Báo cáo khoa học: The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors ppt
Báo cáo khoa học: The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors ppt
... autoradiographs of the amplified products and the quan-tification of the bands is shown in the bottom panels. Rb and Sp1 mRNA levels were determined from the ratio of the intensities between the Rb or Sp1 and ... inhibitors. We report that the expression of retinoblastoma and Sp1 is increased by low concentrations of CDK inhibitors inChinese hamster ovary (CHO) K1 and human cells by amechanism involving transcriptional ... that the inhibition of CDK activityincreases the expression of Rb and Sp1. Fig. 1. Effects of UCN-01 on the levels of Rb and Sp1 protein. (A), (B) Dose–response of the effect of UCN-01 on the levels...
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Báo cáo khoa học: "THE EXPRESSION OF LOCAL RHETORICAL RELATIONS IN INSTRUCTIONAL TEXT*" pdf
... of the expression. In (4a), the action is being performed by the reader which leads to the use of a present tense, relational clause. In (4b), on the other hand, the action is performed by ... affects the form of expression. Consider the fol- lowing examples: (4a) When the 7010 is installed and the battery has charged for twelve hours, move the OFF/STBY/TALK [8] switch to STBY. The ... anal- ysis of these examples and a presentation of the statistical evidence for each result can be found in Vander Linden (1992a). PURPOSES One important factor in the choice of form is the availability...
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Báo cáo khoa học: 15-Deoxy D12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor c in human erythroleukemia cells ppt
... treatment of cardio-vascular disease associated with diabetes mellitus and is entirely consistent with the growing recognition of the importance of PPARc and its agonists in the regu-lation of those ... sense primers. The following lists the identities of the Prm3 gene fragments and the correspond-ing plasmids generated in the vector pGL3Basic (annotatedpGL3b) and the identity of the specific ... cardiovascular disease in patients with diabetesmellitus and in animal models of diabetes is associatedwith both the increased synthesis and action of TXA2,most likely due to increased TP expression...
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Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf
... [10].COX-1 is generally considered the housekeepingenzyme that is constitutively expressed and involved in the maintenance of haemostasis. COX-2, by contrast, is the inducible isoform that is expressed ... present on the lumenal surfaces of the ER and on the inner and outermembranes of the nuclear envelope [14].Within the last decade, many groups have studied the relocation of cPLA2-a following ... package.AcknowledgementsThis work was funded by the British Heart Founda-tion and the BBSRC. We thank Dr C. J Edgell for the gift of the EA.hy.926 cells and Dr R. Williams for the cPLA2-a–GFP plasmid. We...
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Tài liệu Báo cáo khoa học: The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3¢ UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes pdf
... SJS260, and the creation of the ARE II ⁄ ARE IV double mutant used primers SJS261 and SJS262. The mutagenesis of ARE I and III introducedHindIII restriction sites and so the creation of the pTET-GLO3¢ ... beyond the endpoint of the experiment (based on the composite curve of three separate experiments presented in Fig. 1), demon-strating the high stability of this transcript. The half-life of the ... binding activity to the ‘extendedARE’, despite the fact that it contributes to mRNAstability. Whether this is a consequence of the limita-tion of the REMSA approach or the influence of alternative...
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Tài liệu Báo cáo khoa học: The Saccharomyces cerevisiae vacuolar acid trehalase is targeted at the cell surface for its physiological function docx
... Ath1 at the cell surface and the role of the single transmem-brane (TM) domain at the N-terminus of this proteinwere investigated. The functional localization of Ath1was further assessed by constructing ... afterco-transformation of yeast cells with the mCherry–His3-MX6_ATH1 PCR cassette together with plasmids path1DN, and selection of the recombinant plasmid in the absence of both uracil and histidine. Similarly, ... 474–845 and 849–904) that together may constitute the catalyticdomain of Ath1 [22]. To map the minimal domain of Ath1 that allows the secretion of this protein, variousDNA fragments of ATH1...
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Tài liệu Báo cáo khoa học: "The Thesaurus in Syntax and Semantics" docx
... 4. The only way of defining the notion of a the- saurus, in practice, is by reference to the famous work of Roget, Thesaurus of English Words and Phrases (Longmans, Green and Co. 5. ... language, and then, distinct from this, an interlingual analysis. The monolingual grammar is of the kind normally produced by descriptive linguists, except that it is only for the operators of each ... strengthened the case for coding this program to go through the com- puter by using the very general mathematical system known as lattice theory. (The use of lattice theory for the analysis of...
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Tài liệu Báo cáo khoa học: "The Distributional Inclusion Hypotheses and Lexical Entailment" pdf
... first tested the empirical validity of the hypotheses. Then, we demonstrated how the hypotheses can be leveraged in practice to improve the precision of automatic acquisition of the entailment ... sim(w,v) is an initial approximation of the similarity space by Lin’s measure, WS(f) is a set of words co-occurring with feature f, and N(w) is the set of the most similar words of w by Lin’s ... generality. Their conjecture is that the majority of the features of the more specific word are included in the fea-tures of the more general one. They define the fea-ture recall of w with respect...
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Tài liệu Báo cáo khoa học: The unique sites in SulA protein preferentially cleaved by ATP-dependent Lon protease from Escherichia coli ppt
... that the activity of the enzymewas inhibited by a low concentration of SDS (about 50%inhibition in the presence of 0.0025% SDS). On the otherhand, an extensive degradation of SulA3±169 by the ... relatively preferred at the P1sites. On the other hand, the cleavage in the absence of ATP was very much slower, especially in the centralregion, than in the presence of A TP. The central regionwas ... during 120 min of incubation. On the other hand, nodegradation of MBP was observed either in the presence orin the absence of ATP under the conditions used. Theseresults indicated that the enzyme...
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Báo cáo khoa học: The male seahorse synthesizes and secretes a novel C-type lectin into the brood pouch during early pregnancy pdf
... C-terminal end of the CRD, and the third is found towards the N-terminal end and spans the firststrand; the latter is lacking in the short (i.e. 115 resi-due) form. All of the cysteines forming these ... young and the father whichregulates the levels of synthesis and secretion of theseproteins. To date there is little, if any, information on the ways in which such communication occurs duringthis ... disulphide bridges are com-mon in the long form (approximately 130 residues),one of which spans from the end of the first helix to the end of the CRD, the second is shorter and locatedat the...
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Từ khóa: chuyên đề điện xoay chiều theo dạngNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hươngTăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