... of native tissue macrophages have not been done Comparable to CCL2, CCL3 is another member of the CC chemokine family and has chemotactic activity for monocytes and macrophages [21] Although CCL3 ... basophils and activated T lymphocytes, and can also bind CCL5 (RANTES) and the monocyte chemotactic proteins CCL8 (MCP-2) and CCL7 (MCP-3) [30] CCR1 is rapidly internalized after exposure to its ligand(s) ... monocytes, on the other hand, responded to CCL3 via CCR1, as these cells did not express CCR5, and were not affected by blockade of CCR5 Although blocking antibodies to CCR1 are not commercially available,...
Ngày tải lên: 11/08/2014, 08:21
... Both trappin-2 and trappin-2 A62D ⁄ M63L had dosedependent fungicidal activity against both swollen A fumigatus conidia and C albicans pseudoconidia but were not active against dormant (i.e metabolically ... manner, except for K pneumoniae and H influenzae, which were less sensitive at high doses than at low doses of approximately lm (Figs and 3) The minimum effective dose S aureus ATCC 25923 P aeruginosa ... Aspergillus fumigatus and Candida albicans, in addition to its antibacterial properties [13] This has been attributed to its N-terminal domain and is comparable to that of human defensins and human lysozyme...
Ngày tải lên: 18/02/2014, 17:20
DO NOT DELAY: BREAST CANCER AND TIME, 1900-1970 pdf
... among these beliefs and values and the routines of women, doctors, researchers, public health activists, and other actors in this struggle to make sense of, and respond to, breast and other cancers ... measure and defend their own actions against their peers Dr Hayworth and other doctors could reassure themselves that some unanticipated and feared events were exceptions to the rule and thus not ... gender norms and roles, and unquestioned scientific authority, on the social side; and reflecting progress in prevention (SBE and mammography) and treatment (less radical surgery and chemotherapy...
Ngày tải lên: 06/03/2014, 00:22
Báo cáo khoa học: WFIKKN1 and WFIKKN2 bind growth factors TGFb1, BMP2 and BMP4 but do not inhibit their signalling activity docx
... and lM) with TGFb1; (D) WFIKKN2 (250 AND 500 nM, and 1, and lM) with TGFb1; (E) WFIKKN1 (400 and 750 nM, and lM) with BMP2; (F) WFIKKN2 (50, 100, 250 and 500 nM) with BMP2; (G) WFIKKN1 (500 and ... extracellular multidomain proteins that contain a WAP domain, a Follistatin ⁄ Kazal domain, an immunoglobulin domain, two Kunitz-type protease inhibitor domains and an NTR domain [11,12] The ... 750 nM, and 1.5 lM) with BMP3; (H) WFIKKN2 (100, 250 and 500 nM, and lM) with BMP3; (I) WFIKKN1 (250, 500 and 750 nM, 1, 1.25, 1.5 and lM) with BMP8b; (J) WFIKKN2 (250, 500 and 750 nM, and 1.5...
Ngày tải lên: 06/03/2014, 02:20
báo cáo hóa học:" Human immunodeficiency virus and human papilloma virus - why HPV-induced lesions do not spontaneously resolve and why therapeutic vaccination can be successful" pot
... HIV[41] and while HIVinduced immunosuppression can be held accountable for the increased incidence of precursor lesions it does not explain why these lesions not resolve when HAART is given and immunosuppression ... infections and the detection of T-cell responses against agents such as CMV [35], Candida, Mycobacterium and Streptococcus [36,37] This occurs a few months after therapy has commenced and is thought ... [46] The persistence of HPV and HPV-induced lesions indicate that HPV-infection was not counteracted in the first place and that the virus was allowed to establish LSIL and/ or HSIL lesions before...
Ngày tải lên: 18/06/2014, 15:20
d. Hadn''''t it been b 41. The talks in the classroom, in the corridor and in the schoolyard do not pdf
... yesterday ……… you ……… them? a bought / Do / like b buys / Do / like c bought / Did / like d bought / Don’t / like >a 26 The order to abandon the ship was given and hundreds of people into the icy ... happened to notice the old lady to get out of bed a has tried b to try c trying d tried c 13 Recently, there have been several outbreaks of disease like legionnaire’s syndrome, and doctors don’t ... c III Grammar and Vocabulary: 11 Oh, dear, I see we’ve ……… coffee Do you mind drinking tea? a done without b gone off c run out of d turned out > c 12 I wish that the weather not so cold a...
