what we know and do not know

... decrements and the numerous interactions between different downstream outcomes For example, how rapidly we lose lean muscle mass when sick and ‘cytokine-emic’ in the ICU? How effectively we replete ... HL69991 and R01 HS/HL11620), AHRQ (R01 HS/HL11620), and NIGMS (R01 GM61992) to determine intermediate and long-term outcomes of critical illness References So how we tease this out? Fundamentally, we ... How often does loss of lean muscle mass impair critical physical functions, such as getting in and out of bed or a chair? How often, and in whom, does change in physical capability domino into...

Ngày tải lên: 12/08/2014, 20:20

... self-interest not only frequently distorts what we see when we look at other animals, it also in important ways determines what we not see, what we are blind to This book is about seeing what animals ... nor know What stranger’s feet may find the meadow And trespass there and go, Nor ask amid the dews of morning If they are mine or no Nature, as he says, is witless It is not kind, not cruel, not ... Beyond that, however, lies a deeper and perhaps more serious problem: the risk that if we claim our kinship too insistently we will not see what the animals actually do, because we will see only...

Ngày tải lên: 01/06/2014, 10:54

... other hand, responded to CCL3 via CCR1, as these cells did not express CCR5, and were not affected by blockade of CCR5 Although blocking antibodies to CCR1 are not commercially available, we would ... regulation of monocyte and alveolar macrophage recruitment in response to the chemokines CCL2 and CCL3 We report that freshly isolated alveolar macrophages did not express CCR2, and were unresponsive ... the membrane and to the other side, but before detachment and falling into solution on the opposite side of the membrane At least five fields were counted per well and 15 total fields were counted...

Ngày tải lên: 11/08/2014, 08:21

... the future and progress is being made in identifying conserved amino acid sequences associated with past pandemics [5] but we don’t yet know enough about what determines infectivity and virulence ... induced by viral infection and in turn induces cellular anti-viral proteins that interfere with viral replication; and we have already mentioned the HA and the NA, and members of the viral polymerase ... conserved pocket in the HA stem region [8] Analogous mAbs have been found for HIV What we don’t yet know, however, is how to make a vaccine that induces the human immune system to make these...

Ngày tải lên: 06/08/2014, 19:20

... meta-analyses of randomised trials, because many of the data in those came from trials with higher than licensed doses of coxibs, and maximum daily doses of NSAIDs This does not reflect clinical ... adverse events they were overestimated by at least 400-fold The way in which we perceive and process numbers seems to be very different from how we perceive and process words, and different in different ... observational and other studies of NSAIDs there were large differences between drugs [6] Similarly, differences between individual coxibs are apparent for gastrointestinal bleeding [7], and between individual...

Ngày tải lên: 09/08/2014, 10:23

... who did not distinguish between term and preterm children, included children up to three weeks of age, and did not consider the mode of presentation Correlations between palatal width and size ... frenulum to a connecting line between the tubera) width and length with bodyweight and total body length in 100 male newborns were shown to be of low order (between 0.37 and 0.56), as the palatal dimensions ... palatal and alveolar cysts, Donley and Nelson [59] did not find significant differences between a cohort of caucasian children and a group of non-caucasian infants established from black, Latino and...

Ngày tải lên: 11/08/2014, 23:22

... infant, [BW] birthweight, [LBW] low birthweight, [NBW] normal birthweight, [VLBW] very low birthweight, [NBW] normal birthweight, [GA] gestational age, [GW] gestational weeks, [NS] not significant ... PT/LBW and term infants' palatal measurements Results and Discussion Seventy-eight articles published between 1940 and 2000 were included in the analysis of descriptions of the palatal morphology and ... bezogene Wanderung der Seitenzähne, seine Expansion bei Anwendung zweier verschiedener orthodontischer Behandlungsmethoden Fortschr Kieferorthop 1966, 27:121-140 Ashley-Montagu MF: The form and dimension...

