Tài liệu Báo cáo khoa học: Understanding the binding properties of an unusual metal-binding protein ) a study of bacterial frataxin pdf

... Medical Research Council. Journal compilation ª 2007 FEBS Understanding the binding properties of an unusual metal -binding protein ) a study of bacterial frataxin Chiara Pastore 1 , Marisa Franzese 2 , ... Fe 2+ ⁄ protein ratio, the resonances of Arg20, Asp22 and Asp23 disap- peared, and the resonance of Leu21 shifted. At a 2 : 1 ratio, the resona...

Ngày tải lên: 18/02/2014, 16:20

... semi-structured data made available to search engines, such as relational databases and semantically annotated web documents. Search- ing over such data sources, in many cases, can offer more relevant and ... Evaluation 6.1 Data To evaluate our proposed models and features, we collected queries from three domains, Movie, Job and National Park, and had them manually anno- tated. The annotati...

Ngày tải lên: 20/02/2014, 04:20

... 199 0), (Alterman et al., 199 1) have been and are addressing many complex facets of the problem of mapping Natural Language in- structions onto an agent's behavior. However, an aspect that ... square in half will be asserted in the A- Box and recognized as an instance of ~ - the shaded concept cut (a) square in half - which is a descendant of cut and...

Ngày tải lên: 20/02/2014, 21:20

... 100516804 100517855 XP_003126813.1 XP_003132044.1 Branchiostoma floridae Animals Other animals 1 7233239 XP_002613836.1 Hydra magnipapillata Animals Other animals 1 100198802 XP_002156667.1 Ixodes scapularis Animals Other animals 1 8026286 ... indicates that indepen- dent duplications occurred (a) in a common ancestor of vertebrates, (b) in a common ancestor of land plants, (c) in a...

Ngày tải lên: 14/02/2014, 18:20

... fragments of M-OmpA and I-OmpA displayed a band at a molecular mass of  7 kDa (Fig. 2A, lanes 1 and 2), identified by N-terminal sequencing as frag- ment 264–325 (6.6 kDa). A western blot of a similar gel ... (Beckman SS 34 rotor) at 4 °C. His–OmpA was extracted and purified by Ni 2+ –agarose chromatography as described by the manufacturer (Qiagen, Valencia, CA, USA). Alterna...

Ngày tải lên: 18/02/2014, 04:20

... P450 reductase and the reductase domain of neuronal nitric oxide synthase) to: (a) stimulate formation of holo-MS from aquacob(III)alamin and the apo-form of MS; and (b) reactivate the inert cob(II)alamin ... by apo-MS, a role asso- ciated with the MSR-catalysed reduction of exogenous aquacob(III)alamin to cob(II)alamin [Yamada K, Gravel RA, TorayaT & Matthews RG (200...

Ngày tải lên: 18/02/2014, 08:20

Ngày tải lên: 18/02/2014, 16:20

... HR & Callaghan R (200 8) Resistance to chemo- therapy in cancer: a complex and integrated cellular response. Pharmacology 81, 275–300. 2 Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan ... Thus, ATP and vanadate generate an ADP-vanadate struc- ture mimicking the transition state for the hydrolysis of the c-phosphate of ATP [30]. Figure 5 demon- strates the effect...

Ngày tải lên: 18/02/2014, 18:20

... deleted Plasmids transformed into E. coli BL21(DE 3) Activity against 2MA atdA1 pACYC A2 and pET A3 A 4A5 – atdA2 pACYC A1 and pET A3 A 4A5 + atdA3 pACYC A1 A2 and pET A4 A5 – Control (no deletion) pACYC A1 A2 ... (brown sphere) and the catalytic facial triad of H204, H209 and D356. (D,E) Molecular sur- faces of the substrate channel leading to the binding pocket of t...

Ngày tải lên: 19/02/2014, 02:20

... C in animals and enhance the excretion of l-xylulose in humans with pentosuria and have shown that aminopyrine, metyrapone and other xenobiotics cause an almost instantaneous increase in the conversion ... presence of 10 m M ATP-Mg and in the absence (black bars) or presence (grey bars) of 1m M metyrapone (A) . The effect of the heated high-speed super- natant was further...

Ngày tải lên: 19/02/2014, 07:20