whats at the other side of a black hole
Báo cáo khoa học: Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a hemeregulated phosphodiesterase from Escherichia coli pptx
... DosH as a template and using the following respective 5Â-sense primers: 5Â-gatga gtcgggagACCcagctggagaaaaaag-3Â,5Â-gatgagtcgggagTTTcag ctggagaaaaaag-3Â,5Â-ggacccgttttgcgACCtcgaaagtgagc-3Â, and ... decreased the rate of auto-oxidation [5], whereas Ala and Asn substitutions at Asp40, an amino-acid residue that interacts via two water mole- cules with the proximal ligand His77, markedly increased ... mutations, although the effects of the Leu99 and Leu115 muta- tions were modest compared with those of Met95 mutations. It seems likely that potential data based on our data and that of others have accuracies of...
Ngày tải lên: 16/03/2014, 13:20
Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx
... the catalytic activities in the reductive acetylationassaymeasuredwiththefreelipoyldomainas substrate (Table 1) and that the PDH complex activity was measured with pyruvate at a concentration of ... assays, the E1aS283C and E1aF26 6A mutants behaved essentially the same as wild-type E1. In the DCPIP assay, the E1aY28 1A and E1aR28 2A mutants displayed a catalytic activity about twice that of ... (Fig. 3). The reaction mixture with E1 was incubated for exactly 10 min at the relevant temperature and the catalytic activity at that temperature was then determined. The inactivation temperatures...
Ngày tải lên: 20/02/2014, 23:20
Tài liệu The Proof is in the Pudding - A Look at the Changing Nature of Mathematical Proof doc
... will ever find a counterexample, nor ever gainsay that particular mathematical fact. It should not be thought that the generation of mathematical proofs is mechanical. Far from it. A mathematician discovers ... solidity of mathematics (see also Section 0.9). But mathematics is applied in a variety of ways, in a vast panorama of disciplines. And the applications are many and varied. Other disciplines often ... clear that mathematicians will have difficulty escaping from the Kan- tian fold. Even a Platonist must concede that mathematics is only accessible through the human mind, and thus all mathematics...
Ngày tải lên: 21/02/2014, 09:20
Báo cáo khoa học: Do N-terminal nucleophile hydrolases indeed have a single amino acid catalytic center? Supporting amino acid residues at the active site of penicillin G acylase pptx
... investi- gation of Perakyla et al. on the catalytic reaction of AGA, however, predicts that, energetically, the highest point in the acylation step is the nucleophilic attack on the carbonyl carbon of ... deriva- tive. These structures are mimics of the stationary points along the reaction pathway; they depict the changes in the spatial structure of the active site during catalysis. Phenylacetic acid ... titration of active site. Bioorg Khim 3, 547–553. 25 Yamagami C, Takao N, Tanaka M, Horisaka K, Asada S & Fujita T (1984) A quantitative structure–activity study of anticonvulsant phenylacetanilides....
Ngày tải lên: 16/03/2014, 01:20
THE CHEMICAL HISTORY OF A CANDLE A COURSE OF LECTURES DELIVERED BEFORE A JUVENILE AUDIENCE AT THE ROYAL INSTITUTION ppt
Ngày tải lên: 22/03/2014, 14:20
Breast Cancer In Younger Women - Proceedings Of A Conference Held At The National Institutes Of Health, Bethesda, Maryland, January 28, 1993 pot
Ngày tải lên: 28/03/2014, 23:20
A Rogue Economist Explores the Hidden Side of Everything ppt
Ngày tải lên: 29/06/2014, 12:20
economics - freakonomics - a rogue economist explores the hidden side of everything - s d levitt & s j d~0
Ngày tải lên: 04/11/2014, 15:40
Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"
... expression of Cx40 and Cx43 were elevated in the neointimal area at the early stage of atherosclerosis. The mRNA and protein expression of Cx43 were significantly down-regulated by losartan treatment ... losartan group (panel C). In panel A, the elastic lamina was clear and intact; endothelia and smooth muscle cells (arrow) arranged regularly. In panel B, the elastic lamina was incomplete and ... Abstract Aim: to investigate effects of Losartan on expression of connexin 40 and 43 (Cx40 and Cx43), in arteries at the early stage of atherosclerosis in a rabbit model. Methods: A total of...
Ngày tải lên: 26/10/2012, 09:39
The Marketing Strategy of a multinational join stock company.doc
... distribution of ideas, goods, and services to create exchanges that satisfy individual and organizational goals” 2 . The writer of the book The Silk Road to International Marketing” had another ... The Marketing Strategy of a multinational join stock company multinational join stock company has a certain advantage: a multinational join stock company has always kept its prices as competitive ... without any product changing. Although it retains the scale economics on the manufacturing side the firm sacrifices potential saving on the communication way . another strategy is dual adaptation....
Ngày tải lên: 27/10/2012, 16:51
INTRODUCTION - The Hidden Side of Everything
... real-estate agents—use their infor- mational advantage to serve their own agenda. However, they can be beat at their own game. And in the face of the Internet, their informa- tional advantage ... control or a strong economy or new police strategies that finally blunted the American crime wave. It was, among other factors, the reality that the pool of potential criminals had dramati- cally ... himself. That is, Candidate A today is likely to be similar to Candidate A two or four years hence. The same could be said for Candidate B. If only Candidate A ran against Candidate B in two consecutive...
Ngày tải lên: 17/10/2013, 18:20
Meeting the Business Side of Google
... is a search engine dedicated to displaying printed catalogs and linking to their sites. It’s available only to companies that publish such catalogs. Froogle is available to any business that ... largest publishers, manufacturers, and e-tailers. As with eBay, small and large participants enjoy the same benefits. The Three Goals of Every Webmaster Innumerable business plans operate side ... (participants controlled their costs and tracked their returns). In time, the advantages of eBay’s system got the attention of midsize brick-and-mortar stores, which now operate eBay outlets as...
Ngày tải lên: 24/10/2013, 08:20
LECTURE SLIDES ON NONLINEAR PROGRAMMING BASED ON LECTURES GIVEN AT THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MASS DIMITRI P. BERTSEKAS
... Duality ã Organization COMPUTATION PROBLEM ã Iterative descent ã Approximation ã Role of convergence analysis ã Role of rate of convergence analysis ã Using an existing package to solve a nonlinear programming ... Sensitivity Duality ã Computation by iterative algorithms Iterative descent − Approximation methods − Dual and primal-dual methods LOCAL AND GLOBAL MINIMA f(x) x Strict Local Minimum Local Minima Strict ... x k , the method ob- tains x k+1 as the minimum of a quadratic approxima- tion of f based on a sec- ond order Taylor expansion around x k . CONVERGENCE RATE OF PURE FORM ã Consider solution of...
Ngày tải lên: 26/10/2013, 17:15
Tài liệu Issues Involved When Updating the Primary Key of a Parent Row pptx
... in the child DataTable. This is the default. None Indicates that no action takes place. SetDefault Indicates that the DataColumn values in the child DataTable are to be set to the value in the ... stored in a DataTable named ordersDT. ã The customersDT and ordersDT DataTable objects are related to each other using the following DataRelation: ã DataRelation customersOrdersDataRel = ã ... you change the DataColumn in the parent DataTable on which the ForeignKeyConstraint was created, then the same change is also made in any corresponding DataRow objects in the child DataTable....
Ngày tải lên: 24/12/2013, 01:17