Báo cáo khoa học: Induction of translationally controlled tumor protein (TCTP) by transcriptional and post-transcriptional mechanisms pot
Báo cáo khoa học: Modulation of glucocorticoid receptor-interacting protein 1 (GRIP1) transactivation and co-activation activities through its C-terminal repression and self-association domains pptx
... NRs and is influenced by ligand, cell type and the target gene promoter [3,4]. The mechanism by which DNA-bound NRs regulate transcription appears to involve the recruitment of co-regulatory proteins, ... homology, the nature of their downstream targets and the specific components of the transcriptional machinery remain unknown. The mechanisms by which the p160 co-activato...
Ngày tải lên: 07/03/2014, 12:20
Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx
... macrophages and white blood cells, and pro- moted by low-density lipoproteins (LDL) without adequate removal of fats and cholesterol from the macrophages by functional high-density lipoproteins (HDL). ... the expression of KLF4; although both HDL 2 and HDL 3 led to an induction of KLF4 in mRNA and protein levels in PBMC and PMA-differentiated THP-1 macrophages, the i...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx
... reproduce a process observed in some types of tumorigenesis. During the course of tumor progression, the ectodomain of E-cadherin can be detached by ma- trilysin and stomilysin-1, releasing an 80 kDaA ... aggregation and invasion of cells into type I collagen [10]. Furthermore, sE-cad sti- mulates the up-regulation of MMP-2, MMP-9 and MTI-MMP expression in human lung tumo...
Ngày tải lên: 19/02/2014, 05:20
Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx
... in the absence and presence of AA and the concentrations of prostanoids was measured in the cell culture supernatants by GC-MS. Figure 1A shows a dramatic induction of both PGE 2 and the stable ... of PGI 2 synthesis (bar graph) and on PPARb-LBD mediated transcriptional activity (bottom row). PPAR activities are shown as the average of triplicates and standard deviat...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Induction of raft-like domains by a myristoylated NAP-22 peptide and its Tyr mutant potx
... FEBS 1803 Induction of raft-like domains by a myristoylated NAP-22 peptide and its Tyr mutant Raquel F. Epand 1 , Brian G. Sayer 2 and Richard M. Epand 1,2 1 Department of Biochemistry and Biomedical ... chlo- roform ⁄ methanol (2 : 1) and the lipid deposited on the walls of a glass test tube by solvent evaporation with a stream of nitrogen gas. Last traces of solvent...
Ngày tải lên: 07/03/2014, 17:20
Tài liệu Báo cáo khoa học: Expression of poly(A)-binding protein is upregulated during recovery from heat shock in HeLa cells doc
... Re12 h Re24 h 20 30 40 0 10 HSP27 % of input % of input HSP70 Fig. 7. Coimmunoprecipitation of HSP2 7and HSP70 with PABP1 and eIF4G. Cells were subjected to heat shock and recovery as described in the legend to Fig. 1, and the ... Mosser DD & Bag J (2005) Induction of HSP70 expression and recruitment of HSC70 and HSP70 in the nucleus reduce aggregation of a polyal...
Ngày tải lên: 18/02/2014, 12:20
Tài liệu Báo cáo khoa học: Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme ppt
... Department of Molecular Biology, University of Copenhagen, Denmark Synthesis of dTMP by thymidylate synthase proceeds by the reductive methylation of dUMP, which is obtained via one of two parallel ... E138A trimer in complex with dCTP (grey) and dTTP (yellow, cyan and magenta). (B) Stereo- view of a superposition of one of the sub- units of the E138A variant of E....
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc
... kindly provided by Dr K. Shuai (University of California, Los Angeles). TMK-1 cells were cotransfected with 8.5 lg of TAM67 and 1.5 lg of pBabePuro by using the Lipofectamine reagent, and the transfected ... apoptosis by modulating the process of apoptosis [11–14]. Thus, we determined the effect of EGF on the levels of key antiapoptotic (i.e. Bcl-2 and Bcl-X L ) and...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Inhibition of pea ferredoxin–NADP(H) reductase by Zn-ferrocyanide docx
... [51,52]. The O of Ser90 and the S of Cys266 of pea FNR are close to N5 and O4 of the isoalloxazine, which are involved in hydride transfer. The hydroxy group of Ser90 could accept a hydrogen bond and thus ... for appropriate binding of the metal ion, which remains accessible from the exterior (Fig. 7B). Distances between the N5 and O4 of the flavin, O of Ser90, S of C...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Characterization of electrogenic bromosulfophthalein transport in carnation petal microsomes and its inhibition by antibodies against bilitranslocase docx
... acid free BSA and 20 mm Tris ⁄ HCl pH 7.5 at a final protein concentration of % 1mgÆmL )1 . Marker enzyme assays The level of purification of tonoplast and plasma mem- brane vesicles was evaluated by measuring ... immunization and bleeding of rabbits; to Silvia Zezlina for the affin- ity purification of antibody A from rabbit sera; to Dr Paolo Ermacora and Prof Giorgio Honse...
Ngày tải lên: 20/02/2014, 01:20