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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

... by growth in iron-rich media. We have also shown that the increase in the prooxidant state caused by iron loading has an impact in protein integrity, as indicated by an increase in protein-bound ... localizes in the cytoplasm of human epithelial cells of the gastrointestinal tract and liver, two central organs in the regulation of iron metabolism [20,21]. After their synthesis in the endo- plasmic ... background staining (thin lines). Cells were then acquired in a FACScali- bur and analyzed using CELLQUEST. (A) Histograms show the expression of the molecules studied in HepG2 cells cultured in the absence (–...

Ngày tải lên: 19/02/2014, 16:20

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THE FIRST BANK OF THE UNITED STATES - A CHAPTER IN THE HISTORY OF CENTRAL BANKING pdf

THE FIRST BANK OF THE UNITED STATES - A CHAPTER IN THE HISTORY OF CENTRAL BANKING pdf

... Clearly, the new nation’s leaders had their work cut out for them: re-establishing commerce and industry, repaying war debt, restoring the value of the currency, and lowering in ation. Proposing ... and in 1811, during his administration, the bank’s charter expired. However, aer the War of 1812, the government once again found itself with mounting debt and the country in increasing economic ... Without the restraining hand of the Bank of the United States, state banks became less cautious in their lending habits and credit expanded rapidly. In eect, the country found itself in circumstances...

Ngày tải lên: 22/03/2014, 21:20

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Walking in the sun potx

Walking in the sun potx

Ngày tải lên: 23/06/2014, 01:20

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Tài liệu Central bank rates, market rates and retail bank rates in the euro area in the context of the recent crisis docx

Tài liệu Central bank rates, market rates and retail bank rates in the euro area in the context of the recent crisis docx

... Conversely, in the case of the model estimated using the OIS, both the increase and decrease in the retail interest rate are principally due to the shock to the retail rate, which indicates ... is insuf- ficient for explaining the events during the crisis. The savings deposit interest rate is particularly important in Belgium, because it includes the interest rate applied to savings ... overnight interbank lending in the euro area. Under normal circumstances, this is the rate that the ECB seeks to in uence. In the years preceding the crisis, the market interest rates likely to be the...

Ngày tải lên: 15/02/2014, 05:20

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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... appears stronger in G 2 ⁄ M than in G 1 [44]. This contradicts repression through a complex in G 1 and in vivo foot- printing results in the original definition of the sites [10]. Taken together, the sites in ... specifying partic- ular binding sites [20,22,61,90,92–96]. Very recently, it has been shown that Lin-54 can bind to two sites in the Cdc2 promoter in vitro. Lin-54 binds in EMSAs to a region in the ... in a recent report, that in the presence of p53 the DREAM com- plex switches from containing activating B-Myb to repressing E2F4 ⁄ p130. Although the report does not specify binding sites, other...

Ngày tải lên: 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers ppt

Tài liệu Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers ppt

... quantify the amount of recovered protein owing to the presence of a high molar excess of BSA remaining in the buffer. Therefore, a fixed aliquot of the protein was incubated with the indicated ... sequence, increasing the number of basic residues of lysine, arginine and histidine, could occur. However it seemed probable that the eEF1A isoforms could act as a controlling event in maintaining the viability ... cells. One hypothesis may be that these oligomers exert their action by blocking the binding of eEF1A to its ligand in cancer cells, perhaps to zinc finger proteins involved in the modulation of...

Ngày tải lên: 21/02/2014, 00:20

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Báo cáo " Community based coastal resources management behind changes in surface water environment and land policy: A case study in the Tam Giang Lagoon, Central Vietnam " ppt

Báo cáo " Community based coastal resources management behind changes in surface water environment and land policy: A case study in the Tam Giang Lagoon, Central Vietnam " ppt

... these regulations, the resource users, instead of independent unit in using the lagoon’s resources as before, have to join in the FA. When they become the FA’s member, they will have legal ... other in exploiting and aquaculture within its team”. There are 75 households who participated in these teams. Some of these members are also the households that have been mentioned in the ... them are not being able to invest additional money to continue shrimp aquaculture. The decrease in their revenues due to serious disease during these periods made them unable to cover the...

Ngày tải lên: 14/03/2014, 15:20

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Poisoning the Well: How the EPA is Ignoring Atrazine Contamination in Surface and Drinking Water in the Central United States pot

Poisoning the Well: How the EPA is Ignoring Atrazine Contamination in Surface and Drinking Water in the Central United States pot

... levels. Therefore, the endocrine-disrupting effects of atrazine on animals were not incorporated into the determination of the level of concern associated with the contamination in the watershed. ... recommends phasing out the use of atrazine, more effective atrazine monitoring, the adoption of farming techniques that can help minimize the use of atrazine and prevent it from running into waterways, ... of atrazine as well as the presence of atrazine in drinking water. Under the Safe Drinking Water Act (SDWA), the EPA has determined that no more than 3 parts per billion (ppb) of atrazine (as...

