Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx

... y3 546.3 y4 617 .3 y5 764.4 y6 877.5 y7 953.5 b16 ++ 10 18. 51 b17 ++ 10 92 .1 b18 ++ 12 55.5 b 21 ++ 13 13 .1 y 21 ++ - 97 16 06.8 b13 - 64 17 22.7 b14 18 51. 0 b15 0 0.5 1. 0 1. 5 4 x10 400 600 800 10 00 12 00 14 00 ... 14 00 16 00 18 00 9 61. 9 b16 ++ 11 91. 1 y10 12 30.6 y20 ++ pY pS 200 400 600 800 10 00 12 00 14 00 16 00 18 00 0 10 0 [M+3H] 3+ 966....

Ngày tải lên: 16/02/2014, 15:20

... mixture of the p21b target with the pPGM1 competitor fragment was treated with cisplatin in the same way, the inten- sity of the R 53 band on the autoradiogram increased with the degree of DNA modification. ... bind- ing to the synthetic target site PGM1 (Fig. 1) . Here, we studied the effects of DNA treatment with cisplatin on p53 (1 363) binding to the p53DB...

Ngày tải lên: 19/02/2014, 05:20

... p160Mybbp1 has been mapped to the Prep1 Hth domain, and specifically to a leucine-rich motif in homology region 1 (hr1) [37]. To test whether Pbx1 or p160Mybbp1 interaction might contribute to the ... 22908, USA Fax: +1 434 924 12 36 Tel: +1 434 243 6752 E-mail: dw2p@virginia.edu (Received 16 December 2009, revised 24 March 2 010 , accepted 30 March 2 010 ) doi :10 .11 11/...

Ngày tải lên: 16/02/2014, 15:20

... Africa Fax: +27 21 808 314 5 Tel: +27 21 808 4507 E-mail: mfessop@sun.ac.za (Received 14 December 2006, revised 14 August 2007, accepted 17 August 2007) doi :10 .11 11/ j .17 42-4658.2007.060 51. x The mechanisms ... respiration (nmolÆmin )1 Æmg )1 protein) 29.4 ± 1. 6 32.6 ± 1. 9 36.6 ± 1. 7* 35.0 ± 2.0 State 3 respiration (nmolÆmin )1 Æmg )1 protein) 14 5.0 ± 9.6 16 5.8...

Ngày tải lên: 18/02/2014, 16:20

... 50S 19 11 1 917 19 11 1 917 U1 911 C – + – + A1 912 U + + ND ND A1 912 C + + ND ND A1 913 G + + + + C1 914 U + + + + C1 914 A + + + + U1 915 C + + + + A1 916 G + + – – A1 916 C + + + + A1 916 U – – – – U1 917 C + – + – A1 918 G ... gene and 17 7 nt from the clpB gene. Preparation of ribosomes and rRNA 23S rRNA variants A1 912 U, A1 912 C, A1 913 G, C1 914 U, A1 916 G, A1 916 C,...

Ngày tải lên: 18/02/2014, 16:20

... However, 17 b-estradiol, a natural ligand of ERs, does not bind to any members of the ERR fam- ily [14 ,19 ]. Likewise, BPA binds only weakly to ERs and does not bind at all to any other receptors of the ERR ... role of Arg 316 in arresting the ligand When the amino acid sequences of the LBD of all the NRs were aligned to that of ERRc, it became notice- ab...

Ngày tải lên: 18/02/2014, 16:20

... (5); Thr 1. 0 (1) ; Ser 4.7 (5); Glu 6.7 (8); Gly 1. 8 (2); Ala 5.6 (6); Val 1. 3 (1) ; Met 2.3 (5); Leu 1. 0 (1) ; Phe 1. 2 (1) ; Lys 8.5 (8), with the theoretical 11 11 T 12 13 14 14 T 15 15 T 16 16 T Identity ... Appli- cation of this trimming treatment to the longest and shortest variants with the wild-type S. castellii sequence (inhibitors 11 and 14 ) and...

Ngày tải lên: 19/02/2014, 00:20

... (L22T11P141R12690, L14T53P137R 016 28, L22T11P138R124 31, and L22T11P137R12300), and the other one encoding an ortholog of HFB1 of T. atroviride (L12T11P 119 R10608). Their sequence relationships and ... HFB1 (P52754; Q17), HFB2 (S626 21; A16), HFB3 (trire.GWV1. 31. 87 .1, scaffold 31: 13 6 622– 13 6 948; A17), HFB4 (estExt_fgenesh1_pg.C_5 011 6, scaffold 5: 390 006–390 493; D25...

Ngày tải lên: 19/02/2014, 02:20

... are: k 1 ¼ 350 ± 40 s )1 and k 2 ¼ 8.4 ± 0.9 s )1 for wild-type cytochrome c; k 1 ¼ 470 ± 60 s )1 and k 2 ¼ 7.4 ± 0.8 s )1 for the K88E ⁄ T89KE mutant; and k 1 ¼ 19 .4 ± 2.3 s )1 for the K13N mutant. ... affinities of the two anions for the protein [11 ,17 ]. We also monitored the effect of sulfate on the perchlorate-induced A-state. As shown in Fig. 6, a...

Ngày tải lên: 19/02/2014, 05:20

... residues 9 10 , 13 16 , 18 – 21, 41, 42, 44 and 61 [15 18 ]. A large database of amino acid sequences is available for the various isoforms of type III AFP. The sequences of at least 12 isoforms (denoted ... estimated to be 0.60 °C for the QAE1 isoform, 0 .11 °C for QAE2, and almost zero for the SP isoforms when the con- centrations of these isoforms was standardi...

Ngày tải lên: 19/02/2014, 16:20