what hormone is responsible for increasing blood calcium levels
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... carnitine: 1 mm (for standard comparison with other published data), and a concentration equal to the K m for carnitine of each enzyme (for comparison between mutants). In this article, we show ... sequence as being responsible for the pecu- liar kinetic characteristics of this enzyme, acting as a negative determinant for malonyl-CoA sensitivity. Asp17 may account, at least in part, for the high degree ... nat- urally occurring variation, Glu17, is responsible for both the low malonyl- CoA sensitivity and high carnitine affinity characteristics of the pig enzyme. This is the first demonstration that a single...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc
... active conformation, Val371 forms contacts with neighboring residues that are important for stabi- lizing the active state (e.g. Asp189, which is part of the S1 pocket responsible for the binding ... sequence identity of 30–45%), this position is occupied solely by a valine. This conserved amino acid is replaced by isoleucine in the Val371Ile FXI mutant. Interestingly, an isoleucine residue natu- rally ... the substrate) [26]. Consequently, substitution of Val371 to isoleucine might prevent the full development of the active conformation. This hypothesis is further con- firmed by the results of FIX proteolytic...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx
... factor that favors lysogeny and is responsible for primary control of the lambda develop- mental decision for lysis or lysogeny [4,7–9]. In the absence of CIII, CII is rapidly degraded by the ATP- dependent ... However, this proteolysis is much slower in vitro, because of a lack of chaperone machin- ery. The in vitro proteolysis requires ATP [14]. We examined the proteolysis of purified r 32 -C-his (1.2 ... CIII- mediated inhibition of proteolysis of r 32 by HflB is unknown. We tried to address this issue by studying the effects of CIII and CIIIC on the proteolysis of Keywords antiproteolytic activity;...
Ngày tải lên: 23/03/2014, 10:20
Báo cáo khoa học: PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast pdf
... synthesis, it might be involved in the stearic acid incorporation after the de novo synthesis of this lipid (i.e. the second hypothesis). According to this hypothesis, previously raised for mammals ... from the European S. cerevisiae Archive for Functional Analysis (EUROSCARF) library. BY4742 (MATa; his3D1; leu2D0; lys2D0; ura3D0) is a wild-type strain and psi1D (MATa; his3D1; leu2D0; lys2D0; ... strongly that PI is remodeled in microsomal membranes before being transferred to mitochondria or, in other words, that Psi1p is located in the micro- somal membranes. This finding is in agreement...
Ngày tải lên: 29/03/2014, 22:21
Báo cáo khoa học: " Biological impact of geometric uncertainties: what margin is needed for intra-hepatic tumors" ppsx
Ngày tải lên: 09/08/2014, 09:20
Báo cáo y học: " JNK activation is responsible for mucus overproduction in smoke inhalation injury" potx
Ngày tải lên: 12/08/2014, 13:22
Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
... prior to hydrolysis. The low-affinity state was observed to be retained immediately post-hydrolysis. Therefore, the dissoci- ation of phosphate and ⁄ or ADP is likely to be responsible for resetting of ... of ATP per se is the ‘power stroke’ for drug translocation, and that energy obtained from the hydrolysis process is used to reset the transporter. That ATP binding is responsible for the shift ... that ABCG2 R482G remains in a conformation that contains a low-affinity binding site for [ 3 H]daunomycin imme- diately post-nucleotide hydrolysis. Discussion A precise molecular mechanism for substrate translo- cation...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... hydrolysis), corresponding to that expected for the F variant. This result is the first evidence for the heterozy- gous status (M/F) of the individual goat milk analysed. In addition to this, t ... subsequently distin- guished after a second amplification which allows discrim- ination between the alleles on the basis of the f ragment sizes (Fig. 8 , Step IIA). In the first step, a 266-bp (265 bp for ... the origin of the a s1 -CasM allele. This is, to our knowledge, t he first hypothesis o f a genomic recombination event to account for genetic polymorphism at a locus encoding a milk protein. MATERIALS...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... emission at 340 nm when Fura-2 is bound to calcium; B, excitation and emis- sion at 380 nm when Fura-2 is free). Intracellular calcium levels can then be calculated from Eqn (1) where K d is ... clinical model that is giving novel molecular mechanistic insight is adenocarcinoma of the oesopha- gus [2]. This cancer is one of the fastest rising cancers in the west, is taking the place ... Moravian Biotechnologies. Calcium determinations The fluorescent indicator Fura-2 (Molecular Probes) was used to measure cytosolic-free calcium levels in cells. When Fura-2 is bound to calcium it is excited...
Ngày tải lên: 23/03/2014, 10:21
Báo cáo hóa học: "TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status" pot
Ngày tải lên: 18/06/2014, 16:20
Báo cáo y học: " Recently published papers: Delivery, volume and outcome – what is best for our patient" pps
Ngày tải lên: 13/08/2014, 08:20
the virtual jirga the 2009 education policy and the medium of instruction debate in pakistan who is participating and what are the implications for balochistan
Ngày tải lên: 22/12/2014, 16:41
Flavor enhancement as a tool for increasing pleasantness and intakeof a snack product among the elderly
... receiving no additional information, except for the list of ingredients. The written information was provided on the front page of the home-use booklet. Preliminary data analysis revealed no significant ... presence of health-related information. Since the effects of information were negligible, and not relevant enough for this study, the data were pooled together over the information conditions. Olfactory ... especially the managing director Merja Scharlin, is thanked for providing samples and for co-operation. This study was financially supported by the European Commis- sion’s Quality of Life Fifth Framework...
Ngày tải lên: 03/04/2013, 21:06
Tài liệu What it is and How to Prepare pdf
... healthy adults may be at increased risk for problems. What Is Avian Flu? Avian flu, also called bird flu, is a disease found in wild and farm birds. There is a concern that the bird flu will ... 3. Listen for Information Stay calm and get as many facts as you can. ã Listen for reports on the television, radio or Internet. ã Go to www.pandemicflu.gov or www.ohiopandemicflu.gov for ... prepare: 1. Make a plan for you and your family at home. Plan for how a pandemic might affect your work. 2. Prepare an emergency kit of supplies. 3. Listen for information about what to do and where...
Ngày tải lên: 20/12/2013, 23:15