... The molecular basis of LAM revolves around four key ques-tions: What genetic factors contribute to LAM pathogenesis? Why does LAM occurexclusively in women? What is the cell of origin of LAM? ... Department of Pediatrics, University of Cincinnati School of Medicine and Cincinnati Children’s Hospital Medical Center, Cincinnati, OHMargaret W. Leigh, MD, Department of Pediatrics, University of ... MD, Department of Internal Medicine, University of Cincinnati School of Medicine, Cincinnati, OHEnid R. Neptune, MD, Department of Internal Medicine, John Hopkins UniversitySchool of Medicine,...