Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

... more in WAT of TG mice than in WAT of WT mice. Serum levels of triglyceride, glucose, leptin and insulin, and insulin sensitivity, in TG mice After 6 weeks of normal or HF diet, serum levels of triglyceride, ... adipogenesis in vivo FEBS Journal 277 (2010) 1410–1419 ª 2010 The Authors Journal compilation ª 2010 FEBS 1419 Pronounced adipogenesis and increas...

Ngày tải lên: 16/02/2014, 09:20

... lines of text and the average comment or page is about 20 lines of text. EIES offers the user a complete set of differing inter- faces including menus, commands, self-defined commands and ... progra,,m4ng of interfaces for individuals and groups. In addition to the standard message, confer- ence and notebook features, EIES has been designed with the incorporation of...

Ngày tải lên: 21/02/2014, 20:20

... affinity and kinetics of binding of PCSK9 to LDLR on HepG2 cells at 4 °C. The extent of [ 125 I]TC-PCSK9 binding increased as cell surface LDLR density increased. Unlabeled wild-type and two gain -of- function ... carried out in single- point binding assays at high initial cell density. Binding-inhibition experiments Cells grown in 12-well plates were washed once with 1 mL of...

Ngày tải lên: 14/02/2014, 14:20

... lesions by EHEC by recruiting a-catenin, a cytoskeletal pro- tein that recognizes actin, to the site of bacterial con- tact [65,66]. In addition, it is also involved in the inhibition of myosin function, ... membrane and increasing Salmonella invasion efficiency [62]. It is of note that both IpaC and SipC are essential for Shigella and Salmonella uptake by macrophages in...

Ngày tải lên: 14/02/2014, 22:20

... seen in the putative T-box DNA-binding domain of t-bet, the STAT protein inter- action domain, STAT protein all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-finger ... is implicated in other protein–protein interactions, a STAT protein DNA-binding domain and an SH2 domain, which binds phosphorylated tyrosine residues in the context of a...

Ngày tải lên: 16/02/2014, 09:20

... attack of the L-hOrn 3 a-amino group onto l-haOrn 4 . Taking into account that the synthetases involved in the bio- synthesis of the DKP-inheriting toxins thaxtomin and fumitremorgin also contain ... (solvent B) at a flow rate of 0.3 mLÆmin )1 : lin- ear increase from 0% B to 50% within 20 min followed by a linear increase to 95% B in 5 min, holding B for an additional 5 min. Thi...

Ngày tải lên: 16/02/2014, 09:20

... uncoupling in hepatocytes leads to PTP opening and cell swelling, an event that is probably reduced in extent by CsA. CsA specifically inhibits PTP opening by binding to cyclophilin D in the matrix and ... swelling of liver and heart mitochondria by cyclosporine is probably caused by the inhibitor binding to mitochondrial-matrix pept- idyl-prolyl cis–trans isomerase an...

Ngày tải lên: 16/02/2014, 09:20

... ⁄ ) Increased Increased Increased NPY levels 65 NPY ) ⁄ ) NPY Increased TVB and CBV Increased Normal ND 66 TTR ) ⁄ ) Transthyretin Increased bone mineral density and TBV Increased Normal Increased ... leptin levels 45,51 Y2 ) ⁄ ) ob ) ⁄ ) Leptin and Y2 Decreased TBV and CBV in relation to Y2 ) ⁄ ) Increased Increased Increased NPY levels 45,61 Y1 ) ⁄ ) Y1 Increase...

Ngày tải lên: 18/02/2014, 04:20

... limitation is retreating, whereas the importance of accurate modeling and analy- sis approaches aiming at understanding the complex interactions in living cells is increasing. Materials and methods The ... at any point x in the domain, either by explicitly solving Eqn (15) (with m ¼ 1) at that point in the way described above or, instead, by first tabulating g 1 over a fine grid...

Ngày tải lên: 18/02/2014, 06:20

... proteins use their BTB ⁄ POZ domain to interact with the cullins CUL3A and CUL3B [3,4,16], we inves- tigated what kind of protein–protein interactions were facilitated by their MATH domains by ... with CUL3 and other BTB proteins [2,16], it remains unclear what kind of interactions are mediated by the MATH domain in plants. In this article, we show that the MATH domain of...

Ngày tải lên: 18/02/2014, 06:20