Báo cáo khoa học: Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans potx

... linear response of the detection technique. This supplementary material can be found in the online version of this article. Please note: Wiley-Blackwell is not responsible for the content or functionality ... TOP-containing construct than what was observed with the construct containing TOP alone. This is in good agreement with previous observations that the ARS slows the rate of tra...

Ngày tải lên: 18/02/2014, 12:20

... (solvent-exposed disulfide bonds) and GSSG promotes the formation of disulfide bonds in proteins, resulting in the formation of the native conforma- tion of a protein. Glutathione (c-GSH) contains a c-branched ... disulfide bonds, including mis-bridged disulfide bonds, two disulfide bonds, no disulfide bonds and native disulfide bonds, respectively, as confirmed by MALDI-TOF ⁄ MS analy- ses. Th...

Ngày tải lên: 06/03/2014, 00:21

... effect of amino acids on gene expression. Concerning the stimulation of gene expression by the presence of amino acids, only one gene, Pept 1, encod- ing a peptide transporter, was shown to contain ... representation of the influence of glutamine on the transcription of genes involved in intermediary metabolism. Table 5. Influence of glutamine on transcription factors involv...

Ngày tải lên: 07/03/2014, 00:20

... compilation ª 2006 FEBS which consist of intronic miRNAs in protein-coding transcripts [8,9]. Separation by splicing of the miRNA component from the 5¢ CAP-exon-EGFP-3 ¢ poly(A) component should ... processing of the pri- miRNA is relatively efficient even when the miRNA cassette is in an exon, but correspondingly that most of the marker protein expression is lost through degra-...

Ngày tải lên: 07/03/2014, 11:20

... years ago [4]. On the basis of this long period of co-evolution, there are some indica- tions that colonization by H. pylori could have been beneficial for their human carriers and this probably provided ... polarity, cell proliferation, actin-cytoskeletal rearrangements, cell elongation, disruption of tight and adherens junctions, pro-inflammatory responses and the suppression of apo...

Ngày tải lên: 14/02/2014, 19:20

... a reduction in the thermostability of their native states. Analysis of mRNA levels in this selection of variants suggests that the lower levels of secretion are due to post-transcriptional processes, ... and location of the mutations discussed in this study. The locations of the single-point mutations are shown on the structure of human wild-type lyso- zyme, defined by X-ray...

Ngày tải lên: 19/02/2014, 08:20

... reside only in the C-terminal por- tion (Fig. 3C). This discrepancy is particularly appar- ent for HP0527 that consists of almost 2000 residues, of which only 400 at the C-terminus correspond to VirB10 ... function of which is unknown, is often associated with VirB4. In certain bacteria, some of these components are absent. This is the case for the H. pylori ComB system where...

Ngày tải lên: 06/03/2014, 00:21

... was responsible for conceiving the study, data acquisition, analysis of the data, statistical analysis and drafting of the manuscript. BC was responsible for data acquisition, analysis of the ... severity classification was modified, since this classification is ade- quate for administration errors, but not entirely for prescription errors. An independent panel, consisting of one cl...

Ngày tải lên: 25/10/2012, 10:39

... patients displayed signs of pneumonitis and pneumonia upon arrival. Three patients presented with severe sinusitis. Microbiology identified a variety of common but also uncommon isolates that were often ... Psychoemotional responses further com- prised distress about injuries sustained, dissociation, optical, acoustical and olfactory intrusions and, in some cases, agita- tion. Discussion...

Ngày tải lên: 25/10/2012, 10:41

... the safety of patient care. We believe, however, that development of ‘a sense of professionalism’ is not a function of whether a shift is 30 hours or is 16 hours, but is a function of the ethical priorities ... [2]. Letter Effect of intern’s consecutive work hours on safety, medical education and professionalism Christopher P Landrigan, Steven W Lockley and Charles A Cze...

Ngày tải lên: 25/10/2012, 10:45