Ngày tải lên: 18/06/2014, 17:20
Báo cáo hóa học: " Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infection" potx
... and μl of QuantumRNA™ 18S internal standard (Ambion, Austin, TX) at a primer:competimer ratio of 4:6 for CYP 3A2 and 2C11 and 3:7 for PXR and RXR reactions Gene-specific reaction conditions and ... study They were reduced by 42%, 40% and 41% after 24 hours, 4, and 14 days (Figure 3B, C, and 3D, p ≤ 0.01) Contrary to these findings, the UV inactivated virus did not alter CYP3A2 mRNA Twenty-four ... animals given AdlacZ, PEGAd, and HDAd (27, 27, and 39%, of control respectively, Figure 3D, p ≤ 0.01) Effect of a single dose of virus on hepatic CYP2C11 expression and function CYP2C11 protein...
Ngày tải lên: 20/06/2014, 01:20
báo cáo khoa học:" Predictors of health status do not change over three-year periods and exacerbation makes difference in Chronic Obstructive Pulmonary Disease" ppsx
... stages I and II, and also for patients in stage III than for patients in stage I and for patients in stage II than patients in stage I We did not identify differences between stages II and III and ... stages II and III and stages III and IV after three years In the BODE classification, we found that HS change between the classes and 2, classes and and classes and after three years 10 Seventy-two ... (Figure 4) and on activity domain [OR 1.67 (95% IC 1.04-2.03); p=0.031] Predictor variables of clinically significant stability/improvement or worsening on SGRQ symptom and impact domains were not identified...
Ngày tải lên: 11/08/2014, 23:22
Báo cáo khoa học: "Recently published papers: What not to do and how not to do it" ppsx
... treatment arm and 1.0 in the placebo arm The authors’ well argued discussion and the accompanying editorial [16] both conclude that a larger randomized trial of this intervention is warranted Of note, ... study establishing a link between hypoproteinaemia and poor outcome in ALI [14] They then went on to conduct a randomized controlled trial of albumin and furosemide versus placebo in a small group ... patients randomly allocated to have a pulmonary artery catheter or not The majority of patients allocated to the control arm had access to alternative methods of cardiac output monitoring and no...
Ngày tải lên: 12/08/2014, 22:22
Báo cáo khoa học: " Do-not-resuscitate orders, unintended consequences, and the ripple effect" docx
... non-neurocritical care is not known As we increase our emphasis in critical care on end-of-life issues and compassionate palliative care, it is essential not to Page of (page number not for citation purposes) ... Rosenthal GE: Increased risk of death in patients with do- not- resuscitate orders Med Care 1999, 37:727-737 Beach MC, Morrison RS: The effect of do- not- resuscitate orders on physician decision-making ... DNR orders themselves So what are we to do? Just instituting a policy prohibiting DNR orders within 24 hours of hospital admission is not the answer It is not the DNR orders themselves, but it...
Ngày tải lên: 13/08/2014, 03:20
Báo cáo y học: "Neck pain and anxiety do not always go together" doc
... 4.46 (with minimum and maximum values ranging between and 10) and the mean number of pain days in the preceding 12 months was 156 (with minimum and maximum values ranging between and 365 days) A ... descriptive analysis of mean, minimum and maximum values and standard deviation (SD) For comparisons a combination of non-parametric (Mann Whitney-U test) and parametric (Independent samples T-test) ... our study and remaining respectful of Occam’s razor, we offer three perspectives: Firstly, our observations may indicate that chronic and/ or intense non-specific neck pain simply does not trigger...
Ngày tải lên: 13/08/2014, 14:20
Families who do not send their children to state- run schools should not be reqiured to pau educationa tã
... perceived costs and benefits of each option Only the total separation of state and school can re-institute parental responsibility, protect parents' rights, and allow students, schools, and teachers ... educationally By and large, education is an economic commodity to be purchased in the marketplace according to the preferences and valuations of education consumers In a free education market parents and ... their individual children and should be permitted to select the appropriate education for each of them It is critical that parents purchase education directly, when, and only for as long as, they...
