Tài liệu Báo cáo khoa học: FOXM1c transactivates the human c-mycpromoter directly via the two TATA boxes P1 and P2 docx

... pTATA-WAF- luc, pP1-jun-luc, pP2-jun-luc, pjun -P1- luc, pjun -P2- luc, pP1(junTATA)luc, pP2(junTATA)luc, pP1(WAFTATA) luc, pP2(WAFTATA)luc, pjun(P 1TATA) luc, pjun(P2TA- TA)luc, pWAF(P 1TATA) luc and pWAF(P 2TATA) luc were ... Consequently, these interactions should be important for the new mechanism by which FOXM1c transactivates via the c-myc P1 and P2 TATA boxes. Bin...

Ngày tải lên: 19/02/2014, 05:20

... acid position of the first residue in each motif. (B) Scheme of the AtHELPS gene. Black boxes represent exons and blank boxes represent introns. The position and orientation of the T-DNA insertion ... Characterization and expression analysis of the T-DNA insertion for the helps mutant and OE lines of AtHELPS. (A) The conserved motifs of DExD ⁄ H-box RNA helicases in A...

Ngày tải lên: 14/02/2014, 18:20

... poly G and poly U RNA in vitro [8]. On the other hand, Hume et al. [15] suggested that EWS binds to the proximal-element DNA of the macro- phage-specific promoter of the CSF-1 receptor gene. The ... (lanes 2 and 4) and 32 P-labeled ETS-1 (lanes 3 and 4) or ssDNA L (lanes 1 and 2). (B) EMSA was per- formed with EWS (lanes 2, 4 and 6) and 32 P-labeled Htelo (lanes 3 and...

Ngày tải lên: 15/02/2014, 01:20

... (tfap2a) and also AP-2b (tfap2b) in the development of the facial ectoderm, and for signals from this epithelium that induce skeletogen- esis in NCCs. Zebrafish embryos lacking both tfap2a and ... expres- sion in the face and limbs. In a follow-up study, they found that this conserved cis-acting sequence serves to maintain a level of AP-2a expression that limits the size of th...

Ngày tải lên: 16/02/2014, 09:20

... a hOrn and a haOrn moiety. Furthermore, a long-range 1 H– 13 C correlation was detected between the carbonyl carbon of the serine and the d-CH 2 of the hOrn, which constitutes the DKP. Therefore, ... S3–7. The observed NOE contacts and the long-range 1 H- 13 C correlations verified the structure and are listed in listed in Tables S5 and S6. On the basis of the res...

Ngày tải lên: 16/02/2014, 09:20

... (Fig. 4A). On the other hand, the interaction of low-pH buffer-exposed Z2 antibody was much less dependent on the pH of the buffer. From pH 4.5 upwards, the binding reached a plateau and became ... interferon-c (IFN-c) and other self-antigens Interactions of IVIg with cytokines and other mole- cules of the immune system have been shown to play a role in the immunomodulator...

Ngày tải lên: 16/02/2014, 15:20

... la tien ten XHCN nhu the nao ? Nam 2005, Tdng thd'ng Hugo Chavez tuyen bd ring Venezudla se xay dflng CNXH the ky XXI, khac vdi CNXH the ky XX. Theo ong thi CNXH the ky XXI se da nguyen ... 63 KINH TE THE Gim Ban chdt cua cuoc khung hoang kinh te the gidi, cCfu vdt chu nghTa tu ban hay xay dung chu nghTa xa hoi the ky XXI DAO THE TUAN T 7" ien n...

Ngày tải lên: 17/02/2014, 05:20

Ngày tải lên: 17/02/2014, 05:20

... in their C-termini. Two types of MIM have been identified: MIM1 and MIM2. The former forms an amphipathic helix that binds to the groove between VPS4 MIT domain helices 2 and 3 [29,30], and the ... and pCMV3xFLAG–IST1 as a template. The amplified cDNA fragment was first inserted into the Zero Blunt TOPO PCR Cloning vector (Invitrogen), and the BamHI–EcoRI fragment was the...

Ngày tải lên: 18/02/2014, 04:20

... human IVD. The main chains are represented by ribbons and the atoms of key residues and FAD are shown with a stick model. Helices I and J are coloured gray and the loop between the two helices ... with the neigh- bouring monomer. As shown in Fig. 7B, Tyr377 and Asn379 in the loop region interact with Leu236 and Asp234, respectively, of the neighbouring monomer v...

Ngày tải lên: 18/02/2014, 04:20