sequences, but rather limited to a particular region of the proteins. On the other hand, the presence of a peak at 1605.8 Da was...
Ngày tải lên: 07/03/2014, 06:20
Báo cáo khoa học: Identification and characterization of a nuclear receptor subfamily I member in the Platyhelminth Schistosoma mansoni (SmNR1) pot
... SmRXR1(Glu251-Asn376) in vitro. DNA binding of a protein containing 20 amino acids at the 5¢ end of the DBD, the DBD and the 40 amino acids at the 3¢ end of the DBD of SmNR1 (Ile247-Ser372) and SmRXR1 ... [7–9,11–14]. The precise length of the D domain was not deter- mined due to the highly divergent helices 1–2 in the LBD. However, the DBD terminates at amin...
Ngày tải lên: 07/03/2014, 11:20