Ngày tải lên: 16/09/2013, 23:10
Why medicine and why not
... lawbreaking Habits start young, and patients have a right to expect high standards of doctors and doctors in training, higher standards than society may demand of others Those not prepared for such personal ... a unique passport to the minds and bodies of all Why medicine and why not? kinds and conditions of men, women, and children In return the doctor has the ethical and practical duty to work uncompromisingly ... might not as well, or better Confidence based on competence and the ability to understand and cope is quite another matter; it is appreciated by patients and colleagues alike Respect for others and...
Ngày tải lên: 01/11/2013, 09:20
Tài liệu Báo cáo khoa học: "On Learning Subtypes of the Part-Whole Relation: Do Not Mix your Seeds" pdf
... generic placeholders PART and WHOLE Below, we show two dependency paths (1-b) and (2-b), respectively derived from English and Dutch Wikipedia sentences (1-a) and (2-a), and denoting the relations ... Guarino, C Masolo, A Oltramari, and L Schneider 2002 Sweetening ontologies with DOLCE Knowledge Engineering and Knowledge Management: Ontologies and the Semantic Web, Lecture Notes in Computer Science, ... the seed-sets We parsed the English and Dutch corpora respectively with the Stanford3 (Klein and Manning, 2003) and the Alpino4 (van Noord, 2006) parsers, and formalized the relations between...
Ngày tải lên: 20/02/2014, 04:20
Tài liệu Kích hoạt tính năng Do not Track trong Firefox potx
... bạn cách cho phép Do not Track Firefox Bước 1: Click nút Firefox góc trái trình duyệt Web bạn chọn Options Bước 2: Click tab Privacy Bước 3: Đánh dấu lựa chọn “Tell website I not want to be tracked”, ... tuyến ngày quan tâm, hoạt động bạn giới mạng bị theo dõi để lấy thông tin, để quảng cáo ….Vậy Do not Track cố gắng để bảo vệ bạn khỏi việc theo dõi tùy chọn làm để giúp bạn ngăn chặn việc Theo...
Ngày tải lên: 27/02/2014, 00:20
look at the important information in this header.1look at the important information in this header.We encourage you to keep this file on your own disk, keeping an electronic path open for the next readers. Do not remove this. **Welcome To The World o doc
... will show me the door, and fancy that I am not speaking the truth I am in love with you ." She did not laugh at him, though, and she did not show him the door Things did not drag on long, ... any happier with another man Indiana does not find fault with Colonel Delmare for being the husband that he is, but simply for being the husband! "She did not love her husband, for the mere reason, ... Romanticism had demanded the freedom of the individual, and the writers at the head of this movement were Chateaubriand, Victor Hugo and Dumas They claimed this freedom for Rene, for Hermann and for Antony,...
Ngày tải lên: 06/03/2014, 23:21
Government Bonds and Their Investors: What Are the Facts and Do They Matter? ppt
... regulation for banks, and US$425 billion owing to Dodd-Frank and FASB reforms for pension and insurance funds This total corresponds to percent of outstanding treasury bonds and 0.8 percent of the ... investor base and yields In Japan, a large domestic investor base has been associated with the low and stable yields despite very high debt (Tukuoka, 2010; Fidora et al., 2006) This large domestic ... directly and are therefore often omitted from the analysis The domestic financial sector is broken down into banks (excluding the central bank where possible), insurance and pension funds, and other...
Ngày tải lên: 15/03/2014, 07:20
.Get More and Do More at Dummies.com ®Start with FREE Cheat SheetsCheat Sheets include • Checklists • Charts • Common Instructions • And Other Good Stuff!To access the Cheat Sheet created specifically for this book, go towww.dummies.com/cheatsheet/e pptx
... variety of print and electronic formats and by print-on-demand Some material included with standard print versions of this book may not be included in e-books or in print-on-demand If this book ... For Dummies and Index Investing For Dummies No stranger to the mass media, Wild has shared his wit and wisdom on such shows as Oprah, The View, CBS Morning News, and Good Day New York, and in hundreds ... intelligent I don’t try to convince you that ETFs are your best investment choice, and I certainly don’t tell you that ETFs will make you rich Instead, I lay out facts and figures and summarize...
Ngày tải lên: 16/03/2014, 21:20