Tài liệu Báo cáo khoa học: Endovanilloids Putative endogenous ligands of transient receptor potential vanilloid 1 channels docx

Tài liệu Báo cáo khoa học: Endovanilloids Putative endogenous ligands of transient receptor potential vanilloid 1 channels docx

Tài liệu Báo cáo khoa học: Endovanilloids Putative endogenous ligands of transient receptor potential vanilloid 1 channels docx

... Pharmacol., 14 1, 803– 812 ]. (Received 16 January 2004, revised 13 February 2004, accepted 18 February 2004) Eur. J. Biochem. 2 71, 18 27 18 34 (2004) Ó FEBS 2004 doi :10 .11 11/ j .14 32 -10 33.2004.040 81. x N-arachidonoyldopamine, ... Italy Endovanilloids are defined as endogenous ligands of the transient receptor potential vanilloid type 1 (TRPV1) protein, a nonsel...

Ngày tải lên: 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx

Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx

... kDa 764.39 y6 617 .34 y5 338 .16 b4 290 .17 y2 17 5 .13 y1 211 .16 b2 418 .23 y3 4 51. 25 b5 546. 31 y4 678.35 y 11+ + 877.49 y7 11 92.62 y10 10 77.60 y9 985.52 y17++ 13 55.69 y 11 1426.69 y12 15 39.86 y13 18 14.83 y15 16 99.89 y14 948.55 y8 268 .18 b3 10 49.9 y18++ PLGSDSEGVNCLAYDEAIMAQQDR y6 ... y 21 ++ - 97 16 06.8 b13 - 64 17 22.7 b14 18 51. 0 b15 0 0.5 1. 0 1. 5...

Ngày tải lên: 16/02/2014, 15:20

16 655 0
Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx

Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx

... 2 011 , revised 7 June 2 011 , accepted 16 June 2 011 ) doi :10 .11 11/ j .17 42-4658.2 011 .08 219 .x Proprotein convertase subtilisin ⁄ kexin type 9 (PCSK9) is a secreted protein that regulates the number of ... Low [ 12 5 I]TC-PCSK9 PCSK9-wild type (3) 374 ± 82 2500 ± 400 626 ± 11 3 2800 ± 300 [ 12 5 I]TC-PCSK9 PCSK9-S127R (1) 263 19 00 548 2900 [ 12 5 I]TC-PCSK9 PCSK9-D374Y (1) 68...

Ngày tải lên: 14/02/2014, 14:20

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Tài liệu Báo cáo khoa học: The tandemly repeated domains of a b-propeller phytase act synergistically to increase catalytic efficiency doc

Tài liệu Báo cáo khoa học: The tandemly repeated domains of a b-propeller phytase act synergistically to increase catalytic efficiency doc

... 0.0540 PhyH at 20 °C 2. 81 ± 0.28 11 43 15 .93 17 .76 0. 015 5 PhyH-DII at 35 °C 1. 82 ± 0.23 14 32 5.56 4 .17 0.0029 PhyH-DI -16 8PhyA at 55 °C 14 .78 ± 0.84 19 1 10 .24 12 .28 0.6400 16 8PhyA at 55 °C 13 .02 ± 0.56 240 ... PhyH-DI 12 0 0.523 ± 0. 014 0.448 1. 17 APPA 5 – – 1. 978 ± 0.022 – – APPA 5 PhyH-DI 12 0 2. 310 ± 0.004 1. 982 1. 20 PhyH 12 0 – – 3.260 ± 0 .17 0 – –...

Ngày tải lên: 14/02/2014, 15:20

9 802 0
Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt

Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt

... (A ˚ 2 ) Overall 18 .1 18.3 Protein (chain A, B) 16 .2, 16 .5 16 .4, 16 .3 Ligand 21. 8, 56.0 34.2, 43.2 Solvent 26.5 25.6 rmsd Bond length (A ˚ ) 0.007 0.007 Bond angle (°) 1. 439 1. 113 PDB codes 2xog ... variants at Lys7, Arg10, and Lys66. Biochemistry 37, 12 1 21 12 132. 31 Anderson DG, Hammes GG & Walz FG Jr (19 68) Binding of phosphate ligands to ribonuclease A. Bioc...

