Báo cáo khoa học: Subunit S5a of the 26S proteasome is regulated by antiapoptotic signals pot
Báo cáo khoa học: Subunit S5a of the 26S proteasome is regulated by antiapoptotic signals pot
... Regulation of subunit S5a of the 26S proteasome FEBS Journal 274 (2007) 2815–2831 ª 2007 The Authors Journal compilation ª 2007 FEBS 2831 Subunit S5a of the 26S proteasome is regulated by antiapoptotic ... regulation of the human S5a gene, we used PCR to isolate 1.2 kb of HeLa genomic DNA upstream of the first exon of the A B C D E F 24h 48h...
Ngày tải lên: 23/03/2014, 09:20
Báo cáo khoa học: Subunit composition of the glycyl radical enzyme p-hydroxyphenylacetate decarboxylase doc
... suppres- sion of the endogenous microflora and therefore may play an important role in the progression of the disease. The formation and tolerance of p-cresol by C. difficile as the end product of tyrosine ... activity of 7 UÆmg )1 . Preliminary results suggest that phosphorylation of the small subunit is responsible for the change of the oligomeric state. The...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Subunit sequences of the 4 · 6-mer hemocyanin from the golden orb-web spider, Nephila inaurata Intramolecular evolution of the chelicerate hemocyanin subunits pot
... 69.1–76.2% of their amino acids, with the a subunits being the most conserved and the b subunits the least conserved proteins (Table 2). The similarity scores of nonorthologous subunits is in the range ... and f,ande and g.TheC. salei hemocyanins group with the g -subunit of N. inaurata, while the hemocyanin subunit 6 of the scorpion Androctonus australis (AauHc...
Ngày tải lên: 08/03/2014, 08:20
Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx
... not enhance the autolysis of mGFP–calpain 7 in cultured cells. On the other hand, overexpression of FLAG– IST1 DMIM1,2 suppressed the autolysis. This observation might be explained by regarding IST1 ... apparently supporting the former possibility. However, it is also possible that IST1 acts on the sub- strate rather than on the protease. To investigate fur- ther whether...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf
... concomitant loss of the electron density of the loop region between b3 and b4 near the Thr- binding site are observed. The mechanism of regulation by Thr is discussed on the basis of the crystal structures. ... subunits [4–6]. AK of the a 2 b 2 type is encoded by in-frame overlapping genes, so that the amino acid sequence of the b -subunit is identical...
Ngày tải lên: 18/02/2014, 08:20
Báo cáo khoa học: Interaction analysis of the heterotrimer formed by the phosphatase 2A catalytic subunit, a4 and the mammalian ortholog of yeast Tip41 (TIPRL) ppt
... the PP2A holoenzyme is the trimeric A:B:C complex. The num- ber of B-type subunits is still growing with new members continuously being discovered. The subunit composition of the holoenzyme determines ... Subsequently, the GST–PP2Aca:His–TIPRL complex was incubated with His–a4 and the GST–PP2Aca:His–a4 complex was incubated with His–TIPRL. Binding of His–TIPRL to th...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Knock-out of the chloroplast-encoded PSI-J subunit of photosystem I in Nicotiana tabacum PSI-J is required for efficient electron transfer and stable accumulation of photosystem I pot
... accumulation of PSI In the absence of PSI-J, the steady-state accumulation of PSI is reduced by % 20%, as evidenced by the esti- mates of Chl ⁄ P700, the immunoblotting analysis of thylakoid ... the right hand side the actual Northern blot). (D) Immunoblot analysis of PSI complexes from wild-type and DpsaJ plants. The panel on the left is the stained gel,...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: Inactive forms of the catalytic subunit of protein kinase A are expressed in the brain of higher primates potx
... Identification of novel splice variants of the human catalytic subunit Cbeta of Formation of novel PKA C subunits by exon skipping A. C. V. Larsen et al. 260 FEBS Journal 275 (2008) 250–262 ª 2007 The Authors ... Autophosphorylation of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem 267, 25174–25180. 10 Yonemoto W, McGlone ML & Taylor SS (1993) N...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: Functional characterization of the maltose ATP-binding-cassette transporter of Salmonella typhimurium by means of monoclonal antibodies directed against the MalK subunit pot
... Most of the residues constitu- ting the epitope recognized by 2F9 are located on the same site but at the bottom part of the C-terminal domain. The only moderate effect of MalT on binding of 2F9 ... correspond to the position of the indicated residue in the E. coli MalK protein (see Fig. 1A). Please note that in Fig. 7B, the epitope of 5B5 is located on th...
Ngày tải lên: 31/03/2014, 09:20
Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... of the ligands, OD2 of Asp165, NE2 of His79 and NE2 of His169, formed an equatorial plane. The other protein ligand, NE2 of His31, bound to the metal, in the company of a water oxygen, from the ... [26]. These findings lead to the hypothesis that Fe-bound ApeSOD mimics the product-inhibited form and the shift of Tyr39 sup- presses the release of the peroxide...
Ngày tải lên: 14/02/2014, 22:20