Tài liệu Báo cáo khoa học: The thioredoxin-independent isoform of chloroplastic glyceraldehyde-3-phosphate dehydrogenase is selectively regulated by glutathionylation docx
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... analyses is that the exact binding location is not identified in the experi- ments. Therefore, it is not clear whether the CDE ⁄ CHR is involved in binding these factors. Consistent with a function of ... oncoproteins interfering with the control by E2F and pRB-related pocket proteins. One example of a gene deregulated by viral proteins is Cdc2. The human Cdc2 promo...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc
... involved either in the assembly of the immature HIV-1 capsid, or in the reassembly of CA into a mature capsid. The detailed description of the structure and conformational dynamics of these interfaces, together ... for the architecture of the mature HIV-1 capsid has been proposed that follows the principle of a fullerene cone: the body is composed of curved a...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt
... 2009) doi:10.1111/j.1742-4658.2009.07314.x The mature capsid of human immunodeficiency virus, HIV-1, is formed by the assembly of copies of a capsid protein (CA). The C-terminal domain of CA, CTD, is able to homodimerize and most of the ... for the whole CA has the sequence IPVGEIYKRW, which corresponds to the a-helix 7 of NTD. This region is important for th...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx
... BLP superfamily. The role of the 263 amino acids of the pro-peptide is currently unclear. In order to obtain an insight into the function of the pro-form (proBMP-2), the ability of proBMP-2 to ... phosphorylation. The data presented here suggest that the pro-domain of BMP-2 can alter the signalling properties of the growth factor by modulating the ability...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... understanding of the ACMSD catalytic mechanism is still incomplete. In light of the reported ACMSD upregulation in the liver of streptozotocin-induced diabetic rats and the suppres- sion of such elevation ... elevated level of the pro-inflammatory PA has been proposed to contribute to the development of this frequently fatal clinical manifestations of the disease...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc
... [23], the present results provide only the third demonstration of the accessory function of these proteins. The effect of LlCBP33A on b-chitin degradation is of the same order of magnitude as the effect ... are tolerant to substitutions of either of the discussed amino acids, as long as both are not substituted. Another conspicuous sequence characteristic of Ll...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx
... a dispersion of 0.16 p.p.m. (supplementary Figure S1). The lack of chemical shift dispersion in the HN region as well as in the methyl region (data not shown) is an indicator of the lack of globular ... is an evidence of lack of tertiary structure. On the other hand, NMR spectra suggest that the confor- mation of J1_tmic is at least partially restrained in the...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: The bacterium, nontypeable Haemophilus influenzae, enhances host antiviral response by inducing Toll-like receptor 7 expression ppt
... addition, activation of TLRs is a prerequisite for the triggering of acquired immunity. To date, 11 members of the human TLR family have been identi- fied. Of these, TLR2 is critically involved ... epithelial cell basal medium (Cambrex). The cultures were grown submerged for the first 7 days and then the air ⁄ liquid interface was created by removing medium from the ap...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein Characterization of cold denaturation and urea–protein interactions doc
... (enzyme I of the PTS), the first protein in the cascade of proteins forming the PTS, to HPr, the histidine-phosphocarrier protein. HPr is the smallest protein in the protein cascade of the PTS and it is ... but, on the other hand, the contribution of the backbone should increase as urea concentration is raised as the protein is more disordered. This latt...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx
... recognition of p NPP by the pNPP site at t he rear su rface of the N -domain is due the formation of an hydrogen bond of the NO 2 -group of pNPP with the amino group of N398. The hydrophobicity of the ... F is the normalized fluorescence, [P] is the concen- tration of TNP -ATP, [E] is the concentration of the enzyme, c is the enhancement o...
Ngày tải lên: 19/02/2014, 16:20