Báo cáo khoa học: Non-hydrolytic functions of acetylcholinesterase The significance of C-terminal peptides pptx
Báo cáo khoa học: Non-hydrolytic functions of acetylcholinesterase The significance of C-terminal peptides pptx
... MINIREVIEW Non-hydrolytic functions of acetylcholinesterase The significance of C-terminal peptides Susan A. Greenfield, Martina Zimmermann and Cherie E. Bond The Institute for the Future of the Mind, ... up to the basal forebrain. Despite the heterogeneity in transmitters, these different nuclei all have the common feature of sending diffuse projec- tions to...
Ngày tải lên: 23/03/2014, 07:20
Tài liệu Báo cáo khoa học: Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft doc
... A comparison of the structure of the unli- ganded cathepsin B with the structure of the proenzyme, its complexes with chagasin and stefin A shows that the magnitude of the shift of the occlud- ing ... 1) between stefin A and the different enzymes is the average distance between the centre of mass of CA atoms of the stefin molecule and the centre of mass...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Bone morphogenetic proteins in the early development of zebrafish pptx
... change the preference of site utilization; and (c) promotion of the dissociation of Chordin cysteine-rich (CR)-containing fragments from the ligand. They suggest that the first of these three is the ... Smad4). The complexes move into the nucleus and act as regulators of transcription. The activity of BMP is regulated by the binding of extracellular inhibitors....
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx
... torque of 112 pNÆnm, the arrows show the beginning (t ¼ 1ns)andtheend(t¼ 23 ns) of the forced rotation. With 56 pNÆnm torque, the relaxation of the system was calculated during the last 8 ns of the ... the C-terminal portion of c, thus allowing for unimpaired rotation of the remainder of c.Furthermore, the calculations suggested the very end of c to be...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: A point mutation in the ATP synthase of Rhodobacter capsulatus results in differential contributions of DpH and Du in driving the ATP synthesis reaction pptx
... respectively. The data points have been fitted with arbitrary functions. (B) An enlarged view of (A), showing only the data obtained in the absence of Du.(C)Theratioof the best-fitting functions and of the ... in the absence of a Du,as shown in Fig. 3 C. In the presence of a Du, the difference between the two strains was twofold over the entire DpH range tested....
Ngày tải lên: 21/02/2014, 03:20
Tài liệu Báo cáo khoa học: Unfolding and aggregation during the thermal denaturation of streptokinase pptx
... over the unfolding transition of SK domain A. The enthalpy of the aggregate per mol of monomer unit (177 kJÆmol )1 ) lies between the enthalpies of the native state (the reference state) and the ... character- ization of the thermally induced aggregation of SK using a variety of techniques. The results provide us with some of the properties of these high m...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer pdf
... which indicate that the approach may be applicable to the treatment of a wide range of human cancers. This minireview summarizes the available data on these compounds and the challenges posed ... representative of the totality of the single-stranded overhang, and which may be important for these ligands being able to differentiate telomeric quadruplexes from others in the...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Trigger factor interacts with the signal peptide of nascent Tat substrates but does not play a critical role in Tat-mediated export pptx
... accele rated in the absence of TF probably by the disclosure of a more direct cotranslational targeting pathway to the Sec translocon [3]. Perhaps, the proofreading activity of the Sec t ranslocase ... To investigate whether this interaction is functionally relevant for the export of Tat p roteins, we monitored the effect of the intracellular TF level on the efficie...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "A Formula Finder for the Automatic Synthesis of Translation Algorithms" docx
... encountered, the program specifies the truth values of the variables in D r for the given values of i and j. The program then evaluates the truth value of D r in terms of the truth values of the ... translated of the oscilla- tions of the voltage of the trigger . . . rather than by the smoother inverted construction . . . of the oscilla- tion...
Ngày tải lên: 16/03/2014, 19:20
Báo cáo khoa học: Transcript profiling during the early development of the maize brace root via Solexa sequencing pot
... The development of the DGE system enables the sequencing of total cDNA for the derivation of an accurate measure of gene expression, both individually and comprehensively, and the discovery of ... category in the brace root tissue. For the rest of the categories, the tran- script abundances in the brace root were higher than that in the primary root. In the...
Ngày tải lên: 22/03/2014, 17:20