Báo cáo khoa học: DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork docx

... (5¢-to3¢) A GGCTGCAGGTCGAC B CAGCAACGCAAGCTTG C GTCGACCTGCAGCCCAAGCTTGCGTTGCTG A- flap ATGTGGAAAATCTCTAGCAGGCTGCAGGTC GAC B -flap CAGCAACGCAAGCTTGATGTGGAAAATCTCT AGCA B-g1 CAGCAACGCAAGCTT B-g2 CAGCAACGCAAGCT B-g4 ... CAGCAACGCAAGCT B-g4 CAGCAACGCAAG A- b15 AGAGATTTTCCACAT A- b17 CTAGAGATTTTCCACAT A- b19 TGCTAGAGATTTTCCACAT D TGACAAGGATGGCTGGTGGGACTTAGCGTA E TACGCTAAGTCCCACCAGCCATCC...

Ngày tải lên: 07/03/2014, 10:20

... FEBS 88 Haraguchi K, Satoh K, Yanai H, Hamada F, Kawabu- chi M & Akiyama T (2000) The hDLG-associated pro- tein DAP interacts with dynein light chain and neuronal nitric oxide synthase. Genes ... [1] and code for an extremely con- served 10 kDa protein. The Chlamydomonas, Caenor- habditis elegans, Drosophila and mammalian LC8 orthologs share more than 90% identity. The two mam...

Ngày tải lên: 14/03/2014, 22:20

... CCATTCCAGgtgagtag 84 ctccgcagGCCGCGCCG 2 851 CTTCTCCCGgtgtgcac 403 gtccccagGCCGGATCA 364AATGTGAGgtaggaag 277 ctcctcagAAATGTGAG 4 172 CAACAAAGgtacatgc 1335 ctgtgcagGTACTGGTG 5 1028 A. Ray et al. ... of the SAF-1/MAZ/Pur-1 family, is expressed during inflammation Alpana Ray 1 , Srijita Dhar 1 , Arvind Shakya 1 , Papiya Ray 1 , Yasunori Okada 2 and Bimal K. Ray 1 1 Department of Veterinary P...

Ngày tải lên: 07/03/2014, 02:20

... New data on molluscs and their shell microstructures from the Middle Cambrian Gowers Formation, Australia. Palaeontology 53, 97–135. 14 Nakahara H (1991) Nacre formation in bivalve and gastropod ... growing nacre show that each tablet nucleates at a specific loca- tion on the matrix surface [14]. Today, the general con- sensus is that nacre tablets grow from their center and expa...

Ngày tải lên: 22/03/2014, 16:20

... damage, rather than another amino acid, as a result of its greater reactivity with most damaging species, thereby acting as a local antioxidant on the protein surface. Accord- ingly, the damage ... Similar reactions may occur to enable cysteine residues to reduce radicals generated on other aromatic amino acid residues such as phenylalanine and tryptophan [43], and oxidative damag...

Ngày tải lên: 06/03/2014, 09:22

... dIdC was titrated to an optimum, depending on the particular nuclear extract preparation, and that in some assays there was included a monoclonal antibody against dEcR, or a monoclonal antibody against ... immunoprecipitation, the lysate was incubated overnight at 4 °C with rabbit polyclonal antibody against HA (Abcam Ltd). The incubate was then precipita- ted at 4 °C with protein...

Ngày tải lên: 23/03/2014, 13:20

... 5¢-AA G GAT CCA TGC ACA ACG TGG TTT TTG TTC-3¢ (BamHI) and 5¢-AA G GTA CCT TAT TTT TTG TTG GCA GCG TC-3¢ (KpnI) for F40F8.1, 5¢-AA G GAT CCA TGA AAA ACA CTC TGA AAT TGC-3¢ (BamHI) and 5¢-AA G ... 5¢-AA G GTA CCT TAA TGT GGA CGG GAG AAT GG-3¢ (KpnI) for B0001.4, 5¢-AA G GAT CCA TGC ACA ACG TGG TTT TTG TTC-3¢ (BamHI) and 5¢-TTT TCT AGA TCA AAT GCT ATC GTC GCT TCT CG-3¢ (XbaI) for T07C4.1,...

Ngày tải lên: 30/03/2014, 01:20

... of CREB and describe the functions of TORC and salt inducible kinase. Abbreviations AICAR, 5-aminoimidazole-4-carboxamide-riboside; A- loop, activation loop; AMPK, AMP-activated kinase; ATF1, activating ... cAMP-induced CRE activation in COS-7 cells in which kinase domains of SIKs and another AMPK-related kinase, MARK4, completely inhibit the activation [41]. Because AICAR is unabl...

Ngày tải lên: 30/03/2014, 08:20

... support may have advantages over hand-written prescribing (HWP) in terms of standardisation, full audit trail, legibility, use of approved names, specification of key data fields such as route of admin- istration, ... the third case, vancomycin was pre- scribed 1 g intravenously daily to a patient in renal failure, when the appropriate dose would have been to give 1 g and then to repe...

Ngày tải lên: 25/10/2012, 10:39

... dopamine on the aggregation process. Dopamine delayed the lag phase of aggregation marginally to 95.5 h from 86.8 h in the presence of MPTP alone. The apparent rate constant of aggregation in the ... microscopy had confirmed the presence of both amorphous aggregates and fibrillar deposits. Fig. 5. Aggregation of a- synuclein after 240 h. Samples containing MPTP (A and C) and...

Ngày tải lên: 14/02/2014, 19:20