Tài liệu Báo cáo khoa học: Applications and trends in system

Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx

... protein kinase; MCF, macrophare chemotactic factor; MCIP, modulatory calcineurin-interact- ing protein; MDCK, Madin Darby canine kidney; MEF, mouse embryonic ﬁbroblast; MEK, MAP kinase/ERK kinase; ... compilation ª 2011 FEBS 2785 REVIEW ARTICLE Applications and trends in systems biology in biochemistry Katrin Hu ¨ bner, Sven Sahle and Ursula Kummer Department of Modeling of...

Ngày tải lên : 14/02/2014, 14:20

91
733
0

Tài liệu Báo cáo khoa học: "DESIGN AND IMPLEMENTATION OF A LLXICAL DATA BASE " docx

... viewpoint. INTRODUCTION It has been traditionally assumed by computational linguists and particularly by designers of large natural language processing systems such as machine translation systems ... will be pointed out below. In contrast with the common use in computational linguistics, 9in this model morphology is essentially static . By interpreting morphology as relatio...

Ngày tải lên : 22/02/2014, 09:20

8
535
0

Tài liệu Báo cáo khoa học: Applications of diagonal chromatography for proteomewide characterization of protein modiﬁcations and activity-based analyses doc

... that binds proteins in their nucleotide-binding region and then covalently modifies nucleophilic amino acids (especially tyrosine and lysine) in its proximity [75]. In the past, FSBA was mainly ... character- ize ATP-binding and GTP-binding proteins in cells, we profiled purine-binding proteins on a proteome scale [40]. For this purpose, we used 5¢- p-fluoro- sulfonylbenzoyladenosi...

Ngày tải lên : 18/02/2014, 16:20

13
578
0

Tài liệu Báo cáo khoa học: "Applications of GPC Rules and Character Structures in Games for Learning Chinese Characters" doc

... hints to link the meanings and writings of Chinese characters. For instance, “河”(he2, river) [Note: Chinese characters will be followed by their pronunciations, denoted in Hanyu pinyin, and, ... ‡↑↕ Academia Sinica, Taiwan † chaolin@nccu.edu.tw, ‡ chiaying@gate.sinica.edu.tw Abstract We demonstrate applications of psycholin- guistic and sublexical information for learn- in...

Ngày tải lên : 19/02/2014, 19:20

6
590
0

Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

... proteins containing methyl binding domains (MBDs) which assem- ble complexes containing repressive HMT and DNMT proteins that act in a concerted fashion to maintain both DNA methylation and H3-K9 ... modiﬁcation and are maintained in a constitutively active state by CXXC domain proteins that bind to non-methylated CG sequences. These proteins include MLL1 and the CG-binding prot...

Ngày tải lên : 14/02/2014, 18:20

29
743
0

Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx

... repressing the indicated targets and presumably hundreds of other as yet unidentiﬁed targets. (B) miR-34a and the miR-34a-binding site in the 3¢ UTR of genes shown in (A). miRNAs and cell signaling ... miR-17- 5p and miR-20a are induced in a manner that depends on cyclin D1 and repress the expression of cyclin D1. Hence, miR-17-5p ⁄ 20a and cyclin D1 form a feedback loop an...

Ngày tải lên : 14/02/2014, 19:20

9
684
0

Tài liệu Báo cáo khoa học: MicroRNAs and epigenetics doc

... numbers in the ‘binding sites’ column represent the distance (bp) between the stop codon and binding sites of seed sequences in the miRNAs. The letters ‘c’ and ‘p’ with respect to miRNA binding site ... melanoma and acute lymphoblastic leukemia [31–34]. In breast cancer, the miR-9-1 locus is highly methylated not only in invasive ductal carcinoma, but also in ductal carci- nom...

Ngày tải lên : 14/02/2014, 19:20

12
636
0

Tài liệu Báo cáo khoa học: MicroRNAs and cardiovascular diseases ppt

... Targets Gene symbol Function Binding site in mouse Conservation in mouse Binding sites in human Conservation in human SNPs (dbSNP) References Cardiac development miR-1 Hand2 HAND2 Decrease in cardiomyocyte proliferation Position ... in metabolic syndrome is caused by the insulin- induced increase in SREBP1c mRNA and protein levels [119,120]. Low HDL often accompanies this situ...

Ngày tải lên : 14/02/2014, 19:20

15
684
0

Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt

... similarity in the K m values is attributable to the uracil moiety binding in the same fashion [38], which could trigger the initial binding of both substrates. In UpG, the binding of the guanine moiety ... and has numerous interesting homologs [2–4]. In humans, angiogenin (RNase 5) is an inducer of neovascularization, and plays an important role in tumor growth [5]. Eosinophil-d...

Ngày tải lên : 14/02/2014, 22:20

9
626
0

Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc

... sites 1 and 2 and involved in binding of adenylic nucleotides and BPG. Our results partially conﬁrm the molecular model- ling, suggesting that effector site 1 is the binding site for Ap 4 A and ... S2), and, in particular, a modiﬁcation in the interaction of this resi- due with Asp351 (directly involved in Mg 2+ binding) and His352 both belonging to motif III. Remarkably,...

Ngày tải lên : 15/02/2014, 01:20

10
563
0