Báo cáo khoa học: NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube pptx

... NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube Caroline ... show that NBR1 interacts with two proteins; fasciculation and elongation protein zeta-1 (FEZ1), a P KCf interacting pro - te...

Ngày tải lên: 08/03/2014, 10:20

... receptor-associ- ated protein (RAP), and partially by the C1q -binding protein calreticulin, where inhibition experiments indi- cated that half of the binding sites on C1q for CD91 were shared with calreticulin ... share the property of binding the MASPs and therefore do not activate the complement cascade but function as opsonins. The lung surfactant proteins share...

Ngày tải lên: 06/03/2014, 01:23

... factor-jB (p65 and p50) and that the binding domain of Nucling is its amino-terminal region (amino acids 1–466) containing ankyrin repeats. Overexpression of Nucling prevents the translocation ... screening for the protein interacting with Nucling using NuclingDN as ‘bait’ [4]. Therefore, it is conceivable that Nucling is involved in several signal- ing pathways through inte...

Ngày tải lên: 16/03/2014, 04:20

... yeast colonies containing these plasmids are shown in (B) and (E) on SD plus L-histidine and adenine and (C) and (F) on SD lacking L-histidine and adenine. Evi1 binding proteins R. McGilvray et ... transformed with the combination of plasmids shown. The growth of single yeast colonies containing these plasmids are shown in (B) and (E) on SD lacking L-histi- dine and...

Ngày tải lên: 16/03/2014, 11:20

... dematin containing 84 amino acids of the core domain and complete headpiece domain mediated binding with the DH domain of human Ras-GRF2 (Fig. 1). In contrast, a bait construct containing only the ... association of Ras-GRF2 with dematin, an actin binding and bundling protein, provides a potential coupling mechan ism between Ras signaling a nd the a ctin cytoskeleton wi...

Ngày tải lên: 17/03/2014, 11:20

... plotted against the amount of the protein. The binding constant was calculated by determining the protein molar concentration at 50% binding efficiency [33]. Fig. 4. Simultaneous binding of PABP and ... nm and 5.9 nm, respectively. The IMP1 domain responsible for binding to the ARS IMP1 is a modular protein with two RRM type and four KH RNA binding domains. T...

Ngày tải lên: 23/03/2014, 10:20

... stabili- ties of interaction with the pre-60S complex and not inefficient binding to the column. In order to determine whether the Nop53p trun- cated mutants also bind RNA directly, in vitro RNA binding assays ... [31]. In order to determine whether Nop53p interacts with the pre-rRNA early during transcription, chromatin immunoprecipitation (ChIP) experiments were per...

Ngày tải lên: 30/03/2014, 04:20

... signatures in the sequences are present in both proteins, tyrosinases and catechol oxidases; these include the six histidine resi- dues involved in the binding of a pair of copper ions and other conserved ... in copper binding. Preceding the sixth histidine (H 3B according to the nomenclature used in [6]), at the end of the CuB -binding site, tyrosinase-like en...

Ngày tải lên: 19/02/2014, 07:20

... are no clashes of amino acid side chains in the core of the structure, and most mutations occur on the protein surface. The FAD binding groove is conserved with most ligand binding residues identical. ... upon cysteine exchange are the black appearance of the C30S protein and the orange colour of the C130S mutant. Changing the other cysteine within these pair...

Ngày tải lên: 17/03/2014, 10:20

... hydrophobic interactions in proteins [26]. Removing a methyl group in the protein hydrophobic core affects protein folding and decreases the protein stability in mutant proteins [27]. In PR, two ... Exploring the changes in PR due to binding of two different inhibitors will give insight into the mechanisms of resistance and help in the design of new inhibitor...

Ngày tải lên: 18/02/2014, 04:20