Sputum smear negative pulmonary tuberculosis: sensitivity and specificity of diagnostic algorithm docx

... RESEARCH ARTICLE Open Access Sputum smear negative pulmonary tuberculosis: sensitivity and specificity of diagnostic algorithm Hedwiga F Swai 1* , Ferdinand M Mugusi 2 and Jessie K Mbwambo 3 Abstract Background: ... diagnosis of pulmonary tuberculosis in patients with Human Immunodeficiency Virus (HIV) is complicated by the increased presence of sputum smear...

Ngày tải lên: 15/03/2014, 03:20

... development and validation, policy and clinical practice should be modifi ed to improve the diagnosis and management of smear- negative pulmonary tuberculosis. Rapid diagnosis and treatment of smear- negative ... diagnosis of smear- negative than smear- positive pulmonary tuberculosis has been reported, 36 perhaps because the diagnostic algorithm needs 11–3...

Ngày tải lên: 15/02/2014, 12:20

... were PCR-positive. The sensitivity and specificity of in-house PCR for diagnosis of smear- negative PTB were 75% (95% CI 62.6-85.0) and 35.9% (95% CI 27.2-45.3), respectively. The positive and negative predictive ... PCR assay for diagnosis of smear- negative TB using Lowenstein-Jensen (LJ) culture as the baseline test. Two hundred and five pulmonary TB (PTB) suspe...

Ngày tải lên: 15/03/2014, 03:20

... sensitivity and specificity of clinical algorithms Evaluation of a diagnostic algorithm for smear- negative pulmonary tuberculosis in HIV-infected adults P Saranchuk, A Boulle, K Hilderbrand, D ... accuracy of and reduction in diagnostic delay attributable to a clinical algorithm used for the diagnosis of smear- negative pulmonary tuberculosis (SNPTB) in...

Ngày tải lên: 29/03/2014, 03:20

Ngày tải lên: 06/03/2014, 04:20

... have smear- negative pulmonary and extrapulmonary tuberculosis. In the absence of rapid, simple, and accurate diagnostic tools for smear- negative pulmonary and extrapul- monary tuberculosis, diagnostic ... diagnosis and treatment of all cases of tuberculosis, including smear- negative pulmonary and extrapulmonary tuber- culosis. The existing guidelines f...

Ngày tải lên: 15/03/2014, 03:20

... of cases (10 HIV-positive and 19 HIV -negative) , alveolar injury in 32 (80%) of cases (13 HIV-positive and 19 -negative) , interstitial lesion in 15 (37.5%) of cases (8 HIV-positive and 7 -negative) , ... 10 (25%) of cases (4 HIV- positive and 6 -negative) , pleural effusion in 9 (22, 5%) of cases (3 HIV-positive and 6 -negative) , atelectasis in 4 (10%) of cases (...

Ngày tải lên: 22/03/2014, 18:20

... positive and HIV negative patients. Conclusion: Conversion rates of standard smear microscopy, fluorescence microscopy and culture did not differ between HIV positive and HIV negative pulmonary ... [15]. Conclusion Conversion rate of standard smear microscopy and fluorescence microscopy did not differ between HIV positive and HIV negative pulmonary tuberculosis pat...

Ngày tải lên: 15/02/2014, 12:20

... classified in old studies. Using the distinction of pulmonary tuberculosis into sputum smear- positive (smear- positive) and sputum smear- negative (smear- negative) cases, the most common classification ... because of the poor sensitivity of sputum smear and its dependence on factors such as the number of repeat smears[14].Yet,itiswellestablished that many smea...

Ngày tải lên: 29/03/2014, 03:20

... presentation and the lack of sensitive and rapid diagnostic tests. Considering the impact if misdiagnosis and risk of transmission to health care professionals, clinicians must maintain high level of ... morbidity and mortality. It will be important to develop and utilize novel, more sensitive and specic tests. Considering the serious impact of missed or delayed dia...

Ngày tải lên: 15/02/2014, 12:20