Tài liệu Báo cáo khoa học: "A SNAPSHOT OF KDS A KNOWLEDGE" pot

... atoms) and r j is the standard deviation of B factors. The normalized B factors have a zero mean and unit variance. All atoms that satisfy B z ‡ 4 are treated as outliers and discarded. After ... importin -a nuclear import pathway, provided that CLIC4 can undergo a conforma- tional rearrangement that exposes the NLS in an extended conformation. Database Structural data are available in...

Ngày tải lên: 14/02/2014, 19:20

... 341, 335–351. 3 Lacadena J, A ´ lvarez-Garcı ´ a E, Carreras-Sangra N, Herrero-Gala ´ n E, Alegre-Cebollada J, Garcı ´ a- Ortega L, On ˜ aderra M, Gavilanes JG & Martı ´ nez del Pozo A (2007) Fungal ribotoxins: ... Martı ´ nez-Ruiz A, Garcı ´ a- Ortega L, Kao R, Lacadena J, On ˜ aderra M, Manchen ˜ o JM, Davies J, Martı ´ nez del Pozo A & Gavilanes JG (2001) RNase U2 and al...

Ngày tải lên: 18/02/2014, 08:20

... benzo [a] pyrene-2¢-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases Oksana M. Subach 1 , Diana V. Maltseva 1 , Anant Shastry 2 , Alexander Kolbanovskiy 2 , Saulius Klimas ˇ auskas 3 , ... Wyszynski MW, Gabbara S, Kubareva EA, Romanova EA, Oretskaya TS, Gromova ES, Shabarova ZA & Bhagwat AS (1993) The cysteine conserved among DNA cytosine methylases i...

Ngày tải lên: 19/02/2014, 00:20

... structural data, a general catalytic mechanism was proposed for aminopeptidases that involves an acidic residue acting as a general acid ⁄ gen- eral base and a di-nuclear metal center participating in binding ... BS (1999) Characterization of the enzymatic activity of PSM: comparison with brain NAALADase. Prostate 39, 28–35. 22 Witkin JM, Gasior M, Schad C, Zapata A, Shippenberg T,...

Ngày tải lên: 19/02/2014, 02:20

... that protein family. In addition, we show that both its fold and potential surface partially resemble the structural features of the antimammalian scorpion a- neurotoxins and of the human antibacterial ... distance data by dynamical simulated annealing from a random array of atoms. Circumventing problems associated with folding. FEBS Lett. 239, 129–136. 31. Laskowski, R .A. , Rullman...

Ngày tải lên: 20/02/2014, 11:20

... initial analysis nave been considered, the process which attempts to find causal connections between conceptualizations is activated, in this particular case, the analyzer has already indicated ... CONSUMER of liquids, and a mailbox ts a CONSUMER of mail. Some objects are both SOURCEs and CONSUMERS. A pipe is a CONSUMER of tobacco and a SOURCE of smoke. An Ic...

Ngày tải lên: 21/02/2014, 20:20

... CAGACTAGTGGTTAGAGGAGA GGAATGATGCTGTAGAGACA DENV-1 10482 10661 179 1G4P217 Group 4 ATATGCTGAAACGCGTGAG CATCATGAGACAGAGCGAT DENV-3 104 382 279 1G5P30 Group 5 TTCCAACAAGCAGAACAACAT GCTACAGGCAGCACGGTTT DENV-4 ... CAGACTAGTGGTTAGAGGAGA GGAATGATGCTGTAGAGACA DENV-1 92.1 ± 0.57 73.6 ± 2.31 1G4P217 ATATGCTGAAACGCGTGAG CATCATGAGACAGAGCGAT DENV-3 90.3 ± 1.09 83.9 ± 5.16 1G5P30 TTCCAACAAGCAGAACAACAT GCTA...

Ngày tải lên: 14/02/2014, 19:20

... nrdF + gene was sequenced by a primer walking approach. For DNA analysis, dnastar software (DNAS- TAR Inc., Madison, WI, USA) and clone manager 5.0 (Scientific & Educational Software, Cary, NC, USA) ... GTA GGT TGA TTT CAT GTC GAA TG-3¢; additional XbaI site underlined) and OB 3 (5¢-AAA AGA ATT CTT AGA AGT CCC AGT CAT CGT C-3¢; additional EcoRI site underlined). The amplified PCR fragment...

Ngày tải lên: 15/02/2014, 01:20

... MPH a Forward: 5¢-TAGAATTCGCTGCTCCACAA GTTAGAACT-3¢ Reverse: 5¢-TA GCGGCCGCTTACTTTGGGTTA ACGACGGA-3¢ Mutant MPH b G194P 5¢-CCTGACGATTCTAAACCGTTCTTCAAGGGTGCC-3¢ G198P 5¢-AAAGGTTTCTTCAAG CCGGCCATGGCTTCCCTT-3¢ G194P ... Gribenko AV, Patel MM, Liu J, McCallum SA, Wang C & Makhatadze GI (2009) Rational stabilization of enzymes by computational redesign of surface charge- charge interacti...

Ngày tải lên: 15/02/2014, 01:20

... progressive degeneration of dopaminergic neu- rons of the substantia nigra pars compacta (SNpc) and depletion of striatal dopamine. Dopaminergic neuronal death is accompanied by the appearance of Lewy bodies ... Bossi 2 , Alberto Milli 2 , Elisa Parma 1 , Marzia Bruna Gariboldi 1 , Giovanna Tosi 3 , Leonardo Lopiano 4 and Mauro Fasano 1 1 Department of Structural and Functional Biol...

Ngày tải lên: 15/02/2014, 01:20