Báo cáo khoa học: Induction of translationally controlled tumor protein (TCTP) by transcriptional and post-transcriptional mechanisms pot
Báo cáo khoa học: Modulation of glucocorticoid receptor-interacting protein 1 (GRIP1) transactivation and co-activation activities through its C-terminal repression and self-association domains pptx
... NRs and is influenced by ligand, celltype and the target gene promoter [3,4]. The mechanism by which DNA-bound NRs regulate transcriptionappears to involve the recruitment of co-regulatoryproteins, ... homology, thenature of their downstream targets and the specificcomponents of the transcriptional machinery remainunknown.The mechanisms by which the p160 co-activatorsfunction in NR transcriptional ... 1122–1304,1305–1398, 1305–1462, and 1399–1462) fusion proteins or with GSTalone; bound proteins were eluted, separated by SDS ⁄ PAGE, and visualized by autoradiography. (C) The proteins for the GRIP1...
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Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx
... macrophages and white blood cells, and pro-moted by low-density lipoproteins (LDL) withoutadequate removal of fats and cholesterol from themacrophages by functional high-density lipoproteins(HDL). ... theexpression of KLF4; although both HDL2 and HDL3led to an induction of KLF4 in mRNA and protein levels in PBMC and PMA-differentiated THP-1macrophages, the increment level induced by HDL3was ... real-time PCR. (B) Protein levels of KLF4were determined by western blot. (C) mRNA levels of hSR-BI weredetermined by real-time PCR. (D) Protein levels of hSR-BIwere determined by western blot....
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Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx
... reproduce a process observed in some types of tumorigenesis. During the course of tumor progression,the ectodomain of E-cadherin can be detached by ma-trilysin and stomilysin-1, releasing an 80 kDaA ... aggregation and invasion of cells into type I collagen [10]. Furthermore, sE-cad sti-mulates the up-regulation of MMP-2, MMP-9 and MTI-MMP expression in human lung tumor cells, asreported by Noe and ... activation and results in uPA gene activation. siRNA-mediated knockdown of endogenousSrc-homology collagen protein (Shc) and subsequent expression of single Shcisoforms revealed that p46Shc and p52Shcbut...
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Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx
... in the absence and presence of AA and theconcentrations of prostanoids was measured in the cellculture supernatants by GC-MS. Figure 1A shows adramatic induction of both PGE2 and the stable ... of PGI2synthesis (bar graph) and on PPARb-LBDmediated transcriptional activity (bottom row). PPAR activities areshown as the average of triplicates and standard deviation.Raf induction of ... increase in thesynthesis and release of PGE2 and PGI2which wasmainly due to a strong transcriptional activation of theCox-2 gene (and to a lesser extent of PGIS and mPGES-1). Under the same experimental...
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Báo cáo khoa học: Induction of raft-like domains by a myristoylated NAP-22 peptide and its Tyr mutant potx
... FEBS 1803 Induction of raft-like domains by a myristoylated NAP-22peptide and its Tyr mutantRaquel F. Epand1, Brian G. Sayer2 and Richard M. Epand1,21 Department of Biochemistry and Biomedical ... chlo-roform ⁄ methanol (2 : 1) and the lipid deposited on thewalls of a glass test tube by solvent evaporation with astream of nitrogen gas. Last traces of solvent were thenremoved by evaporation ... targeting of myristoylated and palmitoyl-ated proteins. Biochim Biophys Acta 1451, 1–16.43 Gratzer WB (1970) Numerical values of the absorbances of the aromatic amino acids. In Handbook of Biochemis-try:...
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Tài liệu Báo cáo khoa học: Expression of poly(A)-binding protein is upregulated during recovery from heat shock in HeLa cells doc
... Re12hRe24h203040010HSP27% of input % of inputHSP70Fig. 7. Coimmunoprecipitation of HSP2 7and HSP70 with PABP1 and eIF4G. Cells were subjected to heat shock and recovery as describedin the legend to Fig. 1, and the ... Mosser DD & Bag J (2005) Induction of HSP70 expression and recruitment of HSC70 and HSP70 in the nucleus reduce aggregation of a polyala-nine expansion mutant of PABP1N1 in HeLa cells.Hum ... of mRNA translation by competing with PAIP1. Eukary-otic release factor 3 also interacts with PABP1, and facilitates termination of translation, and reinitiation by 40S ribosomal subunits, by...
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Tài liệu Báo cáo khoa học: Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme ppt
... Department of Molecular Biology, University of Copenhagen, DenmarkSynthesis of dTMP by thymidylate synthase proceeds by the reductive methylation of dUMP, which isobtained via one of two parallel ... E138Atrimer in complex with dCTP (grey) and dTTP(yellow, cyan and magenta). (B) Stereo-view of a superposition of one of the sub-units of the E138A variant of E. coli dCTPdeaminase in complex ... stochiometry of 1 : 1 of dTTP bound per subunit of dCTPdeaminase.Mutational analysis of amino acid residuesinvolved in dTTP regulation of dCTP deaminaseThe design of the mutant enzymes H121A and V122Gwas...
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Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc
... kindly provided by Dr K. Shuai (University of California, Los Angeles). TMK-1 cells were cotransfectedwith 8.5 lg of TAM67 and 1.5 lg of pBabePuro by usingthe Lipofectamine reagent, and the transfected ... apoptosis by modulating the process of apoptosis [11–14]. Thus, wedetermined the effect of EGF on the levels of keyantiapoptotic (i.e. Bcl-2 and Bcl-XL) and proapoptotic(i.e. Bad and Bax) proteins. ... action of EGF inTMK-1 cells. EGF increased the expression of the Bcl-XL protein, anantiapoptotic member of the Bcl-2 family, but not that of other anti (Bcl-2) or proapoptotic (Bad and Bax) protein...
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Tài liệu Báo cáo khoa học: Inhibition of pea ferredoxin–NADP(H) reductase by Zn-ferrocyanide docx
... [51,52].The O of Ser90 and the S of Cys266 of pea FNR are closeto N5 and O4 of the isoalloxazine, which are involved inhydride transfer. The hydroxy group of Ser90 could accept ahydrogen bond and thus ... forappropriate binding of the metal ion, which remainsaccessible from the exterior (Fig. 7B). Distances betweenthe N5 and O4 of the flavin, O of Ser90, S of Cys266, O of Glu306 and O of Tyr308 indicate ... NADPH oxidation catalyzed by FNR inthe presence of Fd or F ld was not affected by the presence of up to 1 mMZnSO4.The effect of equimolar concentrations of Zn2+ and ferrocyanide on diaphorase...
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Tài liệu Báo cáo khoa học: Characterization of electrogenic bromosulfophthalein transport in carnation petal microsomes and its inhibition by antibodies against bilitranslocase docx
... acidfree BSA and 20 mm Tris ⁄ HCl pH 7.5 at a final protein concentration of % 1mgÆmL)1.Marker enzyme assaysThe level of purification of tonoplast and plasma mem-brane vesicles was evaluated by measuring ... immunization and bleeding of rabbits; to Silvia Zezlina for the affin-ity purification of antibody A from rabbit sera; to DrPaolo Ermacora and Prof Giorgio Honsell (University of Udine) and Mr Fulvio ... protonelectrochemical potential generated both by theH+-ATPase and H+-PPiase [11]. By analogy, thismodel may also include the protein encoded by thett12 gene in Arabidopsis thaliana [12], a member of themultidrug...
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Từ khóa: Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Chuong 2 nhận dạng rui rochuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM