what hormone is responsible for raising calcium blood levels
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... carnitine: 1 mm (for standard comparison with other published data), and a concentration equal to the K m for carnitine of each enzyme (for comparison between mutants). In this article, we show ... sequence as being responsible for the pecu- liar kinetic characteristics of this enzyme, acting as a negative determinant for malonyl-CoA sensitivity. Asp17 may account, at least in part, for the high degree ... nat- urally occurring variation, Glu17, is responsible for both the low malonyl- CoA sensitivity and high carnitine affinity characteristics of the pig enzyme. This is the first demonstration that a single...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc
... active conformation, Val371 forms contacts with neighboring residues that are important for stabi- lizing the active state (e.g. Asp189, which is part of the S1 pocket responsible for the binding ... sequence identity of 30–45%), this position is occupied solely by a valine. This conserved amino acid is replaced by isoleucine in the Val371Ile FXI mutant. Interestingly, an isoleucine residue natu- rally ... the substrate) [26]. Consequently, substitution of Val371 to isoleucine might prevent the full development of the active conformation. This hypothesis is further con- firmed by the results of FIX proteolytic...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx
... factor that favors lysogeny and is responsible for primary control of the lambda develop- mental decision for lysis or lysogeny [4,7–9]. In the absence of CIII, CII is rapidly degraded by the ATP- dependent ... However, this proteolysis is much slower in vitro, because of a lack of chaperone machin- ery. The in vitro proteolysis requires ATP [14]. We examined the proteolysis of purified r 32 -C-his (1.2 ... CIII- mediated inhibition of proteolysis of r 32 by HflB is unknown. We tried to address this issue by studying the effects of CIII and CIIIC on the proteolysis of Keywords antiproteolytic activity;...
Ngày tải lên: 23/03/2014, 10:20
Báo cáo khoa học: PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast pdf
Ngày tải lên: 29/03/2014, 22:21
Báo cáo khoa học: " Biological impact of geometric uncertainties: what margin is needed for intra-hepatic tumors" ppsx
Ngày tải lên: 09/08/2014, 09:20
Báo cáo y học: " JNK activation is responsible for mucus overproduction in smoke inhalation injury" potx
Ngày tải lên: 12/08/2014, 13:22
Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
... prior to hydrolysis. The low-affinity state was observed to be retained immediately post-hydrolysis. Therefore, the dissoci- ation of phosphate and ⁄ or ADP is likely to be responsible for resetting of ... that ABCG2 R482G remains in a conformation that contains a low-affinity binding site for [ 3 H]daunomycin imme- diately post-nucleotide hydrolysis. Discussion A precise molecular mechanism for substrate translo- cation ... obtained from the hydrolysis process is used to reset the transporter. That ATP binding is responsible for the shift in binding affinity from high to low has now been demonstrated for all three eukaryotic multidrug...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... hydrolysis), corresponding to that expected for the F variant. This result is the first evidence for the heterozy- gous status (M/F) of the individual goat milk analysed. In addition to this, t ... subsequently distin- guished after a second amplification which allows discrim- ination between the alleles on the basis of the f ragment sizes (Fig. 8 , Step IIA). In the first step, a 266-bp (265 bp for ... the origin of the a s1 -CasM allele. This is, to our knowledge, t he first hypothesis o f a genomic recombination event to account for genetic polymorphism at a locus encoding a milk protein. MATERIALS...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... emission at 340 nm when Fura-2 is bound to calcium; B, excitation and emis- sion at 380 nm when Fura-2 is free). Intracellular calcium levels can then be calculated from Eqn (1) where K d is ... clinical model that is giving novel molecular mechanistic insight is adenocarcinoma of the oesopha- gus [2]. This cancer is one of the fastest rising cancers in the west, is taking the place ... Moravian Biotechnologies. Calcium determinations The fluorescent indicator Fura-2 (Molecular Probes) was used to measure cytosolic-free calcium levels in cells. When Fura-2 is bound to calcium it is excited...
Ngày tải lên: 23/03/2014, 10:21
Báo cáo hóa học: "TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status" pot
Ngày tải lên: 18/06/2014, 16:20
Báo cáo y học: " Recently published papers: Delivery, volume and outcome – what is best for our patient" pps
Ngày tải lên: 13/08/2014, 08:20
Tài liệu What it is and How to Prepare pdf
... healthy adults may be at increased risk for problems. What Is Avian Flu? Avian flu, also called bird flu, is a disease found in wild and farm birds. There is a concern that the bird flu will ... 3. Listen for Information Stay calm and get as many facts as you can. • Listen for reports on the television, radio or Internet. • Go to www.pandemicflu.gov or www.ohiopandemicflu.gov for ... prepare: 1. Make a plan for you and your family at home. Plan for how a pandemic might affect your work. 2. Prepare an emergency kit of supplies. 3. Listen for information about what to do and where...
Ngày tải lên: 20/12/2013, 23:15
Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt
... (<34 ng/POCIS) NC (<14 ng/POCIS) 37 ng/POCIS 40 ng/POCIS 20 ng/POCIS Ethopabate NC (<20 ng/POCIS) NC (<20 ng/POCIS) NC (<20 ng/POCIS) NC (<20 ng/POCIS) NC (<20 ng/POCIS) NC (<20 ... ng/POCIS) Endosulfan II NC (<10 ng/POCIS) NC (<10 ng/POCIS) NC (<10 ng/POCIS) NC (<10 ng/POCIS) NC (<10 ng/POCIS) NC (<10 ng/POCIS) NC (<10 ng/POCIS) NC (<10 ng/POCIS) cis-Permethrin NC ... (<4 ng/POCIS) NC (<4 ng/POCIS) NC (<4 ng/POCIS) NC (<4 ng/POCIS) NC (<4 ng/POCIS) NC (<4 ng/POCIS) NC (<4 ng/POCIS) Cyromazine NC (<20 ng/POCIS) NC (<20 ng/POCIS) NC (<20...
Ngày tải lên: 14/02/2014, 08:20
Tài liệu Báo cáo khoa học: A DExD⁄ H box RNA helicase is important for K+ deprivation responses and tolerance in Arabidopsis thaliana docx
... re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Analysis ... knowledge, this is the first report of a plant DEVH box RNA helicase regulating K + deprivation tolerance. This study provides a valuable reference for future research in this area. Results AtHELPS is a ... worldwide distribution of K + is incon- sistent [2]. In the tropics and subtropics, one-quarter of the soil has been threatened because of a lack of K + [3]. K + is essential for plants, and is required...
Ngày tải lên: 14/02/2014, 18:20