Báo cáo khoa học: Pharmacology of vascular endothelium Delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw pptx
Báo cáo khoa học: Pharmacology of vascular endothelium Delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw pptx
... hydrophilic pravastatin) at a concentration of 30 lm mobilize free cytoplasmic calcium [Ca 2+ ] i to 30–50% of that induced by Bk at a concentration of 10 nm. In the case of simvastatin and lovastatin, this ... [59]. In Langendorff’s preparation of guinea-pig heart, statins produce NO • -dependent vaso- dilatation of coronary vascular bed [59]. The precon- tracted bo...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden pdf
... domain-containing proteins and some 45 PX domain-containing proteins that presumably mediate most (but not all) of the downstream functions of PtdIns3P [29]. Additional PtdIns3P-binding proteins that ... certain variant pleckstrin homology domains such as the GLUE (GRAM-like ubiquitin-binding in EAP45) domain [32–34]. Intracellular localization of PtdIns3P The identification of...
Ngày tải lên: 06/03/2014, 01:23
Tài liệu Báo cáo khoa học: Effect of siRNA terminal mismatches on TRBP and Dicer binding and silencing efficacy pdf
... studied the relationship between the silencing efficiency of the siRNAs and their binding to the RNA-induced silencing complex loading complex proteins HIV transactivating response RNA-binding protein and ... function of TRBP in RNAi. Here, we have characterized the interactions of siRNAs that contain terminal mismatches with TRBP and Dicer, and determined the impact of t...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS ppt
... 274 (2007) 6269– 6276 ª 2007 The Authors Journal compilation ª 2007 FEBS 6271 dimethylation of Arg, monomethylation, dimethylation and trimethylation of Lys, acetylation and ubiquitina- tion of ... phosphorylation of Ser and Thr [16– 18]. Combinations of these modifications are suggested to constitute a ‘histone code’ that regulates the binding of protein complexes involved...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: His374 of wheat endoxylanase inhibitor TAXI-I stabilizes complex formation with glycoside hydrolase family 11 endoxylanases pptx
... xylose. In spite of the above, profound analysis of the speci- fic contributions of the amino acid residues at the interface of the enzyme–inhibitor interaction is lacking. Mutagenesis studies of a ... of the interaction with B. subtilis endoxylanase than the k on rate constants of the inter- actions with A. niger or T. longibrachiatum M2 endoxylanases. At...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Analysis of DNA-binding sites on Mhr1, a yeast mitochondrial ATP-independent homologous pairing protein potx
... compilation ª 2010 FEBS 1443 the reduction in the efficiency of FRET in the presence of the W71F or W165A mutants was not due to defects in the DNA-binding activities of these mutants. DNA-binding ... RIKEN SPring-8 Center, Hyogo, Japan Introduction Homologous DNA recombination is conserved in all organisms. In the nucleus, homologous recombination is involved in...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Modulation of nitric oxide-mediated metal release from metallothionein by the redox state of glutathione in vitro doc
... combination of tighter binding of cadmium than zinc in metallothioneins and the preference of zinc in the more flexible b-domain. In addition to the already described differences in flexibility of the ... of 100 : 1 and only insignificant amounts of cadmium being released at the highest ONOO – concentration. Even more interestingly, in contrast to the peroxyni...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx
... observed in Jurkat cells in response to SeV infection. ArgII is involved in the biosynthesis of natural poly- amines (putrescine, spermidine and spermine) through conversion of l-arginine into l-ornithine ... NF-jBin ArgII regulation. Our study is thus the first direct demonstration of the involvement of IRF-3 in ArgII regulation in response to virus infection. IRF-3 is...
Ngày tải lên: 07/03/2014, 21:20
Tài liệu Báo cáo khoa học: Development of a new method for isolation and long-term culture of organ-specific blood vascular and lymphatic endothelial cells of the mouse pdf
... aliquot of the transgene was introduced into E14.1 ESCs by electro- poration. ESCs expressing the transgene were selected by incubation for 7 days in medium containing a concentra- tion of G418 (Invitrogen) ... compilation ª 2008 FEBS 1991 substantial proportion of the cell population from the uterus (Fig. 3C) also stained positive for Lyve-1, indi- cating that cell populati...
Ngày tải lên: 18/02/2014, 17:20
Báo cáo khoa học: "Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial"
... the unnoticed changing of an already activated prescription of a continuous infusion medication. Since recent upgrading of the system every continuous infusion prescription change becomes immediately visible ... notation was properly filled in 69% of the patients in the C-U, whereas only 2% had an allergy notation in the charts of the PB-U. The only allergy error...
Ngày tải lên: 25/10/2012, 10:39