Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit

Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells docx

... FEBS 2003 Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells Anita C. G. Chua 1 , Helen A. Ingram 1 , Kenneth N. Raymond 2 and Erica ... growth and proliferation, is uncertain. Hence, it is of interest to investigate the uptake and metabolism of NTBI in normal and cancer cells, and the e...

Ngày tải lên : 20/02/2014, 11:20

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Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf

... Institute and Hospital and the National Foundation of Cancer Research. All of the tumor types were conﬁrmed by pathologic analysis. The experiments were undertaken with the understanding and written ... on the expression of IL6R by RT-PCR and western blot, and found an inverse correlation between miR-23a and IL6R expression at both the mRNA and protein leve...

Ngày tải lên : 18/02/2014, 04:20

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Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression proﬁling ppt

... AaHNF-4C, lacks the greater part of this A ⁄ B domain and the complete DBD; consequently, it cannot bind DNA [17]. The expression proﬁles of these three AaHNF-4 isoforms differ over the course of the vitellogenic ... development of the most anterior region of the brain [99,100]. Tlx, the verte- brate ortholog of Tll, is required for the correct development o...

Ngày tải lên : 18/02/2014, 13:20

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Tài liệu Báo cáo khoa học: Inorganic phosphate regulates the binding of coﬁlin to actin ﬁlaments pdf

... accelerate the turnover of actin filaments by severing them [3–6], thereby increasing the number of the free pointed and barbed ends, or by increasing monomer dissociation from the pointed end of filaments ... accessible through the closing of the ‘main door’ on the top of the protomer or by some other mechanism. Similarly in G-actin, cofilin decreases the a...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Final steps in the catabolism of nicotine Deamination versus demethylation of c-N-methylaminobutyrate doc

... study and RT-PCR analysis of transcripts. (A) Schematic representation of the pAO1 gene and ORF cluster ﬂanked by Tn554 and DTn. The cluster consists of the pmfR gene, encoding the regulator of the ... expression of these genes depends on the presence of nicotine in the growth medium and we have determined the enzyme activities of the proteins. Our re...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf

... enveloped by subunit 7. The arrows labeled (b) and (c) point to the areas of interaction between the transmembrane helix of subunit 8 and helices G and H1 of cytochrome b and between the N-terminus of ... membrane or lack of detection of the truncated protein by the antibodies. In the W303–1B q° strain the amounts of the other two catalytic subunits...

Ngày tải lên : 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Differentiation stage-dependent preferred uptake of basolateral (systemic) glutamine into Caco-2 cells results in its accumulation in proteins with a role in cell–cell interaction pptx

... FEBS the cells and separated in one dimension by SDS ⁄ PAGE (Fig. 2). MALDI-TOF MS analysis of 36 clearly visible protein bands covering the entire molecular mass range of the 1D gel led to the ... relative uptake of radiolabelled glutamine in Caco-2 cells; (b) by assessing the effect of glutamine on the proteome of Caco-2 cells using a 2D gel electrophoresis...

Ngày tải lên : 20/02/2014, 01:20

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Tài liệu Báo cáo khoa học: Oxygen tension regulates the expression of a group of procollagen hydroxylases docx

... fully support these previous ﬁndings and on the other hand extend them by far and set them in a more general context, as both a-subunits of P4h, PDI as the b-subunit of P4h [13] and the collagen ... up-regulation of the mRNAs of the two P4h a-subunits [aI (P4ha1) and aII (P4ha2)] and of two lysyl- hydroxylases (PLOD1 and PLOD2). These eﬀects of hypoxia we...

Ngày tải lên : 20/02/2014, 02:21

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Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx

... protein inactivation, and receptor sequestration and degradation that together regulate the duration and or the magnitude of the signaling event. In particular, the rapid degradation of signaling proteins by the ... (GRK2), the kinase that regulates the duration of receptor activation, is mediated by the proteasome [7]. Also, it is becoming increasingly cl...

Ngày tải lên : 20/02/2014, 03:20

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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

... switch and alters the expression of the two nuclear genome coded isoforms of CytOX V [10,32]. The regulation of genes CytOX5a and CytOX5b, coding for the two isofoms Va and Vb, parallels that of ... membrane fragments (SMP) by the method of Smith [20], wherein the rate of oxidation of ferrocytochrome cwas measured by following the decrease in absorbency...

Ngày tải lên : 20/02/2014, 23:20

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