Ngày tải lên: 15/03/2014, 10:20

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Preferences of the Central Reserve Bank of Peru and optimal monetary policy rules in the inflation targeting regime ppt

Preferences of the Central Reserve Bank of Peru and optimal monetary policy rules in the inflation targeting regime ppt

... the tolerance interval set by the CRBP in the inflation targeting regime. The present sampling period ends in 2008:02, 19 as the macroeconomic variables were influenced by the effects of the ... to prices in the long run. 24 points, revealing a procyclical behavior towards the output gap. However, an increase of one percentage point in the inflation rate pushes the interest ... approximated by the interbank rate. 32 Note that the optimal interest rate captures the main movements of the observed interest rate. However, there are some inconsistencies, especially in the first...

Ngày tải lên: 15/03/2014, 14:20

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Report of the Sub-Committee of the Central Board of Directors of Reserve Bank of India to Study Issues and Concerns in the MFI Sector doc

Report of the Sub-Committee of the Central Board of Directors of Reserve Bank of India to Study Issues and Concerns in the MFI Sector doc

... entities in the financial system. Incidentally even the Act does not make any mention of interest rates except that the total interest cannot exceed the principal amount of the loan. On the other ... either an increase in the size of the average individual loan given to the borrower or is an indication of multiple lending/over borrowing resulting from more than one loan being given to the same ... repayable within 12 months irrespective of the amount of the loan. However, the larger the loan, the larger the amount of the repayment installment, and a large installment may strain the repayment...

Ngày tải lên: 15/03/2014, 14:20

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Báo cáo khóa học: Endoplasmic reticulum-associated degradation of glycoproteins bearing Man5GlcNAc2 and Man9GlcNAc2 species in the MI8-5 CHO cell line docx

Báo cáo khóa học: Endoplasmic reticulum-associated degradation of glycoproteins bearing Man5GlcNAc2 and Man9GlcNAc2 species in the MI8-5 CHO cell line docx

... respectively, when the incubation was performed in the presence of 20 l M kifunensine after a 20 min preincuba- tion. G1M9 indicates oligomannosides con- taining one Glc, nine Man, and two GlcNAc residues. ... Zonneveld, D., Cacan, R., Buttin, G. & Braakman, I. (2000) Truncated N-glycans affect protein folding in the ER of CHO-derived mutant cell lines without preventing calnexin binding. Glycobiology 10, ... with [2- 3 H]Manfor1hafter20minpreincubationin0.175m M Glc and chased for 1 h in culture medium containing 5 m M Glc and 5 m M Man in the presence (C) or absence (A, B) of 1 m M DIM. Cells were then submitted to the...

Ngày tải lên: 16/03/2014, 16:20

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Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx

Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx

... within 1 min of TCDD treatment in L-MAT cells (with the peak being reached at 20 min and the level sustained until 120 min, after which it decreased). However, there was no significant change in the ... clarify the involvement of PKC in the signal transduction mechanism participa- ting in TCDD-induced cellular responses [14]. We also looked for evidence of the involvement of PKC in the signal ... TCDD-induced apoptosis in the human T-cell line, L-MAT, because AhR does not exist in L-MAT [7,8]. In view of our previous findings and the very high susceptibility to TCDD among T-cell lines (A....

Ngày tải lên: 23/03/2014, 13:20

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Báo cáo khoa học: Calpain 1–titin interactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myofibril doc

Báo cáo khoa học: Calpain 1–titin interactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myofibril doc

... N2 -line level, whereas two less-intense precipitate lines are pre- sent in the vicinity of the Z -line (Fig. 5C). In stored muscle, the transversal fracture line is obviously adja- cent to the ... Z -line to the M-band of the sarcomeres [23–25]. Two calpain 3-binding sites, located at the C-terminal end of titin (M -line region) and at the N2 -line region (a transverse dense structure at the ... to peroxidase labelling, density increasing of the Z -line, in particular at the edges of the structure, confirms the immunofluorescent staining. On the other hand, labelling of the Z-band region...

Ngày tải lên: 23/03/2014, 13:20

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Báo cáo khoa học: Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703 pdf

Báo cáo khoa học: Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703 pdf

... less effective than the expected effects based on tests of the compounds individually. Simply put, the point representing the dose combination lying on, below, or above the straight line represents ... TRAIL on the liver carcinoma cells QGY-7703 To investigate the apoptotic function of TRAIL containing the extracellular domain (amino acids 114–281) of the human liver cancer cell line, QGY-7703 ... CA, USA). The cells were maintained in RPMI-1640 containing 10% heat-inactivated bovine serum, 1 m ML -glutamine, 100 Uặml )1 penicillin and 100 lgặml )1 streptomycin (Life Technologies, Inc. Grand Island,...

Ngày tải lên: 23/03/2014, 17:22

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