... likely to demonstrate an equivalentrole on ACMS by possibly recognizing its aldehydegroup (Fig. 1). Our observation is in agreement withwhat was observed for PfACMSD, where a significantincrease ... significant enzyme inhibition that wasfound to be exerted by intermediates of glycolysis(Table 1), a pathway imbalanced in diabetes, is intrigu-ing. Moreover, our structural data reveal that ... humanlymphocytes. Biosci Biotechnol Biochem 64, 1142–1146.10 Fernandez-Pol JA, Klos DJ & Hamilton PD (20 01) Antiviral, cytotoxic and apoptotic activities of picolinicacid on human immunodeficiency virus-1...