... independently of the presence of AREs (Fig. 6B, lanes 2 and 5). It is possible that in the region located before the AREs, consisting of 343 bp of the 3¢ UTR of the IL-1b transcript, there is a putative ... MCPIP (endogenous and exogenous) starts degradation of IL-1b mRNA and also of its own tran- script. For this reason, the level of mRNA for the wild- typ...
Ngày tải lên: 18/02/2014, 14:20
... the set of case elements that modify the i-th verb in T rs i (T ) : the set of particles in the set of case el- ements that modify the i-th verb in T ns i (T ) : the set of nouns in the set of ... )) the co-occurrence prob- ability of the particle set and the verb, and we call P(n i,j (T )|r i,j (T ), v i (T )) the co-occurrence probability of the cas...
Ngày tải lên: 20/02/2014, 12:20
Tài liệu Báo cáo khoa học: Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase pdf
... 1886–1895 ª 2010 The Authors Journal compilation ª 2010 FEBS 1895 Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase Silva ... that the NarJ chaperone interacts with the N-terminus of the NarG subunit coming from the nitrate reductase complex, NarGHI. I...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc
... is a soft ligand and therefore shows a preference for soft metals. More- over the structures of metallothioneins are not rigid and hence there is little selectivity concerning the size of the ion. ... just the result of the larger ionic radius of Cd(II) over Zn(II) and that the difference in amino acid sequence plays a role. One of the most important aspects is...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase) doc
... of the conserved His and the hydroxyl of the active-site Ser increases the nucleophilicity of the Ser oxygen, facilitating attack of the hydroxy group on the silicon atom of the substrate. This ... transfer to the His residue in the catalytic center. The content of the silicasomes is released into the extracellular space [17], and transported from t...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: A novel c-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 ppt
... A. nicotinovorans is linked to the presence of the megaplasmid, pAO1 [20]. The recent elucidation of the DNA sequence of pAO1 revealed the modular organization of the enzyme genes involved in nicotine ... mutagenesis of the MABO gene The amino acid substitutions in the MABO protein were made with the aid of the Quick Change site-directed mutagenesis kit (Stra...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Mammalian mitotic centromere-associated kinesin (MCAK) A new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents pptx
... functions such as vesicle trans- port, chromosome segregation, and organization of the mitotic spindle. Therefore, one of the other targets of the SQAGs is probably a MCAK. We show here that SQAGs suppress ... binding. The tightness of binding may determine the degree of inhibition. SQAGs inhibit the depolymerization activity of MCAK in vivo To elucidate the MT-dep...
Ngày tải lên: 19/02/2014, 17:20
Tài liệu Báo cáo khoa học: Evidence for interactions between domains of TatA and TatB from mutagenesis of the TatABC subunits of the twin-arginine translocase docx
... domains of TatA and TatB from mutagenesis of the TatABC subunits of the twin-arginine translocase Claire M. L. Barrett and Colin Robinson Department of Biological Sciences, University of Warwick, ... analyzed the effects of substituting groups of basic residues in these regions of TatA and TatB [24]. The present study has increased our understanding of this r...
Ngày tải lên: 19/02/2014, 17:20
Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf
... later than in the case of the histone gene cluster [10]. This difference in the tim- ing of somatic pairing perhaps reflects the difference between the complexities of the regulation of the two systems: ... removal of which shifts the ratio between the strength (indica- ted by the thickness of the curved arrows) of the cis and trans interactions in f...
Ngày tải lên: 20/02/2014, 01:20
Tài liệu Báo cáo khoa học: "Collecting a Why-question corpus for development and evaluation of an automatic QA-system" pdf
... tasks, and up- loads them to the MTurk Web-site. Workers can then browse the tasks and, if they find them profitable and/ or interesting enough, work on them. When the tasks are completed, the employer ... when the task was completed by a worker and returned to the sys- tem. The time between the completion time and the upload time is presumably highly de- pendent on...
Ngày tải lên: 20/02/2014, 09:20