Tài liệu Báo cáo khoa học: Structure and membrane interaction of the internal fusion peptide of avian sarcoma leukosis virus pdf

... 2004 Structural study of internal fusion peptide of ASLV (Eur. J. Biochem. 271) 4729 Structure and membrane interaction of the internal fusion peptide of avian sarcoma leukosis virus Shu-Fang Cheng, ... Kantchev and Ding-Kwo Chang Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China The structure and membrane interacti...

Ngày tải lên: 19/02/2014, 16:20

... Hence, the maintenance of a condensed chromatin structure throughout the entire body of a gene may rely on the combined actions of Set3 at the 5¢ end and Set2 at the 3¢ end. In yeast the cycle of ... bp intervals. The lighter colour shades depict the bottom half of the nucleosome, and the exploded view below the octamer depicts the arrangement of the...

Ngày tải lên: 14/02/2014, 18:20

... N-terminal of the mature enzyme and by the ÔflapÕ. The anchorage of the prosegment and of part of the N-terminus in the active site cleft is made by ionic interactions established between Lys11/Tyr13 of ... Like prophytepsin, the precursor form of cyprosin was processed in different isoforms by the excision of the prosegment and of most of the PSI [2...

Ngày tải lên: 19/02/2014, 12:20

... alog (pH ) pK a2 ), Lim1 is the lower limit of the curve, Lim 2 is the middle limit of the curve and Lim 3 is the upper limit of the curve. Stopped-flow kinetic studies of the oxidative half-reaction ... group on Trp57 of the small subunit to a carbonyl group, and (c) insert a second oxygen atom into the TTQ ring [11]. The essential nat- ure of some of th...

Ngày tải lên: 19/02/2014, 07:20

... the positions of the ribose and base of the second nucleotide. In all cases, the base of the second nucleotide interacted with the Asp66–Thr69 loop and with His86 (Fig. 4B). The majority of the ... molecule, the position of the guanine base and most of the phosphate groups of the first nucleotide (Gp) corresponded well with the mononucleotides in...

Ngày tải lên: 18/02/2014, 11:20

... interaction with the phenolate oxygen of Y51, N of G257 and NE2 of Q53 of the symmetry related subunit. Another oxygen atom is held by hydrogen bonding to NE2 of H122 and phenolate oxygen of Y51 of the symmetry related ... formed, the color of the drop had turned yellow, suggesting the conversion of the quinonoid intermedi- ate to other forms of the e...

Ngày tải lên: 18/02/2014, 16:20

... basis for structure- activity studies. The high selectivity of the a-conotoxins, together with the possibility of obtaining detailed information on their three dimen- sional structures and the relative ... so far. The great variability of the conotoxins and their highly specific action on different ion channel subtypes derives from the structure of the peptides w...

Ngày tải lên: 19/02/2014, 12:20

... developments on the theoretical side layed the foundation of the field, such as metabolic control analysis [4,5] and biochemical systems theory [6]. In the 1980s, the development of extreme currents and elementary ... improved over the course of the decade, although it appears that there is a lack of awareness of the fact that a documentation of the computatio...

Ngày tải lên: 14/02/2014, 14:20

... stimulates the production of these miR- NAs and thus represses the expression of their target genes. TGF-b signaling is known to be involved in the epithelial–mesenchymal transition (EMT). The transcription ... activation of the ERK1 ⁄ 2 pathway [20]. Furthermore, the induction of miR-34a depends on the activation of ERK1 ⁄ 2 in K562 cells [21,22]. We have demonstrat...

Ngày tải lên: 14/02/2014, 19:20

... ATP-dependent manner [20]. Next, one strand (the passenger strand) of the miRNA is removed from the RLC, whereas the other strand (the guide strand) remains in the complex to form a mature RNA-induced ... both the BTG4 gene and the miR-34b ⁄ c polycis- toron [28]. Thus, miR-34b ⁄ c expression may be regulated by both the promoter of the host gene and the promoter i...

Ngày tải lên: 14/02/2014, 19:20