Báo cáo khoa học: Identification and expression of the first nonmammalian amyloid-b precursor-like protein APLP2 in the amphibian Xenopus laevis ppt

... encoding the KPI domain and the lack of a second heparin-binding domain [3,4,13,26]. Comparative analysis of the Xenopus and mammalian APLP2 proteins Comparing the amino acid sequences of the ... The luminal portions of all superfamily members contain conserved zinc-binding [13,14], heparin- binding [14] and collagen-binding domains [15]. Further- more, a GTP-bin...

Ngày tải lên: 16/03/2014, 16:20

... IL, interleukin; IL-1Ra, interleukin 1 receptor antagonist; ICE: interleukin 1b converting enzyme; IL)18 BP, interleukin 18 binding protein; IFN, interferon; c-IP10, interferon gamma induced protein ... Cloning and expression of interleukin-18 binding protein. FEBS Lett. 445, 338–342. 32. Novick, D., Kim, S.H., Fantuzzi, G., Reznikov, L.L., Dinarello, C.A. & Rubinstein, M. (1999...

Ngày tải lên: 16/03/2014, 16:20

... domain of t-bet, the STAT protein inter- action domain, STAT protein all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-finger domain, leucine-zipper domain and ... is implicated in other protein protein interactions, a STAT protein DNA-binding domain and an SH2 domain, which binds phosphorylated tyrosine residues in the cont...

Ngày tải lên: 16/02/2014, 09:20

... representing the 5¢- and 3¢-UTRs are shown in white in the genomic gene and the cDNA. Intron size in bp, domain size in bp and domain size in amino acids are indicated at the bottom of each schematic ... experiments showing SmSmad1B protein interactions. The following cri- teria were utilized in this table for designating the extent of the protein inter...

Ngày tải lên: 18/02/2014, 16:20

... com- pared to the wild type and other sip(ba) mutant strain (data not shown). The yields of protein s ecreted after 24 h of growth in TBY medium as well as the protein changed banding pattern were ... A BLAST search of the nucleotide sequence of the ampli®ed DNA fragment revealed the presence of three ORFs, the deduced proteins having 70, 77, and 67% identity...

Ngày tải lên: 21/02/2014, 03:20

... SmNR1(Ile247-Ser372) and SmRXR1(Glu251-Asn376) in vitro. DNA binding of a protein containing 20 amino acids at the 5¢ end of the DBD, the DBD and the 40 amino acids at the 3¢ end of the DBD of SmNR1 (Ile247-Ser372) ... (containing 20 amino acids at the 5¢ end of DBD, DBD and 40 amino acids at the 3¢ end of DBD), SmRXR1 and SmRXR1(Glu251-Asn376) (con- ta...

Ngày tải lên: 07/03/2014, 11:20

... clarified in detail and could play a key role in the detoxification processes. In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activity involved in the ... important in deter- mining the level of Bcp2 protein. Similar results are observed for genes and related proteins involved in oxidative stress in other mic...

Ngày tải lên: 07/03/2014, 12:20

... these fusion proteins run at the expected height, proving that no internal methionine was used as initiation start in the translation of the wild type mRNA of XN73 and that the XN73 protein runs with ... M., Fujisawa,H.,Kleihues,P.&Walter,G.(2001)Reducedexpres- sion of the Aa subunit of protein phosphatase 2A in human gliomas in the absence of mutations...

Ngày tải lên: 08/03/2014, 08:20

... that triafestin-1 and triafestin-2 inhibit the activation of the kallikrein–kinin sys- tem by inhibiting the reciprocal activation of factor XII and prekallikrein, and subsequent release of bradykinin. Binding ... pathway. Triafestin inhibits FXII and PK reciprocal activation and bradykinin generation To investigate inhibition of the kallikrein–kinin system by triafe...

Ngày tải lên: 16/03/2014, 05:20

... different. Therefore, we investigated the relative binding proper- ties of these two types of HSA. We investigated the binding of L(small)-Trp as an endogenous ligand which binds to site II, and of cefazolin ... synthesis and release at the brain, and that might contribute to the pathogenesis of cisp- latin-induced emesis. These findings indicate that the state of C...

Ngày tải lên: 16/03/2014, 13:20