Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf

... miR-23a potently promotes the growth of the gastric adeno- carcinoma cell line MGC803, providing the first proof- of- concept that there is a potential link between the tumor promoter miR-23a and gastric adenocarcinoma cell ... MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 rec...

Ngày tải lên: 18/02/2014, 04:20

... and His145Asn mutations on the affinity of metal binding to arginase II To further examine the effects of the His120fiAsn and His145fiAsn mutations on the interaction of the enzyme with manganese ... elec- trostatic repulsion between the a-carboxyl group of the amino acid and the introduced aspartic residue at position 149. On the other hand, as agmatine lacks th...

Ngày tải lên: 20/02/2014, 02:21

... explain the dimerization of the bc 1 complex at this stage (i.e. just after the addition of ISP and Qcr10p). On the other hand, in the transition from the 500 kDa band to the 670 kDa band, a structural ... bc 1 sub-complex, but the presence of only one of these two subunits does not substitute for the other. After the addition of ISP, the binding of the l...

Ngày tải lên: 18/02/2014, 08:20

... the lack of domain B protruding out of the TIM barrel in the place of loop 3 connecting the b3-strand to the a3-helix [9,21]. Sharing domain B by rBATs and GH13 enzymes, and especially the sequence of ... extracellular domain. The segments correspond, in fact, with some of the a-amylase family CSRs, namely the b-strands b2, b3, b4 and b8 of the (b ⁄ a) 8...

Ngày tải lên: 18/02/2014, 13:20

... violet. The dots are stained cells on the bottom of the Matrigel-coated inserts. The number of invasive cells was determined by counting the number of stained cells and then normalizing it to the ... of the mechanisms of this regulation. On the basis of the above findings, our research provides new insights into the role of exon 9 in the regulation of ap...

Ngày tải lên: 18/02/2014, 18:20

... nm; and (b) a wide minimum between 208 and 220 nm. The a-helix and b-strand contents of the protein were calculated with the online programs dichroweb [25] and k2d [26], respectively. With the program ... illustrates the quality of the experimental data (Fig. 2B). Reconstruction of the overall shape of the PLDa2 from the X-ray scattering data was achieved by...

Ngày tải lên: 19/02/2014, 02:20

... decreased the expression levels of HO-2 mRNA and protein in Jurkat T-lymphocytes and YN-1 and K562 erythroid cell lines. To further analyze the effects of hypoxia on the expression of HO-1 and HO-2, ... HO-1 and HO-2 expression in human cell lines We initially analyzed the effects of hypoxia on the expression of HO-1 and HO-2 in human cell lines of bone...

Ngày tải lên: 19/02/2014, 06:20

... distantly related. These are the PDHs and QORs. Finally, there are the two families of ACRs and LTDs, and a few forms that do not belong to any of the families mentioned. Half of the families are ... subclassify the MDR superfamily. Inthe COG database, the human and A. thaliana sequences are presently lacking. Furthermore, COG groups the YADH and CAD families tog...

Ngày tải lên: 21/02/2014, 03:20

... FEBS glycoproteins from the culture media and HCC patient sera. Of these,  60 proteins were discarded, as they were also identified from the sera of HVs. To estimate the abundance of the remaining candidates ... glyco-biomarker candidates by comparison of glycoprotein profiles for further validation. Glycoproteins identified from the sera of HCC patients and culture medi...

Ngày tải lên: 16/02/2014, 08:20

... is the proteolytic component of the toxin, and cleaves six members of the mitogen-activated protein kinase kinase family after being delivered to the cytosol by the cell- binding component of the ... previous work indi- cating the requirement of ERK signaling for survival of these cells, and suggests that different types of cells are killed by LF as a result o...

Ngày tải lên: 16/02/2014, 09:20