Tài liệu Báo cáo khoa học: The antibacterial and antifungal properties of trappin-2 (pre-elafin) do not depend on its protease inhibitory function pptx

... compilation ª 2008 FEBS The antibacterial and antifungal properties of trappin-2 (pre-elafin) do not depend on its protease inhibitory function Ke ´ vin Baranger, Marie-Louise Zani, Jacques Chandenier, ... independent of its antiprotease function. Although we have not deter- mined its exact mechanism of action, we have shown that the antibacteria...

Ngày tải lên: 18/02/2014, 17:20

... fragment ion a t m/z 18 76.56 corresponded to the loss of the nonreducing end C-G-A unit and ammonium from the molecular ion. Further fragmentation gave the fragment ion at m/z 1436.42, owing to the ... signals. The position of C-6 signals of uronic acids was found from HMBC correlations to H-5 protons. Connec- tions between monosaccharides were identified on the basis...

Ngày tải lên: 19/02/2014, 16:20

... account for the promiscuous nature of the synthesis functions performed by the prim–pol domain and to discriminate between the functions of in vitro primase and polymerase. Another finding of our biochemical ... 2008 The Authors Journal compilation ª 2008 FEBS 4391 Zn-binding motif and the two disulfide bonds respec- tively connecting the a4-helix to the b4 strand a...

Ngày tải lên: 18/02/2014, 18:20

... code). The translation product of TAP2iso terminates 14 amino acid residues downstream of the conserved D -loop. The splice variant does not contain the switch region and the b 11 -strand (Fig. ... of the C-terminal truncations and the ability of the exon 12-encoded C-terminal tail to regulate the function of NBD2. Nevertheless, our findings and the phen...

Ngày tải lên: 20/02/2014, 02:21

... However, at concentrations of >5 mUÆmL )1 , the effect of PLC diminished with increas- ing concentrations. At these higher concentrations, PLC strongly antagonized the action of insulin. As ... Tyro- sine phosphorylation of focal adhesion kinase and paxillin reg- ulates the signaling mechanism of the rapid non-genomic action of dexamethasone on acton cytoskeleton. M...

Ngày tải lên: 20/02/2014, 02:21

... isolated and its genomic structure and expression analysis investi- gated. This work will pave the way for further investigation of the biological function of this gene, and the probability of the ... products of b-actin. The x-axis indicates the time-periods of LPS incubation and the relative expression of the carp IL-10 gene on the y-axis. Control...

Ngày tải lên: 20/02/2014, 02:21

... member of the d-subdivision) were unsuccessful or led to the degradation of the isolated species [10]; as a consequence, the stoichiometry of the complex was not established. The formation of stable NrfHA ... hemes. These considerations enabled the revision of a vast amount of existing spectroscopic data on the NrfHA complex that was not originally well inter...

Ngày tải lên: 21/02/2014, 00:20

... Zt % put on this is all my oonbinatioa• and permutation• 2t Z put ton mission•flea on, Z wan two cannibal• on the boat and send them back, then At As Just ridlculou• •t the other end so ... to the report of the task aoClona. ~n the psr~lo,,~ar problem demean of the H~aeionsr£ee and CannLbae8 pusxle, 5he ~aek POliCed ao~Lonl and obJeo~e are defined as o...

Ngày tải lên: 21/02/2014, 20:20

... the CaH-NH fingerprint region of the NOESY spectrum of conomarphin (A) and l-Phe13-conomarphin (B). Fig. S7. Comparison of the three-dimensional struc- tures between conomarphin and l-Phe13-conomar- phin. Table ... mRNA. The original translation products of conotoxin genes are in most cases composed of a sig- nal peptide, a propeptide, and mature conotoxins at the C-t...

Ngày tải lên: 18/02/2014, 17:20

... strong inhibitory effect on human ACMSD. The presence of the metal- locofactor in human ACMSD might also be inferred by our study on the enzyme pH dependence, showing that the increase of the concentrations ... verify incorporation of the desired modification and to ensure the absence of random mutations. The mutagenized plasmids were transformed into P. pastori...

Ngày tải lên: 19/02/2014, 02:20