Ngày tải lên: 11/08/2014, 23:22

... Critical Care Vol 13 No Zygun However, the small sample size and non-randomized methodology limit the generalizability of these results Importantly, alternatives ... these limited data are insufficient to mandate changes to standards of care, they provide ethical justification for the examination of these standards in randomized controlled trials Ultimately, ... Maggiore and colleagues emphasize the need for prospective randomized controlled studies in the neurotrauma population It is clear that our interventions have potential both for benefit and for...

Ngày tải lên: 13/08/2014, 18:22

... GE, and TW designed the study; SF, GE, and PKH reviewed the literature; SF and GE collected and analyzed the data; and SF, GF, PKH, and TW wrote the manuscript All of the authors revised and ... implementing LTP, and more knowledge on their harms and benefits are required We believe that considering the options and all the risks and benefits LTP is a proper way of handling these patients, ... laerdalfoundation.org/studier_hypoteser.html] doi:10.1186/1757-7241-19-45 Cite this article as: Fattah et al.: The lateral trauma position: What we know about it and how we use it? A cross-sectional survey of all Norwegian emergency...

Ngày tải lên: 13/08/2014, 23:20

... (DSS) And while that is true, it is perhaps also too facile As they note, their system does not offer DSS-type warnings about drug-drug interactions, allergies, or toxic doses; however, it does ... count errors that not affect patients We almost always count potential errors, not actual adverse drug events; and even then, we usually find the inconsequential errors When Berger and Kichak [3] ... possible/potential errors If we examine patients’ charts, we may see both prevented and administered errors (There are undoubtedly other, undetected errors.) Berger and Kichak [3] make the critical...

Ngày tải lên: 25/10/2012, 10:39

... individuals of the same species, between phylogenetically-related species (but not between individuals of the same species) or between ecosystems (but not between species within the same ecosystem) ... Carabids and butterflies but not moths [71] Temperate herbaceous plants [15] Temperate grassland herbs [14, 25, 72] Temperate and Mediterranean grassland herbs [15, 66, 72] Temperate butterflies but not ... (e.g tree species selection) and management (e.g retention of deadwood) Acknowledgements: We would like to thank Christophe Bouget, Mike D Morecroft and G Landmann and one referee for their constructive...

Ngày tải lên: 07/08/2014, 16:20

... V10 Gy and mean lung dose even stronger correlations were found between planned and recalculated values (Table 3) The recalculated V10 Gy was about 8% higher for the UD plans, and 8% lower for ... the dose received by 95% (D95) and 99% (D99) of the PTV, and the isocenter dose Conformality of the PTV coverage was evaluated by the ratio of the volume of the prescription isodose (60 Gy) and ... values (R2 = 0.99 and 0.96 for UD and EPL plans, respectively) 50% planned UD and EPL values, respectively (Table 2) For the mean lung dose, the UD and EPL plans both achieved a 13% lower value compared...

Ngày tải lên: 09/08/2014, 09:22

... conditions and under local infiltration of anaesthesia There are clear post study protocols for weightbearing and medical support Results and discussion What have we learnt about foot and ankle ... function in terms of the entire foot, and, given what we know about the variation between subjects, the general ranges of motion likely at specific joints, and what is observable clinically, rationalise ... degrees of freedom as the human body Loads must be applied to the specimen and its tendons at a magnitude and rate as occurs in gait (or as close as possible) Moving the specimen and loading the...

Ngày tải lên: 10/08/2014, 21:23

... iron and transferrin saturation were all normal Ultrasound abdomen and MRCP were normal Liver biopsy showed evidence of interphase hepatitis stage 3/6, with focal intrabiliary steatosis and mild ... prednisolone and azathioprine The serum ALT and AST were maintained at the 3-4 times above the normal, but the ALP and bilirubun progressively increased (Figure 1); so prednisolone and azathioprine were ... examination of the abdomen showed hepatosplenomegaly and moderate amount of ascites The echocardiogram was normal Upper gastrointestinal endoscopy showed grad III esophageal varices Endoscopic examination...

