Tài liệu Báo cáo khoa học: Steady-state and time-resolved fluorescence studies of conformational changes induced by cyclic AMP and DNA binding to cyclic AMP receptor protein from Escherichia coli ppt
Tài liệu Báo cáo khoa học: Platelet factor 4 disrupts the intracellular signalling cascade induced by vascular endothelial growth factor by both KDR dependent and independent mechanisms ppt
... VEGF 121 -induced proliferation downstream from the receptor. Presumably this inhibition occurs at/or upstream from Raf1 and downstream from PLCc. We found the chemokine receptor CXCR3B, a putative PF-4 receptor [34], in ... arget of the tyrosine kinase activity of the KDR and to be involved in VEGF -induced DNA synthesis [31]. P LCc phosphorylation was induced by...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells docx
... similar characteristics. Effect of chelators on uptake of NTBI The effects of the chelators on NTBI uptake by hepatocytes and Q7 hepatoma cells were marked and similar. All chelators decreased uptake to 20% or less of the ... contrast to NTBI uptake by Q7 cells, the uptake of Tf-bound Fe (TBI) by receptor- mediated endocytosis is much lower in hepatocytes in compariso...
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: A DExD⁄ H box RNA helicase is important for K+ deprivation responses and tolerance in Arabidopsis thaliana docx
... zone (100 lm from the root tip) of Arabidopsis was used to measure the steady flux profile of K + . Table S1. Primers for amplifying the full-length cDNA, promoter and the length of other sequences ... White PJ & Broadley MR (2000) Mechanisms of caesium uptake by plants. New Phytol 147, 241–256. 56 Hampton CR, Bowen HC, Broadley MR, Hammond JP, Mead A, Payne KA, Pritchard J...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf
... hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor Tomio Hashimoto 1 , Minoru Kato 2 , Takeshi Shimomura 2 and Naomi Kitamura 1 1 Department of Biological ... hepatocyte growth factor activator inhibitor type 2; HGF, hepatocyte growth factor; HGFA, hepatocyte growth factor activator; HPAI, highly pathogenic avian influenza; IC 50, the concentra...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... regulatory effects of miR-23a on the expression of IL6R by RT-PCR and western blot, and found an inverse correlation between miR-23a and IL6R expression at both the mRNA and protein levels. To confirm ... downregulation of IL6R by binding to its first conserved binding site, which then leads to the development of gastric adeno- carcinoma. Materials and methods...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus – biochemical characterization and homology modeling doc
... guanosine and guanine, uridine and uracil, cyti- dine and cytosine were 12.2 and 6.2 min, 10.5 and 4.7 min, 15.2 and 6.1 min, 6.8 and 4.2 min and 6.6 and 3.9 min respectively. The amount of purine ... determined by integrating the peak of produced nucleobase and converting this to the amount of nucleobase by means of a standard curve (amount nucleobase versus...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Neuropeptide Y-family receptors Y6and Y7in chicken Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region docx
... regulation of appetite and circadian rhythm, by binding to G -protein coupled receptors. Mammals have five subtypes, named Y 1 ,Y 2 , Y 4 ,Y 5 and Y 6 , and recently Y 7 has been discovered in fish and amphibi- ans. ... in ligand affinity between Y 7 and Y 2 may prove very use- ful for studies of ligand receptor interactions and 3D modeling, and we have previously bee...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf
... transmembrane helix of subunit 8 and helices G and H1 of cytochrome b and between the N-terminus of subunit 8 and helix a of cytochrome b. The figure was constructed from the crystal structure of the yeast ... inner membrane of mitochondria [1,2]. This respiratory enzyme catalyzes the transfer of electrons from ubiquinol to cytochrome c and couples the electron tr...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Phylogenetic relationships in class I of the superfamily of bacterial, fungal, and plant peroxidases pptx
... comparison of four representatives of class I of the superfamily of bacterial, fungal, and plant peroxidases. (A) N-terminal domain and (B) C-terminal domain of catalase–peroxidase from Haloarcula ... presentation of the inferred t ree with the use of an outgroup (manganese peroxidase from Phanerochaete chrysosporium belonging to class II of this superfamily) present...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc
... reader. To determine the kinetic parameters of wild-type and W402F IPU for p anose, mixtures consisting of 4 lgÆmL )1 enzyme and from 43 to 216 m M substrate, and 20 lgÆmL )1 enzyme and 64 to 480 ... isopanose from pullulan, and isomaltose and glucose from panose, and the action patterns of the wild- type and the W402F enzymes were almost identical (Fig. 2)....
Ngày tải lên: 19/02/2014, 16:20