... de-stained for 1-2 hours. Measurement of MMP-8, MMP-9, and TIMP-1 activity MMP-8, -9 and TIMP-1 activity were quantified using ELISA-based activity assays (F8M00, F9M00, DTM100; R and D systems, Minneapolis, ... and MMP-9:TIMP-1 Activity in Pediat-ric ALI Since TIMP-1 normally provides negative regu-lation to MMP-9 in tissue compartments, we exam-ined TIMP-1 activity and MMP-9:TIMP-1 activity ra-tios ... MMP-9:TIMP-1 activity ratios during days 0-10 correlated with subjects who exhibited more rapid disease resolution within our study population. Table 2: MMP-9 activity, TIMP-1 activity, and...