Báo cáo khoa học: Fatty acid composition of chylomicron remnant-like particles influences their uptake and induction of lipid accumulation in macrophages pot

... 2006) doi:10.1111/j.1742-4658.2006.05552.x The in uence of the fatty acid composition of chylomicron remnant-like particles (CRLPs) on their uptake and induction of lipid accumulation in macrophages was studied. CRLPs containing triacylglycerol ... Fatty acid composition of chylomicron remnant-like particles in uences their uptake and...

Ngày tải lên: 16/03/2014, 12:20

... binding of ACP to the docking site followed by a conformational change in ACP proposed to inject the acyl chain into the sub- strate-binding pocket [32]. If a similar mechanism is involved in ... all point to the orientation of H333 and its hydrogen bond donor properties as being the cornerstone of obtaining and ⁄ or retaining residual decarboxylase activity. The emerging pictur...

Ngày tải lên: 19/02/2014, 08:20

... N-terminal domain of Rv2212 could also contain a tunnel for the uptake and binding of fatty acid molecules, we attempted modelling (Fig. 6B,C). The results demon- strate that fatty acid binding ... protein constituent at any pH (see below), we favour pH-independent binding of the fatty acids to Rv2212. The kinetic bases of the fatty acid and pH-sensing responses o...

Ngày tải lên: 30/03/2014, 10:20

... predominantly of dihydroxylated C 18 -LCBs, of which the majority are unsaturated: 76% dienine-con- taining and 17% sphingenine-containing sphingolipids, compared with 7% sphinganine-containing sphingoli- pids. ... assignment of function of TpdesB as a sphinganine D 8t -desaturase, we examined the sphingolipid LCB composition of T. pseudonana. This indicated that the diatom sphi...

Ngày tải lên: 20/02/2014, 01:20

... regulatory element binding proteins (SREBP; reviewed in [81]) and that activation of the sterol regulatory element binding protein-2 isoform is involved in the induction CYP4F2 by statins [80]. Parallel ... cytokines are involved in regula- tion of the CYP4F enzymes levels during in amma- tion. The pro -in ammatory cytokines interleukin-1b, interleukin-6 and tumor necrosis fa...

Ngày tải lên: 22/03/2014, 16:21

... contain large amounts of proteins we can assume that a germinated A. fumigatus spore will use these proteins as carbon source. In that case, the amino acids isoleucine, valine and methionine become degraded, ... determined as an average of three samples each. Effect of co-metabolism of amino acids on polyketide synthesis The amino acids methionine, valine and isoleucine were use...

Ngày tải lên: 23/03/2014, 15:20

... moieties of glycoproteins and glycolipids [7–10]. The use of endo-b-galactosidase has been expanded to detection of poly (N-acetyllactosamine) chains in a variety of complex glycoconjugates in addition ... pH 5.8 and an appropriate amount of the enzyme was incubated at 37 °C. Samples (each 50 lL) were taken at intervals (0, 5, 10, 15 and 20 min) during the incubation and...

Ngày tải lên: 31/03/2014, 07:20

... FEBS bean and soybean. When binding of arginine in the presence of tRNA was investigated, some changes in the binding architecture were observed [35], in that N(153:Y), in addition to interacting with ... December 2008) doi:10.1111/j.1742-4658.2009.06866.x l-Canavanine occurs as a toxic non-protein amino acid in more than 1500 leguminous plants. One mechanism of its toxici...

Ngày tải lên: 18/02/2014, 13:20

... recombinant protein accu- mulated intracellularly in a soluble form. On the other hand, when induced at 37 °C, almost all of the protein accumulated in an insoluble form. Recombinant pro- teins of ... consisting of an RNase H domain and an APase domain. The RNase H and APase activities of the full length SCO2299 protein depend on its N-terminal RNase H domain and C-ter- mina...

Ngày tải lên: 19/02/2014, 18:20

... acids resulting from the intestinal digestion of proteins [4,5]. Another example of the detection of the lack of an amino acid is metabolic adaptation to cope with epi- sodes of protein malnutrition. In ... the role of mTORC1 kinase in the regulation of gene expression by amino acid availability. The enrichment of amino acid- regulated genes according to their biolo...

Ngày tải lên: 07/03/2014, 03:20