Báo cáo Y học: Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice pdf

... response to western-type diet. Specifically, we found that apolipoprotein E3 knock -in mice fed western-type diet for 24 weeks became obese and developed hyperglycemia, hyperinsulinemia, hyperleptin- emia, ... LDLr )/) mice do not become excessively obese, and do not develop hyperglycemia and glucose intolerance in response to western-type diet. In our experiments, we stu...

Ngày tải lên: 17/03/2014, 17:20

... multiparity, previous abortion, previous cesarean section are frequently associated with placenta previa. They are accounted as risk factors of excessive bleeding and peripartum hysterectomy, even ... difference. And also these two groups showed no significant difference in maternal diseases such as endometriosis, myoma and incidence of myomectomy performed simultaneously durin...

Ngày tải lên: 25/10/2012, 10:56

... studies that are useful include α-fetoprotein (AFP) level, HCV genotype and RNA level. The AFP is widely used in screening of HCC, while HCV genotype and RNA level can later guide the treatment ... treatment. Besides genotypes 1, 2 and 3, other genotypes were not representative in the above mentioned studies, but in general, genotypes 4, 5 and 6 are thought to respond mo...

Ngày tải lên: 02/11/2012, 09:51

... virological responses to these treatments. Comparing to HCV treatment, the frequency needed for follow-up HBV DNA measurement is less defined during HBV treatment. However, it is recommended whenever ... should be monitored regularly. The interval of follow-up visits may vary depending on regimen and duration of the HBV treatment. For instance, those on IFN therapy may need to be mo...

Ngày tải lên: 03/11/2012, 09:41

... 355 the challenge of being able to select the thinnest suture, especially the one with non-absorbable material, pos- sibly non-filamentous, easy to be tied, and easily and painlessly removed. ... permeability of the three different suture threads examined in this study was tested using bro- moethylene blue stain. The results showed that the polyurethane suture threads were the...

Ngày tải lên: 03/11/2012, 11:52

... the molecules within individual cells using appropriate fluorescent probes [36–38]. The green fluorescence inside cells indicated that FITC-Yb 2 -Tf entered cells and may have been located in cytoplasm ... (Fe 2 -transferrin) complex into K562 cells. The results demonstrate that the complex of Yb 3+ -transferrin complex was recognized by the transferrin receptor and that the transferrin-r...

Ngày tải lên: 08/03/2014, 09:20

... additional repetitive extragenic palindromic element (REP-element) between the prpB and prpC coding sequence. The DNA sequence of the intergenic region containing the REP-element is shown in the upper ... identified as methylcitrate [1]. Further investigations revealed other enzymes necessary for a functional methylcitrate cycle. The enzymes, however, were only partially characterized and...

Ngày tải lên: 17/03/2014, 10:20

... formation and conformational disease are underlined. Existing models for the mechanism need to be tested by experiment. The kinetic and energetic bases of the process are reviewed. The main controversial ... diseases, many of which are hitherto incurable, and secondly, because it remains to be explained in physical terms (energetically and structurally). The process leads to fi...

Ngày tải lên: 17/03/2014, 23:20

... histidine kinases may either be the consequence of a decrease in the histidine kinase activity, or, alternatively, of an increase in an intrinsic autophosphatase activity present in the BvgS and EvgS proteins ... respiratory diseases in man and animals, respectively [3,4]. It controls expression of a huge virulence regulon including the genes encoding the pertussis and adenylate...

Ngày tải lên: 17/03/2014, 23:20

... NLSinv) were cultured, and the proteins were purified as described previously [45]. Nuclear import assay Digitonin permeabilized HeLa cells were prepared essen- tially as described by Adam et ... coding sequence into mammalian expression vector pEGFP-C1 (Clontech). To introduce deletions into the NLD-I sequence of nPTB we used a two-step PCR method. In the first step we used the following...

Ngày tải lên: 18/03/2014, 01:20