Báo cáo khoa học: Structural and functional characterization of human Iba proteins ppt

... cross-linking efficiency of Iba1 and Iba2 or in the overall morphology of the generated filament bundles. Calcium affinity of Iba1 and Iba2 Homodimerization and actin binding of Iba1 and Iba2 were similar in ... presented here reveals functional simi- larities and differences between Iba1 and Iba2 . We investigated Ca 2+ binding and homodimerization of Iba1...

Ngày tải lên: 16/03/2014, 06:20

... that the PRTFDC1 proteins have lost their phosphoribosyl- transferase activity [10]. The structural characterization of numerous com- plexes of the human HPRT and several bacterial and protozoan ... authors. Studies of the human PRTFDC1 M. Welin et al. 4930 FEBS Journal 277 (2010) 4920–4930 ª 2010 The Authors Journal compilation ª 2010 FEBS Structural and functional...

Ngày tải lên: 15/02/2014, 01:20

... D and E + F), (b) a few hydrogen bonds, and a hydrophobic interaction between A + C, B + E and D + F, and (c) electrostatic forces in the central channel of the hexamer between B, C and F, and ... ª 2007 FEBS Structural and functional investigations of Ureaplasma parvum UMP kinase – a potential antibacterial drug target Louise Egeblad-Welin 1 , Martin Welin 2, *, Liya Wa...

Ngày tải lên: 18/02/2014, 16:20

... Isolation and characterization of adenovirus type 2 vertex capsomer (penton base). Virology 92, 125–138. 33 Pettersson U & Hoglund S (1969) Sructural proteins of adenoviruses. 3. Purification and characterization ... ionic strength of the solvent environment and ⁄ or presence of small organic compounds (dioxane and MPD) seems to favor formation of dodecahedra over i...

Ngày tải lên: 19/02/2014, 06:20

... describes the cloning and functional characterization of an AK gene from a genomic library of L. donovani as well as its expression and molecular characterization. Materials and methods Materials Plasmids ... transfer of the c-phosphate group from ATP to AMP, releasing two molecules of ADP. This study describes cloning and functional characterization of the gene en...

Ngày tải lên: 21/02/2014, 00:20

... long a-helices and a final b-strand, F, which protrudes from the core of the monomer and runs anti-parallel to the same strand of a second monomer, allowing for the formation of the dimer. The surface of ... last class of cagPAI proteins, and summarize what is known about them both from a molecular and structural point of view, as well as their putative physiological rol...

Ngày tải lên: 06/03/2014, 00:21

... 2004 Molecular and functional characterization of novel CRFR1 isoforms from the skin Alexander Pisarchik and Andrzej Slominski Department of Pathology and Laboratory Medicine, University of Tennessee ... isoform where exon 3 and exon 6 are spliced out (U16273); CRFR1d isoform where exons 6 and 13 are missing (AF180301); CRH-R1e with deletion of exons 3 and 4 (AF369651)...

Ngày tải lên: 07/03/2014, 15:20

... Here we confirm and extend earlier studies of these AAA-peroxins and give a further detailed functional analysis of their cassette structure and interaction. The interaction of Pex1p and Pex6p involves their ... biological function of Pex1p and Pex6p. A B Fig. 2. Two-hybrid interaction of Pex1p and Pex6p harboring point mutations of the WalkerA and B motifs of the...

Ngày tải lên: 07/03/2014, 16:20

... transcript. Expression and biochemical characterization of VBARP The predicted sizes of the proteins encoded by VBARP-L and VBARP-S are 69 and 49 kDa, respec- tively. To test this, C-terminal V5-tagged VBARP-L and ... Both VBARP-L and VBARP-S variants have high homology to PP2500 and ANKHD1 vari- ant 2. In this study we focus on the biochemical and functional characte...

Ngày tải lên: 07/03/2014, 21:20

... Comparative structures of CMP and UMP, and interactions between the cyto- sine moiety of nucleotide and various side chains of wild-type CMP kinase. (Upper) Chemical differences between CMP and UMP are ... [17]. Results Overproduction and molecular characterization of the modified variants of E. coli CMP kinase The wild-type and various modified forms (S36A, R110M, D132A...

Ngày tải lên: 16/03/2014, 10:20