Tài liệu Báo cáo khoa học: Hypoxia downregulates farnesoid X receptor via a hypoxia-inducible factor-independent but p38 mitogen-activated protein kinase-dependent pathway doc

... downregulates FXR via p38 MAPK T. Fujino et al. 1332 FEBS Journal 276 (2009) 1319–1332 ª 2009 The Authors Journal compilation ª 2009 FEBS Hypoxia downregulates farnesoid X receptor via a hypoxia- inducible ... Saitou 1 , Takehisa Atsumi 1 , Takashi Sato 1 , Ken Ando 1 , Shuntaro Hara 2 , Kiyomi Kikugawa 1 and Makio Hayakawa 1 1 School of Pharmacy, Tokyo University of Phar...

Ngày tải lên: 18/02/2014, 13:20

... glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J Neuropathol Exp Neurol 65, 529–539. 25 Takanaga H, Yoshitake T, Hara S, Yamasaki C & Kunimoto ... reverse, 5¢-GACCTTCTTCTCCCGCATCATC-3¢. VEGF: forward, 5¢-ACGAAAGCGCAAGAAATCCC-3¢; and reverse, 5¢- TTAACTCAAGCTGCCTCGCC-3¢. Beta-actin: forward, 5¢-AGGCTCTTTTCCAGCCTTCCT-3¢; and reverse...

Ngày tải lên: 18/02/2014, 13:20

... FEBS naya OA, Kolpakov FA et al. (1998) Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res 26, 362–367. 47 Takahashi S, Takahashi Y, Ito K, Nagano T, Shibahara ... 1162–1168. 13 Nakayama M, Takahashi K, Kitamuro T, Yasumoto K, Katayose D, Shirato K, Fujii-Kuriyama Y & Shiba- hara S (2000) Repression of heme oxygenase-1 by hypoxia in vascular endothelia...

Ngày tải lên: 19/02/2014, 06:20

Ngày tải lên: 16/02/2014, 15:20

... Molecular Probes (Carlsbad, CA, USA). Rabbit pAb against recombinant human calpain 7 and mouse mAb against human calpain 7 were raised as described previously [28]. Peroxidase-conjugated goat anti- (mouse ... 2010) doi:10.1111/j.1742-4658.2010.07822 .x Calpain 7, a mammalian ortholog of yeast Cpl1 ⁄ Rim13 and fungal PalB, is an atypical calpain that lacks a penta-EF-hand domain. Previous...

Ngày tải lên: 18/02/2014, 04:20

... 613 Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X- ray crystallographic analyses Muhammad S. Rohman 1 , Takashi Tadokoro 1 , Clement Angkawidjaja 1 , ... 15458–15463. 29 Kashiwagi T, Jeanteur D, Haruki M, Katayanagi M, Kanaya S & Morikawa K (1996) Proposal of new cata- lytic roles for two invariant residues in Escherichia coli ribonuc...

Ngày tải lên: 18/02/2014, 13:20

... 2009) doi:10.1111/j.1742-4658.2009.07451 .x Hypoxia and hypoxia- related genes are important factors in articular chon- drocytes during cartilage homeostasis and osteoarthritis. We have investi- gated the various apoptotic factors that ... experimentally induced OA Articular cartilage of the femoral condyles from the experimental joints was examined to assess any macro- scopic damage caus...

Ngày tải lên: 18/02/2014, 14:20

... GTT ACT TCC GCA GCT AGG 466–483 Probe amplification for FISH RpCAbrF TAC AAG GAT GCC ATT AGC 613–630 RpCAbrR1 CGT AGC AGT ATC AGC AGT 822–839 RpCAtrFprobe TAC AAA GAT CCA ATC CAG C 616–634 RpCAtrRprobe ... CAA ATG TCC AGT GCC AGT T 757–778 Full-length sequencing of RpCAbr RpCAbrF TAC AAG GAT GCC ATT AGC 613–630 RpCAbrR1 CGT AGC AGT ATC AGC AGT 822–839 RpCAbrR2 AGA GCA GCA GAC CTT ACG 706–723 R...

Ngày tải lên: 18/02/2014, 16:20

... intact protein analyses, and with ongoing advance- ments in protein chromatographic fractionation, ETD can be extended to larger proteins and protein com- plexes. ETD is a powerful dissociation ... Because the experimental and calculated average molecular masses for this protein are in agreement (5382 and 5381 Da, respectively), we conclude that protein L34 in peak I is not post-t...

Ngày tải lên: 18/02/2014, 16:20

... Kuwada M, Teramoto T, Kumagaye KY, Nakajima K, Watanabe T, Kawai T, Kawakami Y, Niidome T, Sawada K, Nishizawa Y et al. (1994) Omega-agatoxin- TK containing D-serine at position 46, but not syn- thetic ... China Sea. Sephadex G-25 was purchased from Amersham Biosciences (Uppsala, Sweden), a ZORBAX 300SB-C18 semipreparative column was from Agilent Tech- nologies (Santa Clara, CA, USA), and...

Ngày tải lên: 18/02/2014, 17:20