Gene Therapy - Tools and Potential Applications by Francisco Martin Molina Contributors ppt

... orders@intechopen.com Gene Therapy - Tools and Potential Applications, Edited by Francisco Martin Molina p. cm. ISBN 97 8-9 5 3-5 1-1 01 4-9 moved rapidly by phagocytosis or by trapping in fine capillary ... re‐ Non-Viral Delivery Systems in Gene Therapy http://dx.doi.org/10.5772/52704 19 Gene Therapy - Tools and Potential Applications h...

Ngày tải lên: 17/03/2014, 21:20

... a de - ciency in the enzyme a- L -iduronidase (IDUA), and is char- acterized by skeletal abnormalities, hepatosplenomegaly and neurological dysfunction. In this study, we used a late gen- eration ... for its biosafety and allows the production of high-titer HIV-derived vector stocks. In addition, this late-generation gene transfer construct con- tains the polypurine tract (PPT) ,...

Ngày tải lên: 24/03/2014, 04:21

... net of taxes and subsidies, and suit- ably adjusted for internal transport costs to a location in a country. The export parity price is the net-of-taxes -and- subsidies price that export- ers would ... of supply and demand change. Real prices re- fer to prices of goods and services that reflect changes in the underly- ing conditions of supply and demand, but that do not reflect the...

Ngày tải lên: 30/03/2014, 18:20

... Polymer). 2. N-hydroxybenzotriazole (HOBt). 3. 2-( 1H-Benzotriazole-1-yl )-1 ,1,3,3-tetramethyluronium hexafluorophosphate (HBTU). 4. N-_-N-¡-di-Fmoc-L-lysine (AnaSpec, San Jose, CA). 5. N,N-diisopropylethylamine ... Ac-LARL-LRAL-LRAL-LRAL-NH 2 16 4 Hel KLLK-LLLK-LWKK-LLKL-LK 18 7 Hel61 LLK-LLLK-LWKK-LLKL-LK 17 6 Cationic _ -Helical Peptides 13 HindIII insert of the plasmid PGV-C (Toyo In...

Ngày tải lên: 11/04/2014, 09:59

... N,N-(2-chloroethyl)(2-mesyloxyethy1)aminobenzoyl- L -glutamic acid; 5'-DFUR, 5'-deoxy-5-fluorouridine; EO9,3-hydroxy-5-aziridinyl-1-methyl-(1H-indole-4,7-dione)-propenol;FIAU, 1-( 2'-deoxy-2-fluoro-b-D- arabinofuranosyl )-5 -iodouracil; ... ganciclovir; HM-1826, N-(4-b-glucuronyl-3 nitro-benzyloxy-carbonyl)-doxorubicin; MTX, methotr- exate; 6-TG, 6-thioguanine; ZD2767, 4-[...

Ngày tải lên: 11/04/2014, 10:33

... family. The elucida- tion of its crystal structure complexed with choline revealed a novel left-handed bb-3-solenoid fold formed by the stacking of six loop-b-hairpin structures, corres- ponding to ... com- pounds for C-LytA. Titration of the near-UV CD sig- nal of the protein with choline confirmed the presence of high-affinity and low-affinity binding sites [20,21] (Fig. 2). However, only...

Ngày tải lên: 19/02/2014, 05:20

... size- toilet Stool withholding / Retention Painful Defaecation Stool Consistency Iowa criteria √ √ - √ - - - Rome II √ - - - - - √ Working group √ - - √ - √ √ PACCT √ √ √ √ √ √ - ... Causes, Diagnosis and Treatment, Edited by Anthony G. Catto-Smith p. cm. ISBN 97 8-9 5 3-5 1-0 23 7-3 Constipation – Causes, Diagnosis...

Ngày tải lên: 30/03/2014, 23:20

... Introduction Gene therapy is a promising approach to treat intractable and refractory diseases at the genetic level. Basically, in gene therapy, target gene expression is induced by delivering foreign genes. Downregulation ... WZ, Dong CY. Tumor-targeted gene therapy using Adv-AFP-HRPC/IAA prodrug system suppresses growth of hepatoma xeno‐ grafted in mice. Cancer Gene Ther...

Ngày tải lên: 23/03/2014, 14:20

... into second-generation adenoviral vectors. These vectors, which included [E 1-, E2b- ]ADGFP&hBMP4, [E 1-, E2b-]ADhBMP6, and [E 1-, E2b- ]ADGFP&hBMP6, were validated by PCR, RT-PCR, and Southern ... Vector System ( [E 1- ,E2b-]AD) [3] was used for construction of human BMP second-generation adenoviral vectors ( [E 1-, E2b- ]ADhBMP6, [E 1-, E2b-]ADGFP&hBMP4, a...

Ngày tải lên: 31/10/2012, 17:08