Báo cáo khoa học: VEGF gene expression is regulated post-transcriptionally in macrophages pdf

... regulation of VEGF in macrophages FEBS Journal 273 (2006) 732–745 ª 2006 FEBS No claim to original US government works 745 VEGF gene expression is regulated post-transcriptionally in macrophages Min Du 1 , ... its receptor interact intracellularly to regulate VEGF gene expression [48]. The mechanism of regulation of the macrophage VEGF receptor, VEGFR-1, is now...

Ngày tải lên: 07/03/2014, 12:20

... proteins, which in vertebrates, comprises of p65 (RelA), p50/p105, p52/p100, c-Rel and RelB [3]. Within resting cells, NF-jB is retained in the cytoplasm complexed to an inhibitor protein from ... necrosis factor a (TNFa)and interleukin-1b (IL-1b). Similarly, both TNFa and IL-1b strongly induced mRNA and protein expression of inter- cellular adhesion molecule (ICAM)-1 and in each ca...

Ngày tải lên: 07/03/2014, 15:20

... metabolism, in particular for flavonoid bio- synthesis, indicating the preferential expression of genes involved in flavonoid metabolism in red perilla. Of 24 green perilla-specific clones, in contrast, ... recombinant PfCHI1 protein was deter- mined in vitro using naringenin chalcone as the sub- strate. As shown in Fig. 8, the recombinant PfCHI1 protein could stereospecifically con...

Ngày tải lên: 23/03/2014, 07:20

... perivenous). Amino acid degradation Figure 3C demonstrates differences in expression of the genes encoding enzymes of histidine and serine ⁄ glycine catabolism. Three genes encoding enzymes of histidine catabolism, ... acids 2.3.3.8 oxaloacetate 4.1.1.32 gluconeo- genesis diacylglycerol diacylglycerol-P 3.1.3.4 APOC2 activation + 3.1.1.34 B Lipo- proteins Fig. 3. Zonal differences in e...

Ngày tải lên: 23/03/2014, 10:20

... domain binding motif in their C-termini. PDZ domains have been established as sites for protein–protein inter- action and play a central role in organizing diverse cell signaling assem- blies. In ... including clustering, targeting and routing of their binding partners [13–15]. PDZ target specificity is usually dependent on the extreme carboxyl-terminal amino acid sequence of the inter...

Ngày tải lên: 18/02/2014, 13:20

... lgÆmL )1 ) for 2 h results in significant increase in UCP2 expression (3.6-fold, P < 0.05). On the other hand, analysis of the kinetics of induction of UCP2 protein in MDP-treated macrophages revealed ... as brain mitochondrial carrier protein 1, BMCP1) have much lower sequence identity with UCP1 [2,3]. UCP1 is the best characterized of these proteins, mediating non-shivering th...

Ngày tải lên: 05/03/2014, 23:20

... of the hupTUV genes is below the detection limit or is missing in T. roseopersicina. Mutagenesis and homologous expression of the hupT and hupTUV genes In- frame deletion mutagenesis was used to ... transcription is r 70 -dependent in R. capsulatus [1]. This is in line with the observation that the putative r 54 interaction sites within the HupR ⁄ HoxA proteins are well conse...

Ngày tải lên: 16/03/2014, 23:20

... Gartenstadt in dem weis- sen Hochhaus in einem Eckzimmer." Thus, it is always possible to insert another definite locative element in a string before coming finally to the indefinite locative ... (2i). By inverting the se- quential numbering of the i-singlets obtained from i-quantification (but not the strings corresponding to the i-singlets), we obtain the order of generat...

Ngày tải lên: 16/03/2014, 19:20

... it is well established that NF-jB controls the transcription of a range of genes important for regulating in ammatory events in macrophages, including the expression of proinflammatory cytokines ... Karin M (2002) Missing pieces in the NF-kappaB puzzle. Cell 109 (Suppl), S81–S96. 16 Collins T & Cybulsky MI (2001) NF-kappaB: pivotal mediator or innocent bystander in atherogenesi...

Ngày tải lên: 23/03/2014, 04:20

... 1.5- fold induction in both cell lines, suggesting that their expression was regulated independent of Arnt. To confirm these findings, nine of the 50 up -regulated genes were selected for Q-PCR analysis. ... changes in hypoxia-induced gene expression by microarray analysis. By comparing quantitative PCR analyses of these nine genes in BpRc1 and hepa1c1c7 cells, we determined that...

Ngày tải lên: 23/03/2014, 06:20