Ngày tải lên: 14/02/2014, 22:20

9 627 0
Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc

Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc

... Zeno 51, Pisa, Italy Fax: +39 502 211 450 Tel: +39 502 211 457 E-mail: mtozzi@biologia.unipi.it (Received 19 July 2 010 , revised 10 September 2 010 , accepted 21 September 2 010 ) doi :10 .11 11/ j .17 42-4658.2 010 .078 91. x Cytosolic ... 0 .10 ± 0.02 1. 0 ± 0.2 2.0 ± 0.5 2.0 ± 0.3 0.3 ± 0.06 1. 0 ± 0.3 2.2 ± 0.5 0 .1 ± 0.05 R144E (1) 0 .10 ± 0.05 1. 0 ± 0.2 2.0 ± 1. 0 6.5 ± 1. 0...

Ngày tải lên: 15/02/2014, 01:20

10 563 0
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx

Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx

... DE- 81 filter paper S103 Y 112 R207 /19 9 K173 /16 5 G145/D137 D142 /13 4 E1 41/ 133 L75/67 D2 01/ 193 G77/69 G197 /18 9 G145/D137 A B Fig. 2. Superposition of PRTFDC1 with HPRT-ImmGP (Protein Data Bank code: 1BZY) ... (µmol·min 1 ·mg 1 ) V (µmol·min 1 ·mg 1 ) V (µmol·min 1 ·mg 1 ) 0.2 0 .1 0.0 0 50 10 0 15 0 –50 200 400 600 800 10 00 0 50 10 015 0 200 250 S –50 0 2 4 6 8...

Ngày tải lên: 15/02/2014, 01:20

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Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt

Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt

... detec- tion is 10 pg of protein for assay) [11 ]. COLO 205 SW480 1 10 10 0 10 00 10 000 10 0 000 1 10 10 0 10 00 10 000 10 0000 mRNA copy number mRNA copy number 0 0 10 -fold change 10 -fold change qPCR ... Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST), 1- 1 -1 Umezono, Tsukuba, Ibaraki 305-8568, Japan Fax: + 81 298 8...

Ngày tải lên: 16/02/2014, 08:20

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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx

Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx

... 42.50 17 .50 16 .20 15 .60 16 .40 19 .50 18 .10 17 .60 Mouse T-bet 91. 80 43.90 43.80 17 .20 17 .50 16 .60 15 .60 19 .20 18 .80 16 .80 Zebrafish t-bet 57.00 58.00 91. 00 17 .30 15 .80 16 .70 17 .00 16 .90 17 .20 16 .30 Ginbuna T-bet 57.20 ... FOXP2 ZEBRAFISH FOXP1 ZEBRAFISH FOXP1 XENOPUS FOXP1 XENOPUS FOXP1 CHICKEN FOXP1 CHICKEN FOXP1 RAT FOXP1RAT FOXP1 MOUSE FOXP1 MOUSE...

Ngày tải lên: 16/02/2014, 09:20

20 690 0
Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

... ASF/ SF2-CP ASF/SF2-CP Untreated Arsenite 1 m M DAPI ASF/ SF2ΔRS-CP 0MS2 8MS2 0MS2 8MS2 0MS2 8MS2 12 0 10 0 80 10 0 10 0 0MS2 8MS2 0MS2 8MS2 0MS2 8MS2 10 0 10 0 10 0 10 0 82.94 16 .03 10 0 10 0 10 0. 81 100 10 0 65.4 65.52 9.55 20. 01 * * ** ** ** 6.3 4.6 39 .1 60 40 20 Rluc/Fluc ... contributed equally to this work (Received 10 January 2 010 , revised 10 March 2 010 , ac...

Ngày tải lên: 16/02/2014, 15:20

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