Tài liệu Báo cáo khoa học: Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling pptx

... compilation ª 2006 FEBS 4769 Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling Rainer Engers 1 , ... are indeed regulated by Rac signaling. Recently, we have demonstrated that sustained activation of Rac by overexpression of the Rac- specific activator...

Ngày tải lên: 19/02/2014, 05:20

... nucleus. Downregulation of STAT3 expression resulted in reduction of the activation of the hsp70 promoter by Hsp105b. Furthermore, downre- gulation of Hsp105b reduced the expression of Hsp70 in heat-shocked ... bp, and that mutations of this sequence abrogated the activation of the hsp70 promoter by Hsp105b. In addition, overexpression of Hsp105b stimulated the pho...

Ngày tải lên: 18/02/2014, 06:20

... The insoluble fraction of oat spelt xylan was obtained by removing the soluble component from the starting material. First, an extract was made of 1.0 mg xylan per 20 mL of water by shaking the ... linearized pPicZaC-exlA was used to transform P. pastoris strain X33 by electroporation. Extracellular expression of XAN was performed using the EasySelect Pichia expression kit...

Ngày tải lên: 14/02/2014, 19:20

... a sea- sonal pattern of gonadal resting and recrudescence Table 1. Gonadal expression of dmrt1 genes across the fish kingdom. Species Gonadal expression Expression levels Expression localization ... [5]. The prototype members of this group of factors are the Drosophila doublesex (dsx) and Caenor- habditis mab-3 genes. The Dmrt group of molecules is characterized by a conserve...

Ngày tải lên: 14/02/2014, 19:20

... 0.5–5 l g of protein extract was preincubated with 150 lg of heparin in a total volume of 20 lL for 10 min at room temperature in cytoplasmic extraction buffer before the addition of the RNA ... by two plasmin- ogen activators: urokinase-type plasminogen activator in the extracellular environment and tissue- type plas- minogen activator in the circulation. The proteolytic activit...

Ngày tải lên: 16/02/2014, 09:20

... adi- pose tissues were increased in TG mice by the HF diet. mRNA expression of adipogenic genes in WAT of TG mice We measured the amounts of PGD 2 in WAT after 6 weeks of the HF diet. WAT of TG (S55) ... further assess the effect of H-PGDS overexpression on the increase in adipose tissues, the weights of subcutaneous and visceral adipose tissues, as well as of muscle, of...

Ngày tải lên: 16/02/2014, 09:20

... estrogen (E2) modulates the expression of splice variants of the genes encoding ERa, VGEF and Oxytocin [90]. Given the complexity of steroid hormone signaling, multiple modes of action may operate ... in decreased expression of MLL1 target HOX genes without affecting binding of MLL1 complexes to the promoters [14]. Similarly, knockdown of Rbbp5 or Ash2 also reduces the exp...

Ngày tải lên: 16/02/2014, 14:20

... killing, the scavenging of free radicals and the reactivation of degenerated proteins during infection by a family of proteins named ‘thio- redoxins’ is one of the elegant mechanisms of defense and self-sustenance ... the N-terminus of a-2 helix of thioredoxin fold and is separated by a kink from rest of the helix due to presence of a proline [25,48–50]. The kink provide...

Ngày tải lên: 18/02/2014, 12:20

... Brooks SA, Connolly JE & Rigby WF (2004) The role of mRNA turnover in the regulation of tristetraprolin expression: evidence for an extracellular signal-regulated kinase- specific, AU-rich element-dependent, ... lower levels of IL-1b mRNA are due to shortening of the IL-1b transcript half-life, and are not related to the presence of AU-rich elements in the 3¢ UTR. The inter...

Ngày tải lên: 18/02/2014, 14:20

... specific and potent HAD inhibitors. To check for covalent modifications of the enzyme, the effect of the inhibitor on the molecular mass value of HAD was measured; instead of an adduct increase, ... proteomics. Characterization of chloroplast proteins of Arabidopsis thaliana by top-down mass spectrometry. Mol Cell Proteomics 2, 1253–1260. 21 Park JH, Burns K, Kinsland C & Be...

Ngày tải lên: 18/02/2014, 16:20