Ngày tải lên: 13/08/2014, 13:20

... purely musculoskeletal Wenban also described the frequency of visits, after a 12 weeks intensive care period, as times per week for weeks, time per week for weeks, and time per weeks for the reminder ... search terms were "chiropractic", "maintenance care", and "prevention", both as Mesh-term and free text However, fewer articles than those already known by the authors appeared, and therefore ... examination method is objective and valid and those who depend (also) on http://www.chiroandosteo.com/content/16/1/3 patients' signs and symptoms for their diagnosis and treatment Nevertheless, maintenance...

Ngày tải lên: 13/08/2014, 14:20

... Australia, Canada, and the United Kingdom (e.g see Fearnley and Beattie) What we know about audit quality? Summing up, it turns out that we know more about audit quality than we might have originally ... firms were Arthur Andersen, Arthur Young, Coopers and Lybrand, Deloitte Haskins and Sells, Ernst and Whinney, KPMG, Price Waterhouse, and Touche Ross The Big came into being in 1989 when Ernst and ... studies have examined endogeneity and these studies are generally supportive of the research results cited above See Hogan (1997), Ireland and Lennox (2002), and Weber and Willenborg (2003) Moving...

Ngày tải lên: 06/01/2015, 19:42

... York RANDOM HOUSE and colophon are registered trademarks of Random House, Inc Library of Congress CataloginginPublication Data Duhigg, Charles The power of habit : why we what we in life and business ... has expanded in ways we couldn’t have imagined fifty years ago We now know why habits emerge, how they change, and the science behind their mechanics We know how to break them into parts and rebuild ... STARBUCKS AND THE HABIT OF SUCCESS When Willpower Becomes Automatic THE POWER OF A CRISIS How Leaders Create Habits Through Accident and Design HOW TARGET KNOWS WHAT YOU WANT BEFORE YOU DO When...

Ngày tải lên: 11/03/2014, 18:09

... Bobby and Tess are busy, and probably could not tell you what was happening in the latest reality TV 11 Www.wowebook.com GET A LIFE, NOT A JOB show, but they are also highly fulfilled doing what ... line and will be emotionally satisfying, putting you back in control of your career and your future Fear of change and the unknown—“I wouldn’t know what to if I left this job This is what I know ... life will involve another element—knowing yourself, your needs, and your motivations well enough to understand how you like to work and what engages you in your work 39 Www.wowebook.com ...

Ngày tải lên: 16/03/2014, 21:45

... Andrews would tell us), but what we often need is a manual that knows what we already understand and just tells us what' s different and what' s the same That's what this book is all about We know ... necessarily perfectly In Appendixes A and B ,we explain what does and doesn't translate and how you should best use this feature Our colleague Sandee Cohen notes that people who start using InDesign ... gathering what you need when you need it Note that we have no intention of having 'this book cover everything you ever wanted to know about InDesign Sure, we cover a lot of ground, and we take...

Ngày tải lên: 01/06/2014, 09:48

... số nhiều: LET US NOT + V hay LET’S NOT + V Ngôi số hay số nhiều: Dùng DO NOT + V (bare infinitive) hay DON’T + V (bare infinitive) please để diễn tả lịch Let’s not tell him about that (Chúng ta ... từ thứ hai lại dùng thể phủ định, ta không dùng donot để viết mà dùng not to Câu viết tiếng Anh sau: I want you not to forget that Unit 20 Date and time (Ngày tháng thời gian) Date Date ngày ... shut the door, please? (Anh làm ơn đóng dùm cánh cửa không?) Will you please be quiet? I’m studying.(Anh có vui lòng im lặng không? Tôi học.) What shall I do? (Tôi làm đây?) Where shall we go this...

Ngày tải lên: 19/06/2014, 18:20