... dysfunction. Cell–cell interaction in the neurovascular unit As discussed, all types of cells in the brain have unique roles and coordinate with each other to main- tain brain homeostasis and enable proper ... 2009 FEBS 4635 MINIREVIEW Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovas...
Ngày tải lên: 18/02/2014, 11:20
... VEGF-D, binds and activates this receptor, resulting in the proliferation and migration of lymph ECs and lymphangiogenesis [13]. Angiogenesis in brain diseases Brain stroke Stroke is induced through: ... among tissues in the body, and the risk of edema to brain functions should be carefully considered. Brain edema may increase pressure in the cranial cavity and...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke docx
... MINIREVIEW Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke Ken Arai, Guang Jin, Deepti Navaratna and Eng H. ... whether neurovascular responses after stroke can be reinter- preted in the context of angiogenesis in the brain. Is it possible that some of the acute neurovascular...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx
... coiled-coil domain in the N-termi- nus and a fibrinogen-like domain in the C-terminus. Angiopoietins have a signal sequence in the N-termi- nus for protein secretion, and secreted angiopoietin functions ... University, Japan Introduction A worldwide increase in obesity due to lifestyle changes, such as inactivity and overnutrition, is an increasing medical and social problem i...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx
... Japan Introduction The epidermal growth factor receptor (EGFR) is com- posed of an extracellular ligand-binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. The binding ... carcinomas; IAP, inhibitor of apoptosis protein; JNK, c-Jun NH 2 -terminal kinase; KIP, kinase inhibitor proteins; MEK, MAPK ⁄ ERK kinase; MKK, MAPK kinase; MKP-1, mitogen-activated protein...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry pptx
... therapeutic strategies. Interestingly, Clostridium perfringens entero- toxin is a ligand for CLDN3 and CLDN4 proteins, and binding of the toxin to these claudins leads to rapid cytolysis of cells [26]. Preclinical ... alpha-1 chain, collagen I alpha-2 chain, tubulin beta chain), molecular transducer activity (ITGB2, interferon- induced transmembrane protein 1, integrin alpha-6 and integ...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: How disorder influences order and vice versa – mutual effects in fusion proteins containing an intrinsically disordered and a globular protein docx
... (2008) Mapping alpha-helical induced folding within the intrinsically dis- ordered C-terminal domain of the measles virus nucleo- protein by site-directed spin-labeling EPR spectroscopy. Proteins 73, ... B, Finet S & Longhi S (2005) The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx
... irreversibly inhibit DNMTs [11]. As decitabine contains a deoxyribose group, it is incorpo- rated into DNA [12]. However, because azacitidine contains a ribose group, it is initially incorporated into RNA ... the fibre formed by folding the zig-zagging chain of nucleosomes in inactive chromatin, the location of the linker histone in relation to the nucleosome core particle and linker DNA...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx
... EIIA, B and C domains, with the EIIA and B do- mains being part of the phosphorylation chain and the EIIC domain representing the membrane domain. As all components of the PTS, depending on their ... and mathe- matical models are combined in an attempt to obtain information on the dynamics and regulatory structures of the systems. However, depending on the degree of biological kno...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression profiling ppt
... code for a single protein. Interestingly, during the initial process of identifying the NR family members in the A. aegypti genome, we predicted two isoforms of AaFTZ-F1, differing only in their ... present in its promoter [55]. Further- more, MsHR4 transcripts have been shown to appear only after MsHR3 mRNA and MsHR3 protein decline to low levels both in vivo and in vitro [56...
Ngày tải lên: 18/02/2014, 13:20