Tài liệu Báo cáo khoa học: Octaketide-producing type III polyketide synthase from Hypericum perforatum is expressed in dark glands accumulating hypericins pdf

... Journal compilation ª 2008 FEBS Octaketide-producing type III polyketide synthase from Hypericum perforatum is expressed in dark glands accumulating hypericins Katja Karppinen 1 , Juho Hokkanen 2, *, ... presence of dark glands in the aerial parts of the plant [10–13]. Keywords dark glands; hypericin; octaketide synthase; St. John’s wort (Hypericum p...

Ngày tải lên: 18/02/2014, 18:20

... parameter 1.18 · Z E · Z L is 1.54, from which Z E · Z L % 1.3, suggesting that only a single ionic pair is involved in inhibitor binding. Inhibition of lethal factor protease by aminoglycosides P. Kuzmic ... distinct binding sites, or at the same site but in two different orientations. For neomycin B, the principal binding site (or orientation) is formally characterized by the fr...

Ngày tải lên: 19/02/2014, 06:20

... binding of ACP to the docking site followed by a conformational change in ACP proposed to inject the acyl chain into the sub- strate-binding pocket [32]. If a similar mechanism is involved in ... compilation ª 2006 FEBS Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His -type b-ketoacyl-acyl carrier protein synthases Penny von Wettstein-Knowles 1 , Johan G....

Ngày tải lên: 19/02/2014, 08:20

... comparative in- formation is an important text mining problem and an area of increasing interest. In this paper, we study how to build a Korean comparison mining system. Our work is composed ... applications. Since the comparison mining is an area of increasing interest around the world, our study can contribute greatly to text mining research. In our future work, we have th...

Ngày tải lên: 20/02/2014, 04:20

... P i con- centration, which in turn could affect CYPD binding to F 0 F 1 -ATP synthase, and decreased binding of the inhibitory protein IF 1 to ATPase. IF1 is a naturally occurring protein that inhibits the ... CYPD binding do not translate to changes in ADP–ATP flux rates, even though CYPD binding on the F 0 F 1 -ATP synthase and unbinding by cyclosporin A was demonstrated in the pr...

Ngày tải lên: 14/02/2014, 19:20

... protein kinase; MAPKK, mitogen-activated protein kinase kinase; MBP, myelin basic protein; OXI1, oxidative signal-inducible 1; PDK1, 3-phosphoinositide-dependent kinase 1; PTI1, Pto-interacting ... alone. The kinase-deficient mutant, OXI1 K45R , in which the lysine residue of the ATP bind- ing domain is mutated to arginine, still interacted with PTI1-4. These data indicate that the kinase...

Ngày tải lên: 14/02/2014, 19:20

... and disassembly of cadherin–catenin complexes The cytoplasmic domain of cadherin interacts with F-actin via b-catenin and a-catenin; b-catenin binds to cadherin and a-catenin, which in turn interacts ... b-catenin [25,26], which leads to disassembly of the cadherin–catenin complex. b-Cate- nin is directly tyrosine-phosphorylated by the nonre- ceptor protein tyrosine kinase proline-rich ty...

Ngày tải lên: 16/02/2014, 09:20

... CH 3 -H 4 -folate binding-domain (black barrel) form discrete complexes with the cobalamin-binding domain (dark grey circle). hMS is inactivated approximately every 200–1000 catalytic turnovers [owing to ... (K act of 107 nm) isolated from Pichia pastoris. Our work shows that reactivation of cob(II)alamin MS and incorporation of cobalamin into apo-MS is enhanced through specific protein...

Ngày tải lên: 18/02/2014, 08:20

... decapeptides. In addition to the antisera r-anti-l (made in rat) and gp-anti-dW4 (produced in guinea pig), two antisera discriminating CHH isomers (gp-anti-pQl made in guinea pig and rb-anti- pQd in rabbit) ... test this initial hypothesis, the organization of CHH- and VIH- expressing cells, in relation to iso- mers, was investigated by immunohistochemistry and immunocytochemistry...

Ngày tải lên: 18/02/2014, 11:20

... residue located far from the GTP-binding site, is not involved in contacts with any of the interacting proteins described so far, and is not affected by the 19-residue insertion in Rac1b. There- fore, ... indicating that, in the absence of Lys48, the chain cannot be extended. Con- sistently, inhibition of proteasome using MG132 resulted in an increase of polyubiquitinated Rac1 O...

Ngày tải lên: 18/02/2014